NDUFA12 and ZNF768

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		NDUFA12	ZNF768
Description		NADH:ubiquinone oxidoreductase subunit A12	zinc finger protein 768
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I	Nucleus Chromosome
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Aerobic Respiration Mitochondrial ATP Synthesis Coupled Electron Transport Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II
Pathways		Respiratory electron transport Complex I biogenesis
Drugs		NADH
Diseases
GWAS		Brain morphology (MOSTest) ( 32665545) Chromosomal aberration frequency (chromosome type) ( 31586183) Coronary artery disease ( 29212778 32469254) Heel bone mineral density x serum urate levels interaction ( 34046847) Myocardial infarction ( 33532862)
Interacting Genes		4 interacting genes: MYO15B SYT4 TMED8 ZNF768	17 interacting genes: CLK2 DCTPP1 EFEMP2 EMG1 KRTAP10-1 NDUFA12 NSG2 OGT PIN1 SDCBP TNNT1 ZNF250 ZNF277 ZNF330 ZNF417 ZNF648 ZNF835
Entrez ID		55967	79724
HPRD ID		16781	08671
Ensembl ID		ENSG00000184752	ENSG00000169957
Uniprot IDs		Q9UI09	H3BS42 Q9H5H4
PDB IDs		5XTB 5XTD 5XTH 5XTI
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Dense Core Granule Exocytosis Negative Regulation Of Retrograde Trans-synaptic Signaling By Neuropeptide Regulation Of Postsynaptic Dense Core Vesicle Exocytosis Negative Regulation Of Short-term Neuronal Synaptic Plasticity Dense Core Granule Membrane Regulation Of Trans-synaptic Signaling By BDNF, Modulating Synaptic Transmission Regulation Of Dense Core Granule Exocytosis Neuronal Dense Core Vesicle Membrane Negative Regulation Of Synaptic Vesicle Exocytosis Negative Regulation Of Calcium Ion-dependent Exocytosis Microvesicle Dense Core Granule Cytoskeletal Transport Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Calcium-dependent Activation Of Synaptic Vesicle Fusion Somatodendritic Compartment Secretory Granule Localization Negative Regulation Of Catecholamine Secretion Dense Core Granule Positive Regulation Of Calcium Ion-dependent Exocytosis Neuronal Dense Core Vesicle Positive Regulation Of Dendrite Extension Calcium Ion Sensor Activity Astrocyte Projection Regulation Of Glutamate Secretion Positive Regulation Of Glutamate Secretion Positive Regulation Of Amino Acid Transport Regulation Of Short-term Neuronal Synaptic Plasticity Positive Regulation Of Vesicle Fusion Regulation Of Dopamine Secretion Exocytic Vesicle Regulation Of Vesicle Fusion Regulation Of Catecholamine Secretion Regulation Of Calcium Ion-dependent Exocytosis Neurotransmitter Secretion Negative Regulation Of Exocytosis Positive Regulation Of Regulated Secretory Pathway Calcium-dependent Phospholipid Binding Regulation Of Synaptic Vesicle Exocytosis
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