PSMD4 and MYOD1

Number of citations of the paper that reports this interaction (PubMedID 9235903)
0

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		PSMD4	MYOD1
Description		proteasome 26S subunit ubiquitin receptor, non-ATPase 4	myogenic differentiation 1
Image			No pdb structure
GO Annotations	Cellular Component	Proteasome Complex Nucleus Nucleoplasm Cytosol Proteasome Regulatory Particle, Base Subcomplex Proteasome Accessory Complex	Chromatin Euchromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Myofibril
	Molecular Function	RNA Binding Protein Binding Polyubiquitin Modification-dependent Protein Binding Identical Protein Binding Molecular Adaptor Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Nuclear Receptor Binding Enzyme Binding Chromatin DNA Binding Ubiquitin Protein Ligase Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Sequence-specific DNA Binding Protein Dimerization Activity RNA Polymerase II-specific DNA-binding Transcription Factor Binding E-box Binding Sequence-specific Double-stranded DNA Binding Promoter-specific Chromatin Binding
	Biological Process	Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Protein Phosphorylation Muscle Organ Development Myoblast Fate Determination Skeletal Muscle Tissue Development Myoblast Fusion Cellular Response To Starvation Tissue Development Regulation Of Gene Expression Myotube Differentiation Myotube Cell Development Myotube Differentiation Involved In Skeletal Muscle Regeneration Cell Differentiation Skeletal Muscle Cell Differentiation Muscle Cell Differentiation Muscle Cell Fate Commitment Skeletal Muscle Tissue Regeneration Positive Regulation Of Skeletal Muscle Tissue Regeneration Regulation Of RNA Splicing Skeletal Muscle Fiber Adaptation Myoblast Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Animal Organ Development Skeletal Muscle Fiber Development Positive Regulation Of Skeletal Muscle Fiber Development Striated Muscle Cell Differentiation Positive Regulation Of Muscle Cell Differentiation Cellular Response To Tumor Necrosis Factor Cellular Response To Glucocorticoid Stimulus Cellular Response To Estradiol Stimulus Cellular Response To Oxygen Levels Positive Regulation Of Myoblast Fusion Positive Regulation Of SnRNA Transcription By RNA Polymerase II Negative Regulation Of Myoblast Proliferation
Pathways		Proteasome assembly Proteasome assembly	Myogenesis Myogenesis TGFBR3 expression
Drugs
Diseases
GWAS		Body mass index ( 26426971) Hip circumference adjusted for BMI ( 34021172)	Body mass index ( 26426971) Hodgkin's lymphoma ( 34216518) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917)
Interacting Genes		46 interacting genes: ADRM1 APP BTRC CCNA2 CFTR CUL1 EGFR FBXO25 FLOT1 GNB5 H2AC4 H2BC3 ID1 MAP3K1 MDM2 MYOD1 NEDD4 NEDD4L NEDD8 NUB1 OGT PRKN PTEN RAD23A RAD23B RASSF8 RBCK1 RBM11 SCHIP1 SIAH2 SMURF1 SREBF2 STUB1 TCF3 TCP11L1 TMEM129 TP53 TRIM63 UBB UBC UBD UBE2C UBQLN1 UBQLN2 WWP2 XPC	67 interacting genes: AKAP19 AP1M1 ASCL3 BHLHA15 BHLHE40 BHLHE41 CALM1 CALM2 CALM3 CARM1 CDC34 CDK2 CDK4 CDKN1C CIB2 CREBBP CSRP3 ELSPBP1 EP300 EXOC3L1 FBXO32 FIGLA HAND1 HDAC1 HEY1 HSP90AA1 ID1 ID2 ID3 ID4 IFRD1 IGFN1 JUN KAT2B KAT5 KPNA3 LMO4 MDFI MEF2A MEF2C MOS MYOCD NCOR1 NCOR2 NR2F2 PHB2 POLR2G PRKCA PRMT5 PSMD4 PSME2 RB1 RORA RUNX1 RXRA SETD3 SMAD3 SMAD4 SMAD7 SP1 SRF STAT3 SUV39H1 TCF21 TCF3 TCF4 TWIST1
Entrez ID		5710	4654
HPRD ID		03386	01166
Ensembl ID		ENSG00000159352	ENSG00000129152
Uniprot IDs		P55036 Q5VWC4	P15172
PDB IDs		1P9C 1P9D 1UEL 1YX4 1YX5 1YX6 2KDE 2KDF 5GJQ 5GJR 5L4K 5LN3 5M32 5T0C 5T0G 5T0H 5T0I 5T0J 5VFP 5VFQ 5VFR 5VFS 5VFT 5VFU 5VGZ 5VHF 5VHH 5VHI 5VHS 6MSB 6MSD 6MSE 6MSG 6MSH 6MSJ 6MSK 6MUN 6U19 6WJD 6WJN 7QXN 7QXP 7QXU 7QXW 7QXX 7QY7 7QYA 7QYB 7W37 7W38 7W39 7W3A 7W3B 7W3C 7W3F 7W3G 7W3H 7W3I 7W3J 7W3K 7W3M 8CVT 8JRI 8JRT 8JTI 8K0G 8USB 8USC 9E8G 9E8H 9E8I 9E8J 9E8K 9E8L 9E8N 9E8O 9E8Q
Enriched GO Terms of Interacting Partners?		Modification-dependent Protein Catabolic Process Proteolysis Involved In Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Protein Ubiquitination Proteasomal Protein Catabolic Process Protein Modification By Small Protein Conjugation Proteolysis Macromolecule Catabolic Process Post-translational Protein Modification Regulation Of Proteolysis Protein Catabolic Process Protein Modification Process Regulation Of Protein Catabolic Process Protein Metabolic Process Positive Regulation Of Proteolysis Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Catabolic Process Ubiquitin-protein Transferase Activity Regulation Of Proteasomal Protein Catabolic Process Ubiquitin Protein Ligase Activity Protein Polyubiquitination Positive Regulation Of Protein Metabolic Process Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Positive Regulation Of Catabolic Process Positive Regulation Of Protein Catabolic Process Regulation Of Ubiquitin-dependent Protein Catabolic Process Nucleus Cytosol Ubiquitin Protein Ligase Binding Positive Regulation Of Macromolecule Metabolic Process Nucleoplasm Positive Regulation Of Metabolic Process Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Proteasomal Protein Catabolic Process Regulation Of Primary Metabolic Process Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Enzyme Binding Proteasome Binding Cytoplasm Cellular Response To Stress Protein-folding Chaperone Binding Ubiquitin Binding Regulation Of Metabolic Process Negative Regulation Of Potassium Ion Export Across Plasma Membrane Protein Monoubiquitination Ubiquitin Ligase Complex Regulation Of Signal Transduction Protein Destabilization	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of RNA Metabolic Process Chromatin Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Protein Dimerization Activity Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Regulator Complex Negative Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription DNA-binding Transcription Factor Binding Positive Regulation Of Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Nucleus Negative Regulation Of Macromolecule Metabolic Process BHLH Transcription Factor Binding Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Metabolic Process Rhythmic Process Positive Regulation Of Metabolic Process Regulation Of Cell Differentiation Regulation Of Macromolecule Metabolic Process Nucleoplasm Histone Deacetylase Binding Regulation Of Developmental Process E-box Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Multicellular Organismal Process Negative Regulation Of Cell Differentiation Cell Differentiation Regulation Of Metabolic Process Circadian Rhythm Positive Regulation Of Cell Differentiation Cellular Developmental Process Transcription Cis-regulatory Region Binding Negative Regulation Of Developmental Process
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