IGSF9 and TMEM65

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		IGSF9	TMEM65
Description		immunoglobulin superfamily member 9	transmembrane protein 65
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Axon Dendrite Synapse Inhibitory Synapse Postsynaptic Density Membrane Glutamatergic Synapse	Nucleolus Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Intercalated Disc Membrane
	Molecular Function	Protein Binding Cell-cell Adhesion Mediator Activity	Protein Binding
	Biological Process	Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Nervous System Development Axon Guidance Dendrite Development Cell Differentiation Regulation Of Synapse Organization Dendrite Self-avoidance Regulation Of Synapse Maturation	Cardiac Ventricle Development Cardiac Conduction Regulation Of Cardiac Conduction
Pathways
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545)	Fear of minor pain ( 28701861)
Interacting Genes		5 interacting genes: ASCC2 CYB5B PAQR5 SHANK3 TMEM65	33 interacting genes: ABHD16A AQP6 ARL13B CYB561 CYBRD1 EBP ERGIC3 FAM174A FAM209A GJA8 GPR42 HSD17B11 IGSF9 IL3RA JAGN1 JPH1 LMNA MSMO1 PDZK1IP1 PTGES PVR REEP4 RETREG3 SCN3B SLC10A6 SLC18A1 SLC35H1 SLC7A8 TIMMDC1 TMEM101 TMEM80 TMX2 ZFYVE27
Entrez ID		57549	157378
HPRD ID		10001	14102
Ensembl ID		ENSG00000085552	ENSG00000164983
Uniprot IDs		Q9P2J2	Q6PI78
PDB IDs		1V5J
Enriched GO Terms of Interacting Partners?		Nitric-oxide Synthase Complex Nitrite Reductase (NO-forming) Activity Ribosome-associated Ubiquitin-dependent Protein Catabolic Process RQC-trigger Complex Guanylate Kinase-associated Protein Clustering Vocal Learning Negative Regulation Of Cell Volume Neuron Spine Postsynaptic Density Assembly Positive Regulation Of Long-term Neuronal Synaptic Plasticity AMPA Glutamate Receptor Clustering Synaptic Receptor Adaptor Activity Regulation Of Synapse Structural Plasticity Positive Regulation Of Synapse Structural Plasticity NMDA Glutamate Receptor Clustering Observational Learning Striatal Medium Spiny Neuron Differentiation Cardiac Ventricle Development DNA Alkylation Repair Positive Regulation Of Glutamate Receptor Signaling Pathway Postsynaptic Specialization Assembly GABAergic Neuron Differentiation Regulation Of Glutamate Receptor Signaling Pathway Neurotransmitter-gated Ion Channel Clustering DNA Repair Complex Auditory Behavior Regulation Of Long-term Synaptic Depression Mechanosensory Behavior Dendritic Spine Morphogenesis Postsynaptic Density Organization Nitric Oxide Biosynthetic Process Brain Morphogenesis Vocalization Behavior Positive Regulation Of Long-term Synaptic Potentiation K63-linked Polyubiquitin Modification-dependent Protein Binding Postsynaptic Specialization Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Cardiac Conduction	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Ascorbate Homeostasis Transmembrane Monodehydroascorbate Reductase Activity Endoplasmic Reticulum Transmembrane Transport Protein Binding
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