PLSCR4 and KRT82

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PLSCR4	KRT82
Description		phospholipid scramblase 4	keratin 82
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Plasma Membrane Membrane	Cytosol Intermediate Filament Keratin Filament
	Molecular Function	Calcium Ion Binding Protein Binding SH3 Domain Binding Phospholipid Scramblase Activity Enzyme Binding CD4 Receptor Binding	Protein Binding Structural Constituent Of Skin Epidermis
	Biological Process	Plasma Membrane Phospholipid Scrambling Calcium Activated Phosphatidylserine Scrambling Calcium Activated Phosphatidylcholine Scrambling Cellular Response To Lipopolysaccharide	Keratinization Intermediate Filament Organization
Pathways			Keratinization Formation of the cornified envelope
Drugs
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) Lymphocyte count ( 32888494)	Change in glucose in response to thiazide diuretic treatment in hypertension ( 29523524)
Interacting Genes		63 interacting genes: ABHD17A ADAMTSL4 APLN ATP23 CES1 CFAP68 CLPP CRCT1 DAZAP2 DDIT4L EFEMP2 FCHO1 GATA1 HDHD3 HOXA1 INTS11 ITGB4 KLHL38 KPRP KRT82 KRTAP1-5 KRTAP10-8 KRTAP19-1 KRTAP19-5 KRTAP19-6 KRTAP19-7 KRTAP21-2 KRTAP3-1 KRTAP3-3 KRTAP4-12 KRTAP4-2 KRTAP6-1 KRTAP6-2 KRTAP6-3 KRTAP8-1 LCE1A LCE1C LCE2B LCE5A LPXN MTUS2 NID2 NOTCH2NLA OXER1 PCSK5 PLA2G10 PLSCR1 RAMAC RBP3 RBPMS RPS27A SLC15A2 SSC4D TEKT5 TENM4 TRIM42 TRIP13 TSPAN4 UBA52 UBB UBC YPEL3 ZNF34	15 interacting genes: COL8A1 HGS HOXA1 KRT15 KRT16 KRT19 KRT27 KRT31 KRT33B KRT34 KRT35 KRT36 KRT40 PLSCR4 VAC14
Entrez ID		57088	3888
HPRD ID		07401	03048
Ensembl ID		ENSG00000114698	ENSG00000161850
Uniprot IDs		E9PHR9 Q9NRQ2	Q9NSB4
PDB IDs		3Q5U
Enriched GO Terms of Interacting Partners?		Intermediate Filament Keratinization Keratin Filament Protein Tag Activity Endocytic Vesicle Membrane Epidermis Development Protein Binding Female Meiosis I	Structural Constituent Of Skin Epidermis Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Intermediate Filament Structural Molecule Activity Morphogenesis Of An Epithelium Epithelial Cell Differentiation Tissue Morphogenesis Supramolecular Fiber Organization Anatomical Structure Morphogenesis Cytoskeleton Organization Cytoskeleton Cell Differentiation Organelle Organization Structural Constituent Of Cytoskeleton Cellular Developmental Process Epidermis Development Extracellular Exosome Hair Cycle Developmental Process Cytosol Semicircular Canal Formation PAS Complex Collagen Type VIII Trimer Abducens Nerve Formation Optokinetic Behavior Terminal Web ESCRT-0 Complex Calcium Activated Phosphatidylserine Scrambling Tissue Development Phagocytic Vesicle Lumen Calcium Activated Phosphatidylcholine Scrambling Calcium Activated Phospholipid Scrambling
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