ZCCHC8 and SBNO1

		ZCCHC8	SBNO1
Description		zinc finger CCHC-type containing 8	strawberry notch homolog 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Nuclear Body TRAMP Complex Catalytic Step 2 Spliceosome	Nucleus
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Chromatin DNA Binding Histone Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing SnRNA Catabolic Process MRNA 3'-end Processing Co-transcriptional LncRNA 3' End Processing, Cleavage And Polyadenylation Pathway	Regulation Of DNA-templated Transcription Inflammatory Response Positive Regulation Of Signal Transduction Wnt Signaling Pathway Negative Regulation Of Canonical NF-kappaB Signal Transduction Negative Regulation Of MAPK Cascade Positive Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Neuroinflammatory Response Positive Regulation Of Neural Precursor Cell Proliferation
Pathways		Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Nuclear RNA decay
Drugs
Diseases
GWAS		A body shape index ( 34021172) Chronotype ( 30696823) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	A body shape index ( 34021172) Allergy ( 27182965) Autism spectrum disorder or schizophrenia ( 28540026) Brain morphology (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878 27618447) Educational attainment ( 25201988) HDL cholesterol ( 20686565 30275531 24097068) HDL cholesterol levels ( 28334899 30698716) HDL cholesterol levels in current drinkers ( 30698716) HDL cholesterol levels x alcohol consumption (drinkers vs non-drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x alcohol consumption (regular vs non-regular drinkers) interaction (2df) ( 30698716) HDL cholesterol levels x long total sleep time interaction (2df test) ( 31719535) Head circumference (infant) ( 22504419) Height ( 20881960 25282103) Hip circumference adjusted for BMI ( 34021172) Hip index ( 34021172) Knee osteoarthritis ( 30374069) Liver enzyme levels (gamma-glutamyl transferase) ( 33972514) Lymphocyte count ( 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 27863252) Plateletcrit ( 32888494) Schizophrenia ( 29483656 25056061 23974872) Tourette syndrome ( 30818990) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		4 interacting genes: APP FILNC1 PRPF40A RBM11	2 interacting genes: DSCR9 GSK3A
Entrez ID		55596	55206
HPRD ID		11698	11533
Ensembl ID		ENSG00000033030	ENSG00000139697
Uniprot IDs		Q6NZY4	A3KN83
PDB IDs		5LXR 5LXY 6C90 7S7B 7S7C 7Z4Y 7Z4Z 7Z52
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Wnt Signaling Pathway Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle	Negative Regulation Of UDP-glucose Catabolic Process Negative Regulation Of Type B Pancreatic Cell Development Extrinsic Apoptotic Signaling Pathway Regulation Of Mitochondrion Organization Negative Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Adenylate Cyclase-activating Adrenergic Receptor Signaling Pathway Mitochondrial Intermembrane Space LncRNA Processing Co-transcriptional LncRNA 3' End Processing, Cleavage And Polyadenylation Pathway
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