PSD and HEXD

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		PSD	HEXD
Description		pleckstrin and Sec7 domain containing	hexosaminidase D
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Postsynaptic Density Membrane Cleavage Furrow Ruffle Membrane Cell Projection Dendritic Spine Postsynaptic Density, Intracellular Component	Nucleus Cytoplasm Extracellular Vesicle
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Phospholipid Binding	Hydrolase Activity, Hydrolyzing O-glycosyl Compounds Beta-N-acetylhexosaminidase Activity Hexosaminidase Activity Hydrolase Activity Hydrolase Activity, Acting On Glycosyl Bonds
	Biological Process	Signal Transduction Neuron Projection Development Regulation Of ARF Protein Signal Transduction	Carbohydrate Metabolic Process
Pathways
Drugs
Diseases
GWAS		Apolipoprotein B levels ( 32203549) Prostate cancer ( 23535732) Refractive error ( 32231278) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: GLRA2 GMFG GNB5 HEXD RAB40C	9 interacting genes: ADPRS C7orf25 EEF1D GDPD2 GLRX3 PRKN PSD RILPL2 TUBB3
Entrez ID		5662	284004
HPRD ID		09085	08677
Ensembl ID		ENSG00000059915	ENSG00000169660
Uniprot IDs		A5PKW4 Q86YI3	Q8WVB3
PDB IDs
Enriched GO Terms of Interacting Partners?		Glycine-gated Chloride Ion Channel Activity Extracellularly Glycine-gated Chloride Channel Activity Actin Filament Debranching GTPase Activator Complex G-protein Gamma-subunit Binding Light Adaption Dark Adaptation Hexosaminidase Activity Transmitter-gated Monoatomic Ion Channel Activity Beta-N-acetylhexosaminidase Activity Excitatory Extracellular Ligand-gated Monoatomic Ion Channel Activity Postsynaptic Membrane Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation Glycinergic Synapse Negative Regulation Of Actin Nucleation Negative Regulation Of Voltage-gated Calcium Channel Activity Cell Tip Glycine Binding Cellular Response To Ethanol Actin Filament Severing Arp2/3 Complex Binding Regulation Of Voltage-gated Calcium Channel Activity GTPase Activity Response To Light Intensity Cul5-RING Ubiquitin Ligase Complex Lipid Droplet Formation Negative Regulation Of Focal Adhesion Assembly Cellular Response To Zinc Ion Parallel Fiber To Purkinje Cell Synapse G Protein-coupled Dopamine Receptor Signaling Pathway Regulation Of Arp2/3 Complex-mediated Actin Nucleation Negative Regulation Of Transporter Activity Hydrolase Activity, Hydrolyzing O-glycosyl Compounds	Heat Shock Protein Binding Parkin-FBXW7-Cul1 Ubiquitin Ligase Complex Regulation Of Necroptotic Process Positive Regulation Of Retrograde Transport, Endosome To Golgi Negative Regulation Of Glucokinase Activity Regulation Protein Catabolic Process At Presynapse Regulation Of Programmed Necrotic Cell Death Negative Regulation Of Intralumenal Vesicle Formation Mitochondrion To Lysosome Vesicle-mediated Transport Mitochondrion-derived Vesicle F-box Domain Binding Positive Regulation Of Protein Linear Polyubiquitination Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Hydrogen Sulfide Negative Regulation Of Spontaneous Neurotransmitter Secretion Response To Curcumin Netrin Receptor Binding Glycerophosphoinositol Inositolphosphodiesterase Activity Poly(ADP-ribose) Glycohydrolase Activity ADP-ribosylserine Hydrolase Activity Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation Protein Transport From Ciliary Membrane To Plasma Membrane Eukaryotic Translation Elongation Factor 1 Complex Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Mitochondrial Fusion Cellular Response To L-glutamine Response To Hydrogen Sulfide Negative Regulation Of Exosomal Secretion Glycerophosphodiester Phosphodiesterase Activity O-acetyl-ADP-ribose Deacetylase Activity Cytoplasmic Translational Elongation Lewy Body Regulation Of Spontaneous Synaptic Transmission Type 2 Mitophagy Dopamine Uptake Involved In Synaptic Transmission Negative Regulation Of Mitochondrial Fission Regulation Of Endosome Organization Positive Regulation Of Mitochondrial Membrane Potential Aggresome Assembly Positive Regulation Of Neurotransmitter Uptake Cell Projection Regulation Of Synaptic Vesicle Transport Dorsal Root Ganglion Development Response To Superoxide Protein De-ADP-ribosylation Free Ubiquitin Chain Polymerization Cellular Response To Dopamine Negative Regulation Of Mitochondrial Fusion Negative Regulation Of Neurotransmitter Secretion
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?