ZCCHC8

Description		zinc finger CCHC-type containing 8
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Nuclear Body TRAMP Complex Catalytic Step 2 Spliceosome
	Molecular Function	Nucleic Acid Binding RNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	MRNA Splicing, Via Spliceosome RNA Processing MRNA Processing RNA Splicing SnRNA Catabolic Process MRNA 3'-end Processing Co-transcriptional LncRNA 3' End Processing, Cleavage And Polyadenylation Pathway
Pathways		Regulation of endogenous retroelements by the Human Silencing Hub (HUSH) complex Nuclear RNA decay
Drugs
Diseases
GWAS		A body shape index ( 34021172) Chronotype ( 30696823) Hip circumference adjusted for BMI ( 34021172) Waist circumference adjusted for body mass index ( 34021172) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Novel Interacting Genes		5 novel interacting genes: APP FILNC1 PRPF40A RBM11 SBNO1
Interacting Genes		5 interacting genes: APP FILNC1 PRPF40A RBM11 SBNO1
Entrez ID		55596
HPRD ID		11698
Ensembl ID		ENSG00000033030
Uniprot IDs		Q6NZY4
PDB IDs		5LXR 5LXY 6C90 7S7B 7S7C 7Z4Y 7Z4Z 7Z52
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Low-density Lipoprotein Particle Mediated Signaling Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Regulation Of Canonical Wnt Signaling Pathway Axon Choice Point Recognition Heparan Sulfate Binding Signaling Receptor Activator Activity Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Wnt Signaling Pathway Negative Regulation Of Blood Circulation Regulation Of Superoxide Anion Generation Collateral Sprouting Heparan Sulfate Proteoglycan Binding Acetylcholine Receptor Binding Golgi-associated Vesicle Insulin Receptor Binding Apolipoprotein Binding Response To Lead Ion Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel High-density Lipoprotein Particle Very-low-density Lipoprotein Particle
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