DANCR and ARF5

Number of citations of the paper that reports this interaction (PubMedID 31863900)
0

Data Source:
BioGRID (unspecified method)

		DANCR	ARF5
Description		differentiation antagonizing non-protein coding RNA	ARF GTPase 5
Image		No pdb structure
GO Annotations	Cellular Component		Cytoplasm Golgi Apparatus Plasma Membrane Membrane Perinuclear Region Of Cytoplasm Extracellular Exosome
	Molecular Function		Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process		Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Protein Transport Vesicle-mediated Transport
Pathways			COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS			Type 2 diabetes ( 23532257)
Interacting Genes		20 interacting genes: AP1G2 ARF5 CAV1 EZH2 FOXO1 G3BP2 GLRX3 HNRNPA1 KRT9 NCL NONO PKM PSPC1 RBM25 SERBP1 SRSF1 SYT1 TPM4 YBX1 YBX3	20 interacting genes: AASS ACY3 AP1B1 AP3B1 ARFIP1 ARFIP2 ASAP2 DANCR DENND1A DENND1B DTX3 ERBB2 GGA1 GORAB IKBKG MPHOSPH9 PALS2 PIP5K1A RAB11FIP3 SNCA
Entrez ID		57291	381
HPRD ID			00055
Ensembl ID		ENSG00000226950	ENSG00000004059
Uniprot IDs			A4D0Z3 P84085
PDB IDs			2B6H
Enriched GO Terms of Interacting Partners?		Nucleic Acid Binding RNA Binding Regulation Of MRNA Metabolic Process Positive Regulation Of Cytoplasmic Translation Post-transcriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome DNA Topoisomerase Binding Regulation Of Cytoplasmic Translation MRNA Binding Cellular Response To Hyperoxia Regulation Of RNA Metabolic Process Regulation Of MRNA Processing Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Transport Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Peptide Hormone Stimulus RNA Splicing Regulation Of RNA Splicing Paraspeckles Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MRNA Stability MRNA Stabilization Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of Metabolic Process Negative Regulation Of Biosynthetic Process Cellular Response To Increased Oxygen Levels Negative Regulation Of RNA Metabolic Process Nucleobase-containing Compound Transport Regulation Of Translation Negative Regulation Of MRNA Catabolic Process Regulation Of RNA Stability RNA Stabilization MRNA Processing Regulation Of Protein Metabolic Process Negative Regulation Of RNA Catabolic Process Response To Hyperoxia Negative Regulation Of Necroptotic Process Negative Regulation Of MRNA Metabolic Process Cellular Response To Chemical Stress Positive Regulation Of Protein Metabolic Process Negative Regulation Of Programmed Necrotic Cell Death Regulation Of Circadian Rhythm Response To Peptide Hormone Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of RNA Biosynthetic Process Regulation Of The Force Of Heart Contraction Negative Regulation Of DNA-templated Transcription MRNA 3'-UTR Binding MRNA Transport	Cellular Localization Establishment Of Localization In Cell Localization Within Membrane Trans-Golgi Network Membrane Intracellular Protein Localization Golgi Apparatus Clathrin-coated Vesicle Membrane Protein Transport Vesicle-mediated Transport To The Plasma Membrane Vesicle-mediated Transport Intracellular Transport Establishment Of Protein Localization Cytosol Clathrin Adaptor Complex Endocytic Recycling Protein Localization To Cell Periphery Protein Domain Specific Binding Melanosome Assembly Endosomal Transport Establishment Of Vesicle Localization GTP-dependent Protein Binding Small GTPase Binding Intracellular Protein Transport Platelet Dense Granule Organization Protein Localization To Membrane Vesicle Localization Phospholipid Binding Ruffle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Early Endosome Phosphatidylinositol Phosphate Binding Membrane Coat Phosphatidylinositol-4-phosphate Binding Protein Localization To Cell Surface Regulation Of Actin Nucleation Synaptic Vesicle Transport Golgi To Plasma Membrane Protein Transport Melanosome Organization Pigment Granule Organization Cytoplasmic Vesicle Membrane Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Saccharopine Dehydrogenase (NADP+, L-lysine-forming) Activity Saccharopine Dehydrogenase Activity Saccharopine Dehydrogenase (NAD+, L-lysine-forming) Activity Saccharopine Dehydrogenase (NAD+, L-glutamate-forming) Activity Negative Regulation Of Retrograde Transport, Endosome To Golgi
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