KIAA1191 and NOL12

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		KIAA1191	NOL12
Description		KIAA1191	nucleolar protein 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion	Nucleus Nucleolus Cytoplasm
	Molecular Function	Protein Binding Oxidoreductase Activity	Single-stranded DNA Binding RNA Binding Protein Binding RRNA Binding Identical Protein Binding
	Biological Process
Pathways			Major pathway of rRNA processing in the nucleolus and cytosol
Drugs
Diseases
GWAS			Basophil count ( 32888494) Brain morphology (MOSTest) ( 32665545) Pulse pressure ( 30224653)
Interacting Genes		9 interacting genes: APP CACNA1A GSK3B NOL12 NOTCH1 POT1 PRNP RHOU SNCA	19 interacting genes: APP BEND7 CDCA7L CDK4 CEP70 DVL2 DVL3 KIAA1191 KRTAP10-6 KRTAP10-7 MCC SAP18 SF3B3 SLC25A38 SOD2 SPANXN2 SSX2IP TERF1 TSPYL2
Entrez ID		57179	79159
HPRD ID		13839	17537
Ensembl ID		ENSG00000122203	ENSG00000273899
Uniprot IDs		A0A087WT18 Q96A73	Q9UGY1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Amyloid-beta Response To Amyloid-beta Cellular Response To Copper Ion Response To Copper Ion Neuron Projection Organization Regulation Of Long-term Synaptic Potentiation Modulation Of Chemical Synaptic Transmission Regulation Of Synaptic Plasticity Positive Regulation Of Apoptotic Process Postsynapse Positive Regulation Of Programmed Cell Death Positive Regulation Of Neuron Apoptotic Process Regulation Of Neuron Apoptotic Process Cuprous Ion Binding Positive Regulation Of Establishment Of Protein Localization Regulation Of Calcium-mediated Signaling Negative Regulation Of Cellular Component Organization Negative Regulation Of Long-term Synaptic Potentiation Neuron Projection Maintenance Regulation Of Dendritic Spine Maintenance Negative Regulation Of Calcineurin-NFAT Signaling Cascade Intracellular Copper Ion Homeostasis Regulation Of Cellular Component Organization Regulation Of Generation Of Precursor Metabolites And Energy Negative Regulation Of Canonical Wnt Signaling Pathway Copper Ion Homeostasis Inclusion Body Regulation Of Protein Localization Regulation Of Neurotransmitter Uptake Regulation Of Calcium Ion Transmembrane Transport Positive Regulation Of Protein Localization Negative Regulation Of Calcium-mediated Signaling Regulation Of Presynapse Organization Negative Regulation Of Wnt Signaling Pathway Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Presynapse Assembly Molecular Function Activator Activity Cellular Response To Metal Ion Negative Regulation Of Stem Cell Differentiation Regulation Of Establishment Of Protein Localization Amyloid Fibril Formation Regulation Of Neuron Differentiation Microglial Cell Activation Positive Regulation Of Cellular Component Organization Leukocyte Activation Involved In Inflammatory Response Regulation Of Calcineurin-NFAT Signaling Cascade Negative Regulation Of Exocytosis Regulation Of Calcineurin-mediated Signaling Regulation Of Calcium Ion Transport Import Into Cell	Frizzled Binding Positive Regulation Of Neuron Projection Arborization Response To Manganese Ion Regulation Of Neuron Projection Arborization Positive Regulation Of JNK Cascade Amyloid-beta Complex Growth Cone Lamellipodium Positive Regulation Of Nitric Oxide Biosynthetic Process Regulation Of JNK Cascade Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Nitric Oxide Metabolic Process Response To Xenobiotic Stimulus Wnt Signaling Pathway, Planar Cell Polarity Pathway Acetylcholine-mediated Vasodilation Involved In Regulation Of Systemic Arterial Blood Pressure Erythrophore Differentiation Negative Regulation Of DNA Replication Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly Glycine Import Into Mitochondrion
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