COQ9 and PLSCR2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		COQ9	PLSCR2
Description		coenzyme Q9	phospholipid scramblase 2
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Ubiquinone Biosynthesis Complex	Nucleus Nucleoplasm Endoplasmic Reticulum Plasma Membrane Membrane
	Molecular Function	Protein Binding Enzyme Activator Activity Lipid Binding Isoprenoid Binding Protein Homodimerization Activity	Calcium Ion Binding Protein Binding Phospholipid Scramblase Activity Metal Ion Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Ubiquinone Biosynthetic Process	Plasma Membrane Phospholipid Scrambling
Pathways		Ubiquinol biosynthesis
Drugs
Diseases		Coenzyme Q10 deficiency
GWAS			Hip circumference ( 28552196)
Interacting Genes		33 interacting genes: ACSF2 ACTL6B ADIPOQ ALDH18A1 ANO8 BMP10 CCL4L2 CLNK COQ4 COQ8A CTSA CTXN3 CYB561D2 CYBC1 EHHADH GALNT2 HMOX1 KIR2DL3 MGLL ORMDL1 PLSCR2 SCARF1 SLC13A1 STX3 TEX264 TMEM14C TMEM79 TMEM86A TNFRSF10C TRAF3IP3 TSPAN33 VSTM1 WFDC2	16 interacting genes: AQP1 BSND COQ9 EP300 FAM221B GNG13 HOXA1 LCE1A LCE3A LCE3E LCE5A LYPD1 OTX1 POU4F2 PSMD8 TMEM132D
Entrez ID		57017	57047
HPRD ID		13157	09621
Ensembl ID		ENSG00000088682	ENSG00000163746
Uniprot IDs		O75208	Q9NRY7
PDB IDs		4RHP 6AWL 6DEW 7SSP 7SSS
Enriched GO Terms of Interacting Partners?			Keratinization Tissue Development Epidermis Development Sensory Perception Nervous System Process Metanephric Descending Thin Limb Development Metanephric Proximal Straight Tubule Development Nitric Oxide Transmembrane Transporter Activity Metanephric Proximal Convoluted Tubule Segment 2 Development Behavioral Defense Response Peptidyl-lysine Propionylation Swimming Histone Lactyltransferase (CoA-dependent) Activity Peptidyl-lysine Butyrylation Peptidyl-lysine Crotonylation Histone H3K122 Acetyltransferase Activity Histone Butyryltransferase Activity Histone Crotonyltransferase Activity Sensory Perception Of Sound Sensory Perception Of Mechanical Stimulus Semicircular Canal Formation Diencephalon Morphogenesis Isoprenoid Binding Metanephric Glomerulus Vasculature Development Glycerol Transmembrane Transporter Activity Corticotropin Secretion System Process Histone H2B Acetyltransferase Activity Acetylation-dependent Protein Binding Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Protein Propionyltransferase Activity Histone H3K27 Acetyltransferase Activity Peptide Crotonyltransferase Activity Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Abducens Nerve Formation Optokinetic Behavior P53 Binding
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