JPH1 and TMEM65

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		JPH1	TMEM65
Description		junctophilin 1	transmembrane protein 65
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Membrane Sarcoplasmic Reticulum Z Disc Junctional Membrane Complex Sarcoplasmic Reticulum Membrane	Nucleolus Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Intercalated Disc Membrane
	Molecular Function	Protein Binding Structural Constituent Of Muscle	Protein Binding
	Biological Process	Muscle Organ Development Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Calcium Ion Transport Into Cytosol	Cardiac Ventricle Development Cardiac Conduction Regulation Of Cardiac Conduction
Pathways
Drugs
Diseases
GWAS		Carotid plaque burden (smoking interaction) ( 24954085) Uterine fibroids ( 28836065)	Fear of minor pain ( 28701861)
Interacting Genes		17 interacting genes: AQP6 EDDM3B EMP1 GPR42 HTATIP2 LEPROTL1 MEOX2 NAT8 PLP1 RSPH1 SLC16A13 STRIT1 TMEM120B TMEM65 TTN UACA UBC	33 interacting genes: ABHD16A AQP6 ARL13B CYB561 CYBRD1 EBP ERGIC3 FAM174A FAM209A GJA8 GPR42 HSD17B11 IGSF9 IL3RA JAGN1 JPH1 LMNA MSMO1 PDZK1IP1 PTGES PVR REEP4 RETREG3 SCN3B SLC10A6 SLC18A1 SLC35H1 SLC7A8 TIMMDC1 TMEM101 TMEM80 TMX2 ZFYVE27
Entrez ID		56704	157378
HPRD ID		07286	14102
Ensembl ID		ENSG00000104369	ENSG00000164983
Uniprot IDs		Q86VR1 Q9HDC5	Q6PI78
PDB IDs		7RW4
Enriched GO Terms of Interacting Partners?			Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum Organization Endoplasmic Reticulum Tubular Network Endoplasmic Reticulum Tubular Network Organization Ascorbate Homeostasis Transmembrane Monodehydroascorbate Reductase Activity Endoplasmic Reticulum Transmembrane Transport Protein Binding
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