KIAA1328 and EEF2KMT

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		KIAA1328	EEF2KMT
Description		KIAA1328	eukaryotic elongation factor 2 lysine methyltransferase
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Protein-containing Complex
	Molecular Function	Protein Binding	Protein Binding Methyltransferase Activity Protein-lysine N-methyltransferase Activity Transferase Activity
	Biological Process		Peptidyl-lysine Trimethylation Methylation
Pathways			Protein methylation
Drugs
Diseases
GWAS		Body mass index ( 28552196) Ferritin levels ( 33491795) General risk tolerance (MTAG) ( 30643258) Metabolite levels ( 23823483) Periodontal disease-related phenotype (Socransky) ( 24347629) Reaction time ( 29844566) Simvastatin-induced myopathy ( 31220337) Weight ( 28552196)
Interacting Genes		29 interacting genes: AMOT ANKS1A ATG5 CARD9 CCDC13 CENPP CEP290 CFAP206 COPB1 DEF6 EAF1 EEF2KMT FAM161A FAM161B GOLGA1 LMO1 LNX1 MTMR9 NEK6 PICK1 PKN1 PRKAA2 SYCE1L TSG101 TSGA10 TTC23 TXLNA TXLNB ZGPAT	12 interacting genes: HPRT1 IFT88 KIAA1328 LNX1 NR0B1 PICK1 PRKAR1B PRTFDC1 TRIP13 ZNF213 ZNF35 ZNF620
Entrez ID		57536	196483
HPRD ID		17211	18018
Ensembl ID		ENSG00000150477	ENSG00000118894
Uniprot IDs		Q86T90	K7ES84 Q96G04
PDB IDs			8FZB
Enriched GO Terms of Interacting Partners?		Regulation Of Stress Granule Assembly Protein-containing Complex Negative Regulation Of Signaling Receptor Activity Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Negative Regulation Of Protein Tyrosine Kinase Activity Cytoskeleton	Guanine Salvage Hypoxanthine Phosphoribosyltransferase Activity GMP Catabolic Process Guanine Metabolic Process Purine Ribonucleoside Salvage Purine Nucleobase Biosynthetic Process Nucleoside Salvage Purine Nucleoside Monophosphate Catabolic Process Purine Nucleobase Metabolic Process Purine Nucleoside Metabolic Process GMP Metabolic Process Purine-containing Compound Salvage Nucleoside Metabolic Process Hippocampal Mossy Fiber To CA3 Synapse Ciliary Base DNA Hairpin Binding Guanine Phosphoribosyltransferase Activity Nucleoside Monophosphate Metabolic Process Purine Ribonucleotide Catabolic Process Hypoxanthine Salvage Purine Nucleotide Catabolic Process Adenine Metabolic Process Hypoxanthine Biosynthetic Process Meiotic Recombination Checkpoint Signaling Nucleotide Catabolic Process AF-2 Domain Binding Hypoxanthine Metabolic Process Response To Silicon Dioxide Membrane Curvature Sensor Activity GMP Salvage Nucleoside Phosphate Catabolic Process IMP Salvage Centriolar Satellite Male Gamete Generation Spermatogenesis Positive Regulation Of Dopamine Metabolic Process AMP Salvage Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation CAMP-dependent Protein Kinase Regulator Activity Female Meiosis I Gamete Generation Metal Ion Binding Positive Regulation Of Fear Response Meiotic Cell Cycle Checkpoint Signaling Negative Regulation Of Actin Nucleation
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