GPRC5D and FXYD6-FXYD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		GPRC5D	FXYD6-FXYD2
Description		G protein-coupled receptor class C group 5 member D	FXYD6-FXYD2 readthrough
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane Intracellular Membrane-bounded Organelle Receptor Complex Extracellular Exosome
	Molecular Function	G Protein-coupled Receptor Activity Protein Binding Protein Kinase Activator Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway
Pathways
Drugs
Diseases
GWAS			Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		31 interacting genes: APOL3 BTN2A2 C14orf180 C1GALT1 CCL4 EMP1 ERC1 ERMP1 FXYD3 FXYD6-FXYD2 GYPA IFITM3 IGFBP5 LHFPL5 LRRC25 MS4A6A OSMR PMP22 PRRT2 PVR SLC30A2 SLC66A1 SYNDIG1 TMEM120B TMEM19 TMEM208 TMEM79 TRARG1 TWSG1 UNC93B1 YIPF1	34 interacting genes: APH1B APOL3 AQP6 AVPR2 BEST1 BNIP3 CERS4 CLDN5 ERGIC3 FAM210B GPR152 GPR37L1 GPRC5D MTIF3 PGRMC2 RNF170 SLC10A1 SLC10A6 SLC16A13 SLC19A3 SLC2A13 SLC34A2 SLC35H1 SLC7A8 SPCS1 TLCD4 TMEM14B TMEM167B TMEM205 TMEM41A TMPPE TMX2 TRHR UNC93A
Entrez ID		55507	100533181
HPRD ID		07604
Ensembl ID		ENSG00000111291	ENSG00000255245
Uniprot IDs		Q9NZD1	A0A087WZ82 A0A0A6YYL5
PDB IDs		8YZK 9IMA
Enriched GO Terms of Interacting Partners?		Membrane	Membrane Transmembrane Transport Bile Acid:sodium Symporter Activity Symporter Activity Organic Anion Transport Renal Water Transport Carboxylic Acid Transport Organic Acid Transport Protein Binding Organic Hydroxy Compound Transport Endoplasmic Reticulum G Protein-coupled Receptor Activity Bile Acid And Bile Salt Transport
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