PRKAR2B and CFAP91

Number of citations of the paper that reports this interaction (PubMedID 12223483)
0

Data Source:
BioGRID (pull down)

		PRKAR2B	CFAP91
Description		protein kinase cAMP-dependent type II regulatory subunit beta	cilia and flagella associated protein 91
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Centrosome Cytosol Plasma Membrane CAMP-dependent Protein Kinase Complex Membrane Dendrite Neuronal Cell Body Dendritic Spine Dendritic Shaft Perinuclear Region Of Cytoplasm Extracellular Exosome Ciliary Base Postsynapse Glutamatergic Synapse	Radial Spoke Stalk Cytoplasm Mitochondrion Cytoskeleton Axoneme Motile Cilium Cell Projection
	Molecular Function	Nucleotide Binding CAMP-dependent Protein Kinase Inhibitor Activity Protein Binding CAMP-dependent Protein Kinase Regulator Activity Protein Kinase Binding Protein Domain Specific Binding CAMP Binding Ubiquitin Protein Ligase Binding Protein Kinase A Catalytic Subunit Binding	Protein Binding
	Biological Process	Fatty Acid Metabolic Process Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Learning Intracellular Signal Transduction Modulation Of Chemical Synaptic Transmission Response To Antipsychotic Drug Negative Regulation Of CAMP/PKA Signal Transduction	Cilium Movement Spermatogenesis Cell Differentiation Axonemal Central Apparatus Assembly
Pathways		PKA activation PKA activation in glucagon signalling DARPP-32 events Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Glucagon-like Peptide-1 (GLP1) regulates insulin secretion Vasopressin regulates renal water homeostasis via Aquaporins CREB1 phosphorylation through the activation of Adenylate Cyclase Hedgehog 'off' state Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2 GPER1 signaling ADORA2B mediated anti-inflammatory cytokines production FCGR3A-mediated IL10 synthesis Factors involved in megakaryocyte development and platelet production High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells
Drugs		Cyclic adenosine monophosphate
Diseases
GWAS		Adverse response to lamotrigine and phenytoin ( 22379998) Bladder cancer (smoking interaction) ( 24662972) Blood urea nitrogen levels ( 31152163) Femur bone mineral density x serum urate levels interaction ( 34046847) Height ( 28552196) Manganese levels ( 26025379) Response to antipsychotic treatment ( 20195266) Triglyceride levels ( 32203549)
Interacting Genes		25 interacting genes: ABCB4 AKAP1 AKAP10 AKAP11 AKAP14 AKAP19 AKAP4 AKAP5 AKAP9 CBR1 CFAP91 ECM1 GNAI3 KIF5B LAMB1 LASP1 LRCH4 MT1H NBEA OGT PAK1IP1 RAP2B RPL30 TAF12 TFR2	6 interacting genes: AKAP1 CD200 DPY30 DSCAM MYCBP PRKAR2B
Entrez ID		5577	89876
HPRD ID		01486	10782
Ensembl ID		ENSG00000005249	ENSG00000183833
Uniprot IDs		B3KY43 P31323	Q7Z4T9
PDB IDs			8J07
Enriched GO Terms of Interacting Partners?		Protein Kinase A Regulatory Subunit Binding Protein Kinase A Binding Negative Regulation Of Adenylate Cyclase Activity CAMP-dependent Protein Kinase Complex	Cell-cell Adhesion Mediator Activity Neuronal Cell Body Post-embryonic Retina Morphogenesis In Camera-type Eye Netrin Receptor Binding Response To Antipsychotic Drug
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