MAPK1 and HIF1A

Number of citations of the paper that reports this interaction (PubMedID 16954218)
0

Data Source:
BioGRID (enzymatic study)

		MAPK1	HIF1A
Description		mitogen-activated protein kinase 1	hypoxia inducible factor 1 subunit alpha
Image
GO Annotations	Cellular Component	Extracellular Region Nucleus Nucleoplasm Cytoplasm Mitochondrion Early Endosome Late Endosome Endoplasmic Reticulum Lumen Golgi Apparatus Centrosome Spindle Cytosol Cytoskeleton Plasma Membrane Caveola Focal Adhesion Cilium Microtubule Cytoskeleton Membrane Pseudopodium Azurophil Granule Lumen Ciliary Basal Body Synapse Anchoring Junction Mitotic Spindle Ficolin-1-rich Granule Lumen	Chromatin Euchromatin Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Cytosol Nuclear Body Nuclear Speck Motile Cilium Protein-containing Complex RNA Polymerase II Transcription Regulator Complex Axon Cytoplasm
	Molecular Function	Nucleotide Binding Phosphotyrosine Residue Binding DNA Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity MAP Kinase Activity Protein Binding ATP Binding RNA Polymerase II CTD Heptapeptide Repeat Kinase Activity Kinase Activity Transferase Activity Phosphatase Binding Identical Protein Binding Protein Serine Kinase Activity	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity DNA-binding Transcription Repressor Activity Transcription Corepressor Binding Transcription Coactivator Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific P53 Binding DNA Binding DNA-binding Transcription Factor Activity Protein Binding Nuclear Receptor Binding Enzyme Binding Protein Kinase Binding Protein Domain Specific Binding Ubiquitin Protein Ligase Binding Histone Deacetylase Binding Sequence-specific DNA Binding Protein Heterodimerization Activity Protein Dimerization Activity Hsp90 Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding E-box Binding Transcription Regulator Activator Activity
	Biological Process	MAPK Cascade Regulation Of Transcription By RNA Polymerase II Protein Phosphorylation Apoptotic Process Chemotaxis DNA Damage Response Signal Transduction Cell Surface Receptor Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Chemical Synaptic Transmission Heart Development Learning Or Memory Insulin Receptor Signaling Pathway Animal Organ Morphogenesis Positive Regulation Of Macrophage Chemotaxis Positive Regulation Of Peptidyl-threonine Phosphorylation Neural Crest Cell Development Schwann Cell Development Peptidyl-threonine Phosphorylation Cytosine Metabolic Process Regulation Of Ossification Regulation Of Cellular PH Thyroid Gland Development Regulation Of Protein Stability Lipopolysaccharide-mediated Signaling Pathway Positive Regulation Of Telomere Maintenance Response To Lipopolysaccharide Regulation Of Stress-activated MAPK Cascade Mammary Gland Epithelial Cell Proliferation Cellular Response To Amino Acid Starvation Response To Nicotine Intracellular Signal Transduction ERBB Signaling Pathway ERBB2-ERBB3 Signaling Pathway Outer Ear Morphogenesis Myelination Response To Exogenous DsRNA Positive Regulation Of Cholesterol Biosynthetic Process Negative Regulation Of Cell Differentiation Insulin-like Growth Factor Receptor Signaling Pathway Thymus Development T Cell Receptor Signaling Pathway B Cell Receptor Signaling Pathway Stress-activated MAPK Cascade Regulation Of Cytoskeleton Organization Bergmann Glial Cell Differentiation Long-term Synaptic Potentiation Face Development Lung Morphogenesis Trachea Formation Labyrinthine Layer Blood Vessel Development Cardiac Neural Crest Cell Development Involved In Heart Development Interleukin-34-mediated Signaling Pathway Chemokine-mediated Signaling Pathway ERK1 And ERK2 Cascade Response To Epidermal Growth Factor Cellular Response To Tumor Necrosis Factor Caveolin-mediated Endocytosis Regulation Of Golgi Inheritance Positive Regulation Of Macrophage Proliferation Positive Regulation Of Neuroinflammatory Response Regulation Of Early Endosome To Late Endosome Transport	Response To Reactive Oxygen Species Angiogenesis Blood Vessel Development Response To Hypoxia Intracellular Glucose Homeostasis Neural Crest Cell Migration Epithelial To Mesenchymal Transition Embryonic Placenta Development B-1 B Cell Homeostasis Positive Regulation Of Endothelial Cell Proliferation Vasculature Development Heart Looping Positive Regulation Of Neuroblast Proliferation Chondrocyte Differentiation Glandular Epithelial Cell Differentiation Glandular Epithelial Cell Maturation Connective Tissue Replacement Involved In Inflammatory Response Wound Healing Outflow Tract Morphogenesis Cardiac Ventricle Morphogenesis Lactate Metabolic Process Regulation Of Glycolytic Process Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Intracellular Iron Ion Homeostasis Apoptotic Process Signal Transduction Neuroblast Proliferation Lactation Visual Learning Response To Iron Ion Regulation Of Gene Expression Vascular Endothelial Growth Factor Production Positive Regulation Of Vascular Endothelial Growth Factor Production Positive Regulation Of Gene Expression Negative Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Response To Muscle Activity Positive Regulation Of Macroautophagy Axonal Transport Of Mitochondrion Neural Fold Elevation Formation Cerebral Cortex Development Cell Differentiation Negative Regulation Of Ossification Bone Mineralization Negative Regulation Of Bone Mineralization Positive Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway TOR Signaling Negative Regulation Of TOR Signaling Intracellular Oxygen Homeostasis Positive Regulation Of Chemokine Production Regulation Of Transforming Growth Factor Beta2 Production Collagen Metabolic Process Cellular Response To Oxidative Stress Embryonic Hemopoiesis Insulin Secretion Involved In Cellular Response To Glucose Stimulus Positive Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Cell Population Proliferation Hemoglobin Biosynthetic Process Glucose Homeostasis Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Erythrocyte Differentiation Positive Regulation Of Angiogenesis Positive Regulation Of Glycolytic Process Positive Regulation Of DNA-templated Transcription Negative Regulation Of Growth Positive Regulation Of Transcription By RNA Polymerase II Muscle Cell Cellular Homeostasis Positive Regulation Of Hormone Biosynthetic Process Blood Vessel Morphogenesis Digestive Tract Morphogenesis Camera-type Eye Morphogenesis Cartilage Development Neuron Apoptotic Process Elastin Metabolic Process Intestinal Epithelial Cell Maturation Epithelial Cell Differentiation Involved In Mammary Gland Alveolus Development Iris Morphogenesis Retina Vasculature Development In Camera-type Eye Positive Regulation Of Chemokine-mediated Signaling Pathway Regulation Of Thymocyte Apoptotic Process Negative Regulation Of Thymocyte Apoptotic Process Cellular Response To Interleukin-1 Cellular Response To Hypoxia Dopaminergic Neuron Differentiation Mesenchymal Cell Apoptotic Process Hypoxia-inducible Factor-1alpha Signaling Pathway Cellular Response To Virus Positive Regulation Of Cytokine Production Involved In Inflammatory Response Negative Regulation Of MiRNA Transcription Positive Regulation Of MiRNA Transcription Negative Regulation Of Oxidative Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Protein Neddylation Negative Regulation Of Mesenchymal Cell Apoptotic Process
Pathways		phospho-PLA2 pathway RAF-independent MAPK1/3 activation MAPK1 (ERK2) activation Signaling by NODAL Spry regulation of FGF signaling Signaling by Activin Golgi Cisternae Pericentriolar Stack Reorganization Frs2-mediated activation ERK/MAPK targets ERK/MAPK targets ERKs are inactivated Regulation of actin dynamics for phagocytic cup formation Downregulation of SMAD2/3:SMAD4 transcriptional activity SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription Oxidative Stress Induced Senescence Senescence-Associated Secretory Phenotype (SASP) Oncogene Induced Senescence Oncogene Induced Senescence FCERI mediated MAPK activation Regulation of HSF1-mediated heat shock response NCAM signaling for neurite out-growth Recycling pathway of L1 RSK activation Signal transduction by L1 Activation of the AP-1 family of transcription factors Thrombin signalling through proteinase activated receptors (PARs) Negative regulation of FGFR1 signaling Negative regulation of FGFR2 signaling Negative regulation of FGFR3 signaling Negative regulation of FGFR4 signaling RHO GTPases Activate WASPs and WAVEs RHO GTPases Activate NADPH Oxidases RAF/MAP kinase cascade MAP2K and MAPK activation Negative feedback regulation of MAPK pathway Negative regulation of MAPK pathway Neutrophil degranulation Signaling by moderate kinase activity BRAF mutants Signaling by high-kinase activity BRAF mutants Signaling by BRAF and RAF1 fusions Paradoxical activation of RAF signaling by kinase inactive BRAF PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Signal attenuation Interferon gamma signaling Advanced glycosylation endproduct receptor signaling Gastrin-CREB signalling pathway via PKC and MAPK ESR-mediated signaling RUNX2 regulates osteoblast differentiation Regulation of PTEN gene transcription Regulation of the apoptosome activity Estrogen-stimulated signaling through PRKCZ Estrogen-dependent nuclear events downstream of ESR-membrane signaling Estrogen-dependent nuclear events downstream of ESR-membrane signaling Suppression of apoptosis Signaling downstream of RAS mutants Signaling by MAP2K mutants Signaling by MAPK mutants Signaling by RAF1 mutants FCGR3A-mediated phagocytosis Nuclear events stimulated by ALK signaling in cancer IFNG signaling activates MAPKs Negative Regulation of CDH1 Gene Transcription NPAS4 regulates expression of target genes NPAS4 regulates expression of target genes Growth hormone receptor signaling Signaling by LTK in cancer Transcriptional and post-translational regulation of MITF-M expression and activity	Regulation of gene expression by Hypoxia-inducible Factor Cellular response to hypoxia Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha NOTCH1 Intracellular Domain Regulates Transcription Ub-specific processing proteases Interleukin-4 and Interleukin-13 signaling PTK6 Expression PTK6 promotes HIF1A stabilization Neddylation STAT3 nuclear events downstream of ALK signaling Regulation of PD-L1(CD274) transcription
Drugs		Acetylsalicylic acid Minocycline Arsenic trioxide Olomoucine Phosphonothreonine Colforsin Purvalanol SB220025 Seliciclib Perifosine N,N-DIMETHYL-4-(4-PHENYL-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE N-BENZYL-4-[4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL]-1H-PYRROLE-2-CARBOXAMIDE (S)-N-(1-(3-CHLORO-4-FLUOROPHENYL)-2-HYDROXYETHYL)-4-(4-(3-CHLOROPHENYL)-1H-PYRAZOL-3-YL)-1H-PYRROLE-2-CARBOXAMIDE (3R,5Z,8S,9S,11E)-8,9,16-TRIHYDROXY-14-METHOXY-3-METHYL-3,4,9,10-TETRAHYDRO-1H-2-BENZOXACYCLOTETRADECINE-1,7(8H)-DIONE 5-(2-PHENYLPYRAZOLO[1,5-A]PYRIDIN-3-YL)-1H-PYRAZOLO[3,4-C]PYRIDAZIN-3-AMINE Hypothemycin [4-({5-(AMINOCARBONYL)-4-[(3-METHYLPHENYL)AMINO]PYRIMIDIN-2-YL}AMINO)PHENYL]ACETIC ACID 4-[4-(4-Fluorophenyl)-2-[4-[(R)-methylsulfinyl]phenyl]-1H-imidazol-5-yl]pyridine Turpentine Ulixertinib	Carvedilol Hydralazine 2-Methoxyestradiol ENMD-1198 PX-478 FG-2216 Vadadustat
Diseases
GWAS		Bipolar disorder ( 31043756) Body size at age 10 ( 32376654) Inflammatory bowel disease ( 23128233) Multiple sclerosis ( 21833088 24076602 31604244) Serum interleukin-6 concentration in active individuals ( 32928877) Superior parietal cortex volume ( 31530798)
Interacting Genes		255 interacting genes: AR ARRB1 ARRB2 ATF2 ATM ATP1A1 BANP BCL2 BCL3 BCL6 BRAF BTRC C1QBP CACYBP CAD CALCOCO1 CAPN2 CASP8 CASP9 CAV1 CD19 CDC25C CDX2 CEBPA CEBPB CEP55 CHN1 CITED2 CMTM3 COPS6 CREBBP CRP CSNK2A1 CTNND1 CTSD CUEDC2 DAPK1 DUSP1 DUSP16 DUSP2 DUSP3 DUSP4 DUSP5 DUSP6 DUSP7 DUSP9 DYRK1B EGFR EGLN3 EIF4EBP1 ELK1 ELK4 ENAH EP300 EPOR ERF ESR1 ESR2 ETS1 FCGR2B FHL3 FOS FOXO3 FRS2 FRS3 GAB1 GAB2 GABRR1 GAPDH GATA1 GATA2 GATA4 GJA1 GMFB GNPTAB GORASP2 GRB10 GRB2 GSK3B HDAC4 HDAC6 HERC3 HIF1A HMGA1 HNF4A HOMEZ HSF1 HSF4 HSP90AA1 ID2 IER3 IFI35 IFNAR1 ILF3 IQGAP1 IRS1 ITGB6 JUND KARS1 KDR KHDRBS1 KLF11 KRT8 KSR1 KSR2 LAMTOR3 LCK LIFR LIPE LRPAP1 LRRC4 LZTS2 MAFA MAP2K1 MAP2K2 MAP2K4 MAP2K6 MAP2K7 MAP3K1 MAP3K10 MAPK14 MAPK8 MAPKAPK5 MAPT MBP MCL1 MDFI ME1 METAP2 METTL3 MITF MKNK1 MKNK2 MSX2 MTIF3 MTPN MYB MYC NCOA1 NCOA3 NDE1 NEFH NEK2 NGFR NKX2-1 NOXA1 NR3C1 NR4A1 NR4A2 NR5A1 NRL NTRK3 NUP153 PAK1 PAK2 PAX5 PDE4D PEA15 PEBP1 PKM PLA2G4A PLAGL2 PLAT PLCB1 PLEKHM1 PLK3 POLR2G PPARA PPARG PPP1CA PPP1R18 PPP1R9B PPP2CA PPP2R5B PPP2R5C PRDX6 PRKCD PRKCE PRKCZ PRPSAP1 PSMA1 PTPN1 PTPN5 PTPN7 PTPRC PTPRE PTPRH PTPRR PXN RAF1 RB1 REST RET RGS19 RNF216 RNF8 RPS6KA1 RPS6KA2 RPS6KA3 RPS6KA4 RPS6KB1 RPTOR RUNX1 RXRA SCNN1G SH2D3C SHANK3 SHC1 SLC9A1 SMAD1 SMAD2 SMAD3 SMAD4 SNCA SNCG SORBS3 SOS1 SOX10 SP1 SREBF1 SREBF2 STAT3 STAT5A STAT5B STXBP1 STYX SUPT20H TCF3 TFCP2 TGIF1 TH TIAL1 TLE5 TNFRSF1A TNFRSF25 TNFSF11 TNIP1 TNIP2 TNKS2 TOB1 TOP2A TP53 TPR TSC2 TTN TXNIP UBE3A UBR5 UBTF VAV1 VDR YBX1 YBX3 ZBTB42 ZFP36	133 interacting genes: AKT1 APEX1 AR ARNT ARNT2 ATM AURKA BAP1 BMAL1 BNIP3 CASR CCND2 CDC34 CDK4 CDK6 CDKN2A CDKN2B CHD4 CITED2 COPS5 CREB3L1 CREBBP CSNK1D CSNK2A1 CTNNB1 DAP3 E2F7 EAF2 EGLN1 EGLN2 EGLN3 EIF5A2 EP300 EPHA2 EPO ESRRA ESRRB ESRRG ETV4 F12 FBXL16 FBXO8 FGFR4 FZR1 GATA3 GLIS2 HDAC1 HDAC2 HDAC3 HDAC5 HIF1A-AS2 HIF1AN HIF3A HNF4A HSP90AA1 IKBKG ISG15 JUN KPNA1 KPNA3 KPNA4 KPNA5 KPNA6 L3MBTL3 LATS2 LINC01139 LRRK2 MAFG MAFK MAP2K3 MAP2K5 MAPK1 MAPK3 MAX MCL1 MCM7 MDM2 MTA1 MYC NAA10 NAA11 NBN NCOA1 NCOA2 NDN NEDD8 NF2 NQO1 NR4A1 OS9 PER1 PGK1 PKM PLD1 PLD2 PLK3 PPP1R13L PRKACA PSMA7 PTBP1 PTK6 RACGAP1 RACK1 RB1 RORA RUNX2 RWDD3 SAT1 SEPTIN9 SIRT2 SMAD3 SNHG11 SP1 SSX4 STAT3 STK11 SUCO SUMO1 TEAD2 TP53 TSGA10 UBE2D1 UBE2I UBE3B USP19 USP20 USP28 VBP1 VEGFA VHL VHLL VRK1 ZC3H12A
Entrez ID		5594	3091
HPRD ID		01496	04517
Ensembl ID		ENSG00000100030	ENSG00000100644
Uniprot IDs		P28482 Q1HBJ4 Q499G7	D0VY79 Q16665
PDB IDs		1PME 1TVO 1WZY 2OJG 2OJI 2OJJ 2Y9Q 3D42 3D44 3I5Z 3I60 3SA0 3TEI 3W55 4FMQ 4FUX 4FUY 4FV0 4FV1 4FV2 4FV3 4FV4 4FV5 4FV6 4FV7 4FV8 4FV9 4G6N 4G6O 4H3P 4H3Q 4IZ5 4IZ7 4IZA 4N0S 4NIF 4O6E 4QP1 4QP2 4QP3 4QP4 4QP6 4QP7 4QP8 4QP9 4QPA 4QTA 4QTE 4XJ0 4ZXT 4ZZM 4ZZN 4ZZO 5AX3 5BUE 5BUI 5BUJ 5BVD 5BVE 5BVF 5K4I 5LCJ 5LCK 5NGU 5NHF 5NHH 5NHJ 5NHL 5NHO 5NHP 5NHV 5V60 5V61 5V62 5WP1 6D5Y 6DMG 6G54 6G8X 6G91 6G92 6G93 6G97 6G9A 6G9D 6G9H 6G9J 6G9K 6G9M 6G9N 6GDM 6GDQ 6GE0 6GJB 6GJD 6NBS 6OPG 6OPH 6OPI 6Q7K 6Q7S 6Q7T 6QA1 6QA3 6QA4 6QAG 6QAH 6QAL 6QAQ 6QAW 6RQ4 6SLG 7AUV 7E73 7E75 7NQQ 7NQW 7NR3 7NR5 7NR8 7NR9 7OPM 7W5O 7X4U 7XC1 8AO2 8AO3 8AO4 8AO5 8AO6 8AO7 8AO8 8AO9 8AOA 8AOB 8AOC 8AOD 8AOE 8AOF 8AOG 8AOH 8AOI 8AOJ 8PSR 8PST 8PSW 8PSY 8PT0 8PT1 8PT3 8PT5 8PVU 8R5F 8U8J 8U8K 8ZJV	1H2K 1H2L 1H2M 1L3E 1L8C 1LM8 1LQB 2ILM 3HQR 3HQU 4AJY 4H6J 5JWP 5L9B 5L9V 5LA9 5LAS 6GFX 6GMR 6YW3 7LVS 7QGS 8HE0 8HE3
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Signal Transduction Regulation Of Cell Communication Regulation Of Signal Transduction Regulation Of Signaling Positive Regulation Of Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Apoptotic Process Regulation Of Programmed Cell Death MAPK Cascade Regulation Of Intracellular Signal Transduction Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Intracellular Signaling Cassette Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription By RNA Polymerase II Cytosol Regulation Of Multicellular Organismal Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Response To Hormone Cytoplasm Nucleus Negative Regulation Of Metabolic Process Response To Lipid Nucleoplasm Positive Regulation Of Multicellular Organismal Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Cell Surface Receptor Signaling Pathway Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Signaling Negative Regulation Of Cell Communication Cellular Response To Oxygen-containing Compound Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process Positive Regulation Of Signal Transduction DNA-binding Transcription Factor Activity	Nucleoplasm Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Transcription By RNA Polymerase II Regulation Of Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Biosynthetic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Positive Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Response To Stress Regulation Of Gene Expression Regulation Of RNA Metabolic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Transcription By RNA Polymerase II RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Metabolic Process Intracellular Signal Transduction Negative Regulation Of Macromolecule Metabolic Process Regulation Of Protein Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Signal Transduction Positive Regulation Of Protein Metabolic Process DNA-binding Transcription Factor Binding Regulation Of Intracellular Signal Transduction Chromatin Regulation Of Developmental Process Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Response To Oxygen Levels Response To Stress Response To Decreased Oxygen Levels Regulation Of Cell Cycle Response To Hypoxia Regulation Of Signaling Regulation Of Cell Communication Protein Modification Process
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