CNDP2 and CD226

		CNDP2	CD226
Description		carnosine dipeptidase 2	CD226 molecule
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Extracellular Exosome	Plasma Membrane External Side Of Plasma Membrane Cell Surface Membrane Membrane Raft
	Molecular Function	Carboxypeptidase Activity Protein Binding Peptidase Activity Metallopeptidase Activity Hydrolase Activity Dipeptidase Activity Metal Ion Binding Metallodipeptidase Activity	Integrin Binding Protein Binding Protein Kinase Binding Signaling Receptor Activity Identical Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Proteolysis	Positive Regulation Of Natural Killer Cell Cytokine Production Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Immunoglobulin Mediated Immune Response Cell Adhesion Signal Transduction Cell Recognition Positive Regulation Of Type II Interferon Production Positive Regulation Of Mast Cell Activation Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of T Cell Receptor Signaling Pathway Positive Regulation Of Fc Receptor Mediated Stimulatory Signaling Pathway
Pathways		Glutathione synthesis and recycling Paracetamol ADME	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
Drugs
Diseases			Type I diabetes mellitus
GWAS		Refractive error ( 23396134 32231278) Serum metabolite levels ( 33031748)	Autoimmune thyroid disease ( 32581359) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Chronic widespread musculoskeletal pain ( 33331911) Eosinophil count ( 32888494) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 27863252 32888494) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean platelet volume ( 32888494 31194788 27863252 22139419 19820697) Mean spheric corpuscular volume ( 32888494) Medication use (thyroid preparations) ( 31015401) Multiple sclerosis ( 31604244) Neutrophil count ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494 27863252) Plateletcrit ( 32888494 27863252) Primary sclerosing cholangitis ( 27992413 23603763) Reticulocyte fraction of red cells ( 32888494) Rheumatoid arthritis ( 24390342 30423114) Systemic lupus erythematosus ( 33272962) Type 1 diabetes ( 21829393 17554260 25751624) White blood cell count ( 32888494)
Interacting Genes		9 interacting genes: CD226 CNDP1 CRK DAPP1 FILNC1 NDRG1 OGT STAT3 ZDHHC17	8 interacting genes: CNDP2 DOK6 FYN GALR1 ITGB2 NECTIN2 PVR TSHZ1
Entrez ID		55748	10666
HPRD ID		09893	09252
Ensembl ID		ENSG00000133313	ENSG00000150637
Uniprot IDs		Q96KP4	J3QR77 Q15762
PDB IDs		4RUH	6ISB 6O3O
Enriched GO Terms of Interacting Partners?		Regulation Of Natural Killer Cell Mediated Immunity Helper T Cell Diapedesis Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Signaling Receptor Binding Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Response To Peptide Hormone Signaling Adaptor Activity Protein Phosphorylated Amino Acid Binding Regulation Of Rac Protein Signal Transduction Positive Regulation Of Signaling Regulation Of Natural Killer Cell Mediated Cytotoxicity Response To Cholecystokinin Regulation Of ATP Metabolic Process Regulation Of Carbohydrate Catabolic Process Chromatin DNA Binding Regulation Of Glycolytic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Phosphatidylinositol-3,4,5-trisphosphate Binding Postsynaptic Golgi Apparatus Regulation Of Modification Of Synapse Structure, Modulating Synaptic Transmission Perforant Pathway To Dendrate Granule Cell Synapse Regulation Of Leukocyte Mediated Cytotoxicity Cerebellar Neuron Development Negative Regulation Of Primary MiRNA Processing Negative Regulation Of Hydrogen Peroxide Biosynthetic Process Positive Regulation Of Skeletal Muscle Cell Proliferation Protein O-acetylglucosaminyltransferase Activity Positive Regulation Of Intracellular Signal Transduction Plasma Membrane RNA Sequestering Activity Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Response To Wounding Diapedesis Regulation Of Protein Localization To Membrane Response To Hormone Negative Regulation Of Hydrogen Peroxide Metabolic Process Postsynapse To Nucleus Signaling Pathway Interleukin-11-mediated Signaling Pathway Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Interleukin-23-mediated Signaling Pathway T-helper 17 Type Immune Response Glutamatergic Synapse Positive Regulation Of Transcription From RNA Polymerase II Promoter By Glucose Non-canonical Inflammasome Complex Assembly Positive Regulation Of Transcription By Glucose	Susceptibility To T Cell Mediated Cytotoxicity Susceptibility To Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Directed Against Tumor Cell Target Positive Regulation Of Natural Killer Cell Mediated Immune Response To Tumor Cell Cell Adhesion Molecule Binding Positive Regulation Of Immune Response To Tumor Cell Positive Regulation Of Protein Targeting To Membrane Negative Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Protein Targeting To Membrane Negative Regulation Of Immune Response Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Response To Tumor Cell Positive Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Immune Response Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Regulation Of T Cell Mediated Cytotoxicity Positive Regulation Of Immune Effector Process Negative Regulation Of Defense Response Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Innate Immune Response Regulation Of Natural Killer Cell Mediated Immunity Cellular Response To Glycine Response To Singlet Oxygen Positive Regulation Of T Cell Mediated Immunity Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Coreceptor-mediated Virion Attachment To Host Cell Cellular Anatomical Entity Morphogenesis Regulation Of Immune Response Leukocyte Mediated Cytotoxicity Immune Effector Process Virus Receptor Activity Positive Regulation Of Immune System Process Focal Adhesion Response To Glycine Regulation Of Innate Immune Response Integrin AlphaM-beta2 Complex Integrin AlphaX-beta2 Complex Integrin AlphaL-beta2 Complex Negative Regulation Of Innate Immune Response Regulation Of Leukocyte Mediated Cytotoxicity Sperm Mitochondrion Organization Positive Regulation Of Defense Response Regulation Of T Cell Mediated Immunity Cell-cell Adhesion Negative Regulation Of Hydrogen Peroxide Biosynthetic Process ICAM-3 Receptor Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?