TMEM126B and TENM4

		TMEM126B	TENM4
Description		transmembrane protein 126B	teneurin transmembrane protein 4
Image		No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Membrane	Nucleus Cytoplasm Plasma Membrane Membrane Cell Projection Neuron Projection Glutamatergic Synapse
	Molecular Function	Protein Binding	Protein Binding Identical Protein Binding Protein Homodimerization Activity Protein Heterodimerization Activity Cell Adhesion Molecule Binding
	Biological Process	Mitochondrion Organization Response To Food Mitochondrial Respiratory Chain Complex I Assembly	Gastrulation With Mouth Forming Second Signal Transduction Cell Differentiation Regulation Of Myelination Positive Regulation Of Myelination Central Nervous System Myelin Formation Neuron Development Positive Regulation Of Oligodendrocyte Differentiation Cardiac Muscle Cell Proliferation Cardiac Cell Fate Specification Synaptic Membrane Adhesion Positive Regulation Of Gastrulation
Pathways		Complex I biogenesis
Drugs
Diseases
GWAS		Height ( 19570815) Metabolite levels ( 23823483)	Attention deficit hyperactivity disorder (inattention symptoms) ( 32595297) Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Gut microbiota alpha diversity (PD_whole_tree index) ( 33208821) Hair greying ( 26926045) Lactate dehydrogenase levels ( 29403010) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lung cancer in never smokers ( 28604730) Night sleep phenotypes ( 27126917) Right lateral prefrontal cortical growth ( 29682794) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) Tourette syndrome ( 30818990)
Interacting Genes		6 interacting genes: ALG8 APP MRFAP1L1 NARS2 TENM4 UBC	11 interacting genes: DOCK2 GAB2 HOXB9 LCE3D LGALS4 PLSCR4 RSF1 SHFL TMEM126B ZNF587 ZNF696
Entrez ID		55863	26011
HPRD ID		13715	19400
Ensembl ID		ENSG00000171204	ENSG00000149256
Uniprot IDs		Q8IUX1	Q6N022
PDB IDs			7BAM 7BAN 7BAO 7PLP
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Regulation Of Nervous System Process Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cardiac Cell Fate Specification Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Dolichyl Pyrophosphate Glc1Man9GlcNAc2 Alpha-1,3-glucosyltransferase Activity Asparagine-tRNA Ligase Activity Asparaginyl-tRNA Aminoacylation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Cellular Response To Norepinephrine Stimulus Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Main Axon Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Central Nervous System Myelin Formation Axon Choice Point Recognition Positive Regulation Of Gastrulation Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion
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