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DIABLO and ARL6IP1
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid, two hybrid)
DIABLO
ARL6IP1
Description
diablo IAP-binding mitochondrial protein
ARL6 interacting reticulophagy regulator 1
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Mitochondrion
Mitochondrial Intermembrane Space
Cytosol
Cytoplasmic Side Of Plasma Membrane
CD40 Receptor Complex
Cytoplasm
Endoplasmic Reticulum
Sec61 Translocon Complex
Endoplasmic Reticulum Membrane
Cytosol
Endomembrane System
Membrane
Endoplasmic Reticulum Tubular Network
Molecular Function
Protein Binding
Protein Binding
Identical Protein Binding
Biological Process
Apoptotic Process
Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress
Positive Regulation Of Apoptotic Process
Neuron Apoptotic Process
Apoptotic Signaling Pathway
Intrinsic Apoptotic Signaling Pathway
Positive Regulation Of L-glutamate Import Across Plasma Membrane
Cotranslational Protein Targeting To Membrane
Apoptotic Process
Negative Regulation Of Apoptotic Process
Endoplasmic Reticulum Tubular Network Formation
Regulation Of Endoplasmic Reticulum Tubular Network Organization
Endoplasmic Reticulum Tubular Network Membrane Organization
Pathways
Release of apoptotic factors from the mitochondria
SMAC (DIABLO) binds to IAPs
SMAC (DIABLO) binds to IAPs
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes
SMAC, XIAP-regulated apoptotic response
Regulation of the apoptosome activity
Drugs
Phenethyl Isothiocyanate
Diseases
GWAS
A body shape index (
34021172
)
Waist-hip index (
34021172
)
Waist-to-hip ratio adjusted for BMI (
34021172
)
Caffeine consumption from coffee or tea (
33287642
)
Refractive error (
32231278
)
Interacting Genes
46 interacting genes:
AGTRAP
APOC2
APOC4
AREL1
ARL6IP1
ARNT
BEX3
BIRC2
BIRC3
BIRC5
BIRC6
BIRC7
CASP9
CDC34
CMTM4
DERL2
DGAT2L6
DHRS1
E2F1
EEF1A1
FADS6
FKBP7
HSD17B13
HSFX1
HTRA2
LTBR
MAML2
MICOS13
MPC2
NR4A1
RHBDD2
RMDN2
SBNO1
SEC22A
SFT2D1
SLC17A9
SLC25A47
SLC66A2
STMN4
SYP
TIMMDC1
UBC
UBE2K
UFM1
XIAP
ZNF746
78 interacting genes:
ACSF2
AQP6
ARL4D
ARL6
BCL2L13
C19orf18
CERT1
DIABLO
DRC4
EHD3
EMP1
F2RL1
FBXW7
FDFT1
FXR2
GAD2
GOLPH3
GOLPH3L
GORASP2
GPR151
GPR152
HGS
HMGCL
HSD17B13
INPP5K
LMNA
MCEMP1
MGST3
MIEF2
MTERF3
MYG1
NAPB
NDRG4
NTAQ1
NUDT3
PAM16
PBX3
PICK1
PTPN9
RAB33A
REEP6
RETREG3
RNF5
SDCBP
SENP2
SHISA5
SHMT2
SLC10A6
SLC13A1
SLC35H1
SLC61A1
SLC71A2
SNX1
SNX10
SNX11
SNX12
SNX15
SNX2
SNX3
SNX4
SNX8
SPG21
STARD4
SUCLA2
TARS2
TFAM
TMED8
TMEM14B
TMEM248
TMEM258
TUFM
UBE2I
VMA21
WDFY2
WIPI2
YIPF4
ZFYVE21
ZNF391
Entrez ID
56616
23204
HPRD ID
05560
09641
Ensembl ID
ENSG00000184047
ENSG00000170540
Uniprot IDs
A0A0S2Z5P6
A0A0S2Z5U7
K7X1S0
Q502X2
Q9NR28
Q15041
PDB IDs
1FEW
1G3F
1G73
1OXQ
1TW6
1XB0
1XB1
3D9U
3UIH
3UIJ
4TX5
6JX6
8ATO
8AUW
8E2I
8E2J
Enriched GO Terms of Interacting Partners
?
Cysteine-type Endopeptidase Inhibitor Activity Involved In Apoptotic Process
Cell Death
Apoptotic Process
Programmed Cell Death
Ubiquitin-protein Transferase Activity
Cysteine-type Endopeptidase Inhibitor Activity
Regulation Of Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Regulation Of Apoptotic Process
Regulation Of Programmed Cell Death
Positive Regulation Of Post-translational Protein Modification
Regulation Of Post-translational Protein Modification
Cellular Response To Interferon-beta
Macromolecule Catabolic Process
Negative Regulation Of Apoptotic Process
Protein Modification By Small Protein Conjugation
Ubiquitin Conjugating Enzyme Activity
Negative Regulation Of Programmed Cell Death
Response To Interferon-beta
Regulation Of Protein Ubiquitination
Positive Regulation Of Protein Ubiquitination
Protein Ubiquitination
Signal Recognition Particle Binding
Peptidase Inhibitor Activity
Post-translational Protein Modification
Ubiquitin Protein Ligase Activity
CD40 Receptor Complex
Proteolysis Involved In Protein Catabolic Process
Positive Regulation Of Protein Modification Process
Identical Protein Binding
Canonical NF-kappaB Signal Transduction
Organophosphate Ester Transport
Regulation Of Inflammatory Response
Regulation Of Tumor Necrosis Factor-mediated Signaling Pathway
Protein Polyubiquitination
Proteolysis
Positive Regulation Of Protein Polyubiquitination
Response To Hypoxia
Negative Regulation Of Necroptotic Process
Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage
Protein Catabolic Process
Regulation Of RIG-I Signaling Pathway
Very-low-density Lipoprotein Particle
Negative Regulation Of Programmed Necrotic Cell Death
Response To Decreased Oxygen Levels
Protein Binding
Positive Regulation Of Execution Phase Of Apoptosis
Regulation Of Protein Modification Process
Regulation Of Cytoplasmic Pattern Recognition Receptor Signaling Pathway
Regulation Of Canonical NF-kappaB Signal Transduction
Nucleotide Transmembrane Transport
Lipid Binding
Phosphatidylinositol Binding
Cellular Localization
Establishment Of Protein Localization
Retromer Complex
Intracellular Transport
Protein Transport
Membrane
Establishment Of Localization In Cell
Leptin Receptor Binding
Localization Within Membrane
Intracellular Protein Transport
Early Endosome To Golgi Transport
Intracellular Protein Localization
Vesicle-mediated Transport To The Plasma Membrane
Golgi Vesicle Transport
Retrograde Transport, Endosome To Golgi
Endosome
Phosphatidylinositol-4-phosphate Binding
Transferrin Receptor Binding
Negative Regulation Of Early Endosome To Late Endosome Transport
Endosomal Transport
Endocytic Recycling
Cytosolic Transport
Early Endosome Membrane
Phosphatidylinositol-3-phosphate Binding
Protein Targeting To Golgi Apparatus
Protein Binding
Mitochondrial Matrix
Early Endosome
Retromer, Tubulation Complex
Golgi Vesicle Budding
Cargo Adaptor Activity
Establishment Of Protein Localization To Plasma Membrane
Insulin Receptor Binding
Vesicle-mediated Transport
Organelle Organization
Phosphatidylinositol Phosphate Binding
Late Endosome To Golgi Transport
Succinate Metabolic Process
Lamellipodium Morphogenesis
Epidermal Growth Factor Receptor Binding
Vesicle Budding From Membrane
Protein Localization To Membrane
Vesicle Organization
Positive Regulation Of Exocytosis
Regulation Of Establishment Of Protein Localization
Membrane Organization
Golgi Cisterna
Regulation Of Protein Localization
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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