LRIF1 and BRD7

Number of citations of the paper that reports this interaction (PubMedID 15383276)
0

Data Source:
BioGRID (two hybrid)

		LRIF1	BRD7
Description		ligand dependent nuclear receptor interacting factor 1	bromodomain containing 7
Image		No pdb structure
GO Annotations	Cellular Component	Chromosome, Telomeric Region Barr Body Nucleus Nucleoplasm Chromosome Nuclear Matrix Centriolar Satellite	Kinetochore Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Nuclear Matrix RSC-type Complex
	Molecular Function	Protein Binding Nuclear Retinoic Acid Receptor Binding	Transcription Cis-regulatory Region Binding P53 Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Histone Binding Histone H3K14ac Reader Activity Histone Reader Activity
	Biological Process	Regulation Of DNA-templated Transcription Dosage Compensation By Inactivation Of X Chromosome	Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Regulation Of Mitotic Cell Cycle Wnt Signaling Pathway Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of T Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Transcription Initiation-coupled Chromatin Remodeling Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Regulation Of G0 To G1 Transition Regulation Of G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways			Regulation of TP53 Activity through Acetylation Formation of the polybromo-BAF (pBAF) complex
Drugs
Diseases
GWAS		Bone mineral content ( 31790847) Intraocular pressure ( 30591961)	Allergic sensitization ( 30013184) Epilepsy ( 30531953) Liver enzyme levels (alanine transaminase) ( 24124411) Medication use (thyroid preparations) ( 31015401)
Interacting Genes		144 interacting genes: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BANP BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 CLCC1 COX17 CPE CRACR2A CRADD CRCP CRCT1 CRIPTO DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FHL2 FOSL2 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 H3-4 HAP1 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NOC2L NR3C1 NRBP1 NTAQ1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR1C POLR2C POLR3F PPARG PQBP1 PRKAB2 PRKAR2A PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SNU13 SPATA18 SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSEN15 TSPAN6 UBE2V2 UNC119 VIM VPS26C WDR62 WWC1 ZNF24 ZNF410	30 interacting genes: AGR2 BARD1 BHLHE40 BRD3 BTBD2 DVL1 FTH1 H2AC16 H2BC21 H3-3A H3-4 H3C14 H4C16 HAP1 HNRNPUL1 IRF2 LAMA4 LRIF1 MX1 NEFL PAFAH1B3 PARP1 PCBD1 PLEKHF2 PSMD11 PTPN13 RIF1 RPLP1 SERPINB9 TRIM24
Entrez ID		55791	29117
HPRD ID		17975	12531
Ensembl ID		ENSG00000121931	ENSG00000166164
Uniprot IDs		Q5T3J3	A0AA34QVS2 Q9NPI1
PDB IDs			2I7K 5MQ1 6PPA 6V0Q 6V16 6V17 6V1E 6V1F 6V1H 7VDV 7Y8R
Enriched GO Terms of Interacting Partners?		Nucleus Nucleoplasm Protein Binding Cytoplasm Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Programmed Cell Death Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Apoptotic Process Chromatin Binding Positive Regulation Of Programmed Cell Death Regulation Of Macromolecule Metabolic Process Negative Regulation Of RNA Metabolic Process Nuclear Receptor Activity Regulation Of Intracellular Signal Transduction Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Population Proliferation Regulation Of Primary Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Cytosol Positive Regulation Of Apoptotic Process Nucleolus Negative Regulation Of Transcription By RNA Polymerase II Biological_process Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Development Negative Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Hemopoiesis Chromatin Organization Regulation Of Cell Differentiation Mononuclear Cell Differentiation Regulation Of Lymphocyte Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Signal Transduction Positive Regulation Of Fibroblast Proliferation DNA-directed RNA Polymerase Activity Positive Regulation Of Biosynthetic Process Chromatin Remodeling Regulation Of Cell Cycle Process Regulation Of DNA Repair Regulation Of Cell Cycle G1/S Phase Transition	Chromatin Remodeling Chromatin Organization Protein Heterodimerization Activity Structural Constituent Of Chromatin Nucleosome Chromosome Chromosome, Telomeric Region Nucleosome Assembly Nucleosome Organization Protein-DNA Complex Assembly Nucleus Barr Body Telomere Organization Negative Regulation Of Metabolic Process Protein Localization To Chromatin Heterochromatin Formation Subtelomeric Heterochromatin Formation Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Nucleoplasm Chromatin Cellular Response To Estrogen Stimulus Extracellular Exosome Retrograde Axonal Transport Protein Binding Protein Localization To Chromosome NAD+-histone H3S10 Serine ADP-ribosyltransferase Activity NAD+-histone H2BS6 Serine ADP-ribosyltransferase Activity NAD+-histone H2BE35 Glutamate ADP-ribosyltransferase Activity NAD+-protein-histidine ADP-ribosyltransferase Activity NAD+-protein-tyrosine ADP-ribosyltransferase Activity Negative Regulation Of MRNA 3'-end Processing Epigenetic Regulation Of Gene Expression Histone H3K9cr Reader Activity Histone H3K27cr Reader Activity Histone H3K18cr Reader Activity Histone H3K23ac Reader Activity Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Neurotrophin Production Positive Regulation Of ERBB Signaling Pathway Chromosome, Telomeric Repeat Region Regulation Of Developmental Process Growth Cone Response To Mineralocorticoid
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