PSMD9 and AHCYL1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PSMD9	AHCYL1
Description		proteasome 26S subunit, non-ATPase 9	adenosylhomocysteinase like 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Proteasome Regulatory Particle Proteasome Regulatory Particle, Base Subcomplex	Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Apical Plasma Membrane Intracellular Membrane-bounded Organelle Mitochondria-associated Endoplasmic Reticulum Membrane Contact Site Extracellular Exosome
	Molecular Function	Transcription Coactivator Activity Protein Binding BHLH Transcription Factor Binding	RNA Binding Adenosylhomocysteinase Activity Protein Binding Enzyme Regulator Activity Identical Protein Binding
	Biological Process	Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Insulin Secretion Positive Regulation Of DNA-templated Transcription Negative Regulation Of Insulin Secretion Proteasome Regulatory Particle Assembly	Protein Export From Nucleus One-carbon Metabolic Process Apoptotic Process Positive Regulation Of Sodium Ion Transport Regulation Of MRNA 3'-end Processing Regulation Of Monoatomic Ion Transmembrane Transporter Activity S-adenosylmethionine Cycle Angiotensin-activated Signaling Pathway Epithelial Fluid Transport Regulation Of Monoatomic Anion Transport Response To Calcium Ion Mitochondrion-endoplasmic Reticulum Membrane Tethering
Pathways		Proteasome assembly	PLC beta mediated events DAG and IP3 signaling Role of phospholipids in phagocytosis FCERI mediated Ca+2 mobilization Regulation of insulin secretion VEGFR2 mediated cell proliferation Ion homeostasis Ion homeostasis CLEC7A (Dectin-1) induces NFAT activation FCGR3A-mediated IL10 synthesis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS		Mean corpuscular volume ( 32888494) Mean platelet volume ( 24026423) Red blood cell count ( 32888494) Serum metabolite levels ( 33031748) Urinary metabolites (H-NMR features) ( 24586186)	Height ( 31562340)
Interacting Genes		21 interacting genes: AHCYL1 BANP BRCA1 CCDC136 CEP85L CKS1B CSH1 ELSPBP1 GH1 HNRNPA1 MEOX2 NCKIPSD PSMC6 RIN3 SKP2 TCF3 TNIP2 TRAF2 TRIM39 TRIM42 YY1	25 interacting genes: BID BTG3 CDKN2C CFTR DACH1 GEM HBQ1 HGS HSPA6 ITPR1 LRRK2 MEOX2 MFHAS1 PLEKHG5 PPL PRDM6 PSMD9 RNF6 SLC23A1 SOX30 SRPK1 SRPK2 SUMO2 UACA ZNF165
Entrez ID		5715	10768
HPRD ID		04394	07613
Ensembl ID		ENSG00000110801	ENSG00000168710
Uniprot IDs		O00233	A0A024R0A8 O43865
PDB IDs			3MTG
Enriched GO Terms of Interacting Partners?		Growth Hormone Receptor Binding Immunoglobulin V(D)J Recombination CD40 Signaling Pathway Mitogen-activated Protein Kinase Kinase Kinase Binding V(D)J Recombination Positive Regulation Of DNA Metabolic Process Endosome Lumen Growth Hormone Receptor Signaling Pathway
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