LMO3 and FBLIM1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		LMO3	FBLIM1
Description		LIM domain only 3	filamin binding LIM protein 1
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm	Fibrillar Center Stress Fiber Cytoplasm Cytosol Cytoskeleton Focal Adhesion Cell Junction Anchoring Junction Cell Periphery
	Molecular Function	Transcription Coactivator Activity Protein Binding Metal Ion Binding DNA-binding Transcription Factor Binding	Protein Binding Filamin Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway	Cell Adhesion Regulation Of Cell Shape Regulation Of Integrin Activation Cell-cell Adhesion
Pathways			Cell-extracellular matrix interactions
Drugs
Diseases
GWAS		Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Chronotype ( 30696823) Household income (MTAG) ( 31844048) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Smoking initiation ( 33082346) Tourette syndrome ( 30818990) Worry too long after an embarrassing experience ( 29500382)	Alcoholic chronic pancreatitis ( 28754779) Cardiac Troponin-T levels ( 23247143) Gut microbiota (bacterial taxa) ( 27723756) Heel bone mineral density ( 30598549)
Interacting Genes		124 interacting genes: ABI2 ACTMAP AIMP2 AMIGO1 AMOTL2 AVPI1 BANP BCAS2 BEND5 BEND7 BHLHE40 BLZF1 CARD9 CARF CBY2 CCDC33 CCDC85B CCSER1 CDYL2 CEP170P1 CEP57 CEP57L1 CYSRT1 DCDC2 DVL2 DYRK1A FAM131C FBLIM1 FOS GABPB1 GMEB2 GOLGA2 GOLGA6L9 GPATCH2L HMBOX1 HNRNPC HNRNPH1 HNRNPM HOMEZ HSPB2 HSPB2-C11orf52 IKZF1 IL16 INCA1 ITSN1 KANK2 KCTD1 KIF2A KRABD4 KRT31 KRT38 KXD1 LDB1 LDB2 LIMS1 LNPK LPXN LZTS1 LZTS2 MAD1L1 MALSU1 MBD3 MBD3L1 MBIP MDFI MEIS3 MID2 MTUS2 MYOG MYOZ3 NBPF22P NDOR1 NFKBID NHLH2 NIF3L1 NTAQ1 NUTM1 PELO PHC2 PICK1 PNMA1 POU6F2 PPP1R13B PXN QRICH1 RALYL RCN1 RFC5 RFX6 RORA SAMD3 SH2B2 SHISA6 SLAIN1 SP4 TAX1BP1 TCP10L TEPSIN THAP1 TMEM121 TRAPPC2L TRIB3 TRIM23 TRIM54 TUFT1 USP54 VBP1 VMAC VPS28 WASHC1 WWOX ZBTB43 ZBTB8A ZBTB8B ZIM3 ZNF143 ZNF526 ZNF587 ZNF620 ZNF641 ZNF69 ZNF84 ZRANB1 ZSCAN9	11 interacting genes: ACTMAP ADAT3 FERMT2 FLNA FLNB H3-5 H3C1 KAZN LMO3 SHISA6 TRIM15
Entrez ID		55885	54751
HPRD ID		11832	09669
Ensembl ID		ENSG00000048540	ENSG00000162458
Uniprot IDs		Q8TAP4 Q9NYC6	Q8WUP2
PDB IDs			2K9U 2W0P 4P3W
Enriched GO Terms of Interacting Partners?		Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Identical Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process DNA Binding Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Microtubule Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding	Anchoring Junction Focal Adhesion Cell Cortex Actin Filament Binding Positive Regulation Of Substrate Adhesion-dependent Cell Spreading SMAD Binding Regulation Of Membrane Repolarization During Atrial Cardiac Muscle Cell Action Potential Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Actin Filament Bundle Assembly Cadherin Binding Protein Localization To Cell Junction Fc-gamma Receptor I Complex Binding Actin Binding Positive Regulation Of Protein Localization To Nucleus Tubulin Deacetylation Myb Complex Stress Fiber Structural Constituent Of Chromatin Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Negative Regulation Of Intracellular Transport Of Viral Material Mesodermal Cell Fate Determination Initiator Methionyl Aminopeptidase Activity Cysteine-type Aminopeptidase Activity Formation Of Radial Glial Scaffolds Establishment Of Sertoli Cell Barrier Nucleosome Asymmetric, Glutamatergic, Excitatory Synapse Regulation Of AMPA Glutamate Receptor Clustering
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