NPY4R and PPY

Number of citations of the paper that reports this interaction (PubMedID 7493937)
0

Data Source:
HPRD (in vitro)

		NPY4R	PPY
Description		neuropeptide Y receptor Y4	pancreatic polypeptide
Image
GO Annotations	Cellular Component	Plasma Membrane Membrane Neuron Projection	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Pancreatic Polypeptide Receptor Activity G Protein-coupled Receptor Activity Neuropeptide Y Receptor Activity Peptide Hormone Binding Neuropeptide Binding	G Protein-coupled Receptor Binding Hormone Activity Neuropeptide Hormone Activity Protein Binding Neuropeptide Y Receptor Binding
	Biological Process	Cell Communication Signal Transduction G Protein-coupled Receptor Signaling Pathway Neuropeptide Signaling Pathway Signaling	Neuropeptide Signaling Pathway Feeding Behavior Protein Secretion
Pathways		Peptide ligand-binding receptors G alpha (i) signalling events	Peptide ligand-binding receptors G alpha (i) signalling events
Drugs		Peptide YY (3-36) Obinepitide TM30339
Diseases
GWAS
Interacting Genes		3 interacting genes: NPY PPY PYY	2 interacting genes: CYSRT1 NPY4R
Entrez ID		5540	5539
HPRD ID		03476	01340
Ensembl ID		ENSG00000204174	ENSG00000108849
Uniprot IDs		P50391	P01298
PDB IDs		7X9C	1TZ4 1TZ5 7X9C
Enriched GO Terms of Interacting Partners?		Neuropeptide Y Receptor Binding Neuropeptide Hormone Activity G Protein-coupled Receptor Binding Feeding Behavior Neuropeptide Signaling Pathway Hormone Activity Intestinal Epithelial Cell Differentiation G Protein-coupled Receptor Signaling Pathway Short-day Photoperiodism Regulation Of Nerve Growth Factor Production Positive Regulation Of Eating Behavior Positive Regulation Of Response To Food Positive Regulation Of Appetite Extracellular Space Negative Regulation Of Acute Inflammatory Response To Antigenic Stimulus Positive Regulation Of Dopamine Metabolic Process Regulation Of Eating Behavior Monocyte Activation Extracellular Region Antifungal Humoral Response Synaptic Signaling Via Neuropeptide Adult Feeding Behavior Epithelial Cell Differentiation Positive Regulation Of Feeding Behavior Negative Regulation Of Acute Inflammatory Response Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Response To Yeast Regulation Of Acute Inflammatory Response To Antigenic Stimulus Regulation Of Response To Food Regulation Of Dopamine Metabolic Process Neuronal Dense Core Vesicle Regulation Of Appetite Regulation Of Feeding Behavior Photoperiodism Positive Regulation Of Behavior Negative Regulation Of Inflammatory Response To Antigenic Stimulus Regulation Of Response To Nutrient Levels Terminal Bouton Positive Regulation Of Nitric Oxide Metabolic Process Calcium Channel Regulator Activity Central Nervous System Neuron Development Negative Regulation Of Blood Pressure Regulation Of Acute Inflammatory Response Regulation Of Synaptic Vesicle Exocytosis Defense Response To Fungus G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Regulation Of Cytosolic Calcium Ion Concentration Response To Fungus Antibacterial Humoral Response Neuron Cellular Homeostasis	Pancreatic Polypeptide Receptor Activity Neuropeptide Y Receptor Activity Peptide Hormone Binding Neuropeptide Binding Biological Process Involved In Interaction With Symbiont Skin Epidermis Development Establishment Of Skin Barrier Cornified Envelope Neuropeptide Signaling Pathway
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