CNOT11 and FAM193B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CNOT11	FAM193B
Description		CCR4-NOT transcription complex subunit 11	family with sequence similarity 193 member B
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol CCR4-NOT Complex	Nucleus Nucleoplasm Nucleolus Cytoplasm Nuclear Speck
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Poly(A) Tail Shortening Regulation Of Translation Regulatory NcRNA-mediated Gene Silencing
Pathways		Deadenylation of mRNA TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain M-decay: degradation of maternal mRNAs by maternally stored factors
Drugs
Diseases
GWAS		Carotid intima media thickness x smoking interaction ( 32117412)	Appendicular lean mass ( 33097823) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: CATSPERT FAM193B MEOX1 OBI1 OGT	12 interacting genes: ATXN1 CDC25A CNOT11 GOLGA2 GSK3A GSK3B LDOC1 MAPK8 PKN2 SPANXN2 TRIM23 TRIM27
Entrez ID		55571	54540
HPRD ID		12812	07671
Ensembl ID		ENSG00000158435	ENSG00000146067
Uniprot IDs		Q9UKZ1	Q96PV7
PDB IDs		8BFH 8BFI 8BFJ 8FY3
Enriched GO Terms of Interacting Partners?			Regulation Of Autophagy Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen (starch) Synthase Activity Regulation Of Protein Binding Regulation Of Glycogen (starch) Synthase Activity Positive Regulation Of Autophagy Beta-arrestin-dependent Dopamine Receptor Signaling Pathway Cellular Response To Interleukin-3 Excitatory Postsynaptic Potential Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Glycogen Biosynthetic Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Catabolic Process Beta-catenin Destruction Complex Regulation Of Postsynaptic Membrane Potential Protein Kinase A Catalytic Subunit Binding Protein Serine Kinase Activity Tau-protein Kinase Activity Negative Regulation Of Catabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Protein Serine/threonine Kinase Activity Viral Protein Processing Positive Regulation Of Mitochondrial Membrane Permeability Negative Regulation Of Protein Binding Regulation Of Glycogen Biosynthetic Process Cellular Response To Lipid Positive Regulation Of Membrane Permeability Regulation Of Protein Metabolic Process Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Protein Kinase Activity Positive Regulation Of Establishment Of Protein Localization To Mitochondrion Regulation Of Glycogen Metabolic Process Protein Modification Process Tau Protein Binding Peptidyl-serine Phosphorylation Regulation Of Catalytic Activity Postsynapse Transferase Activity Positive Regulation Of Metabolic Process Negative Regulation Of UDP-glucose Catabolic Process Kinase Activity Regulation Of Mitochondrial Membrane Permeability Regulation Of Microtubule Anchoring At Centrosome JUN Phosphorylation Regulation Of Protein Modification Process Glycogen Metabolic Process Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Membrane Permeability Positive Regulation Of Neuron Apoptotic Process
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