PIGV and ZNF593

		PIGV	ZNF593
Description		phosphatidylinositol glycan anchor biosynthesis class V	zinc finger protein 593
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Mannosyltransferase Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	Alpha-1,6-mannosyltransferase Activity Mannosyltransferase Activity GPI Mannosyltransferase Activity Protein Binding Transferase Activity Glycosyltransferase Activity	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Ribonucleoprotein Complex Binding Metal Ion Binding Preribosome Binding
	Biological Process	GPI Anchor Biosynthetic Process	Ribosome Biogenesis Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Pathways		Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Blond vs. brown/black hair color ( 30531825) Blood protein levels in cardiovascular risk ( 28369058) Chronic obstructive pulmonary disease or high blood pressure (pleiotropy) ( 30940143) HDL cholesterol ( 24097068 25961943) HDL cholesterol levels ( 28334899) LDL cholesterol ( 24097068 25961943) LDL cholesterol levels ( 28334899) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 27863252) Sum basophil neutrophil counts ( 27863252) Triglyceride levels ( 28334899 32154731) Triglycerides ( 24097068)
Interacting Genes		5 interacting genes: MAD2L2 MADCAM1 MTFR1L PITHD1 ZNF593	11 interacting genes: DDIT4L GPR3 LNX1 MAP3K20 MAP3K7 MAPK8IP2 PICK1 PIGV POLR1H RAB1A SRPK2
Entrez ID		55650	51042
HPRD ID		07912	15866
Ensembl ID		ENSG00000060642	ENSG00000142684
Uniprot IDs		A0A6I8PU65 A0A8I5KQ29 A0A8I5KRV8 Q9NUD9	O00488
PDB IDs			1ZR9 6LSS 6LU8 8FL2 8FL3 8FL4 8FL6 8FL7 8FL9 8FLA 8FLB 8FLC 8FLD 8FLE 8FLF 8IDT 8IDY 8IE3 8INE 8INF 8INK 8IPD 8IPX 8IPY 8IR3 8RL2
Enriched GO Terms of Interacting Partners?		DNA Damage Response, Signal Transduction Resulting In Transcription Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Penetration Of Cumulus Oophorus	JNK Cascade Phosphorylation Protein Phosphorylation P38MAPK Cascade Stress-activated MAPK Cascade MAP Kinase Kinase Kinase Activity Stress-activated Protein Kinase Signaling Cascade Magnesium Ion Binding Regulation Of Stress-activated Protein Kinase Signaling Cascade Protein Kinase Activator Activity MAPK Cascade Positive Regulation Of Mitotic DNA Damage Checkpoint Mannosyltransferase Complex Defense Response Phosphate-containing Compound Metabolic Process Positive Regulation Of Cell Cycle Protein Serine Kinase Activity Alpha-1,6-mannosyltransferase Activity Intracellular Signaling Cassette Protein Serine/threonine Kinase Activity Negative Regulation Of Signaling I-kappaB Phosphorylation Linear Polyubiquitin Binding Negative Regulation Of Cell Communication Termination Of RNA Polymerase I Transcription Negative Regulation Of Translation In Response To Endoplasmic Reticulum Stress GPI Mannosyltransferase Activity
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?