CHDH and SEZ6

Number of citations of the paper that reports this interaction (PubMedID 21900206)
0

Data Source:
BioGRID (two hybrid)

		CHDH	SEZ6
Description		choline dehydrogenase	seizure related 6 homolog
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane	Endoplasmic Reticulum Plasma Membrane Membrane Neuronal Cell Body Dendritic Spine Dendritic Shaft Perinuclear Region Of Cytoplasm Apical Dendrite
	Molecular Function	Protein Binding Choline Dehydrogenase Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On CH-OH Group Of Donors Flavin Adenine Dinucleotide Binding	Protein Binding
	Biological Process	Glycine Betaine Biosynthetic Process From Choline Choline Catabolic Process	Adult Locomotory Behavior Cerebellar Purkinje Cell Layer Development Regulation Of Dendrite Development Synapse Maturation Excitatory Postsynaptic Potential
Pathways		Choline catabolism
Drugs
Diseases
GWAS		Axial length ( 24144296) Body mass index ( 26426971) interleukin 17 receptor B levels ( 25147954) Medication use (calcium channel blockers) ( 31015401) Refractive error ( 32231278) Smoking status (ever vs never smokers) ( 30643258)	Language functional connectivity ( 34929384) Mean arterial pressure ( 27618448)
Interacting Genes		3 interacting genes: NOTCH2NLA RPL8 SEZ6	3 interacting genes: CHDH TNK2 UBQLN2
Entrez ID		55349	124925
HPRD ID		13050	18041
Ensembl ID		ENSG00000016391	ENSG00000063015
Uniprot IDs		Q8NE62	Q53EL9
PDB IDs
Enriched GO Terms of Interacting Partners?			Regulation Of Clathrin-dependent Endocytosis Regulation Of Receptor-mediated Endocytosis Grb2-EGFR Complex Negative Regulation Of G Protein-coupled Receptor Internalization Glycine Betaine Biosynthetic Process From Choline Choline Dehydrogenase Activity Cytoophidium Negative Regulation Of Clathrin-dependent Endocytosis Oxidoreductase Activity, Acting On CH-OH Group Of Donors Choline Catabolic Process Regulation Of Endocytosis Choline Metabolic Process GTPase Inhibitor Activity Regulation Of Vesicle-mediated Transport Positive Regulation Of ERAD Pathway Negative Regulation Of Receptor Internalization Amino-acid Betaine Metabolic Process WW Domain Binding Regulation Of ERAD Pathway Protein Serine/threonine/tyrosine Kinase Activity Negative Regulation Of Receptor-mediated Endocytosis Epidermal Growth Factor Receptor Binding Positive Regulation Of Protein Metabolic Process Cytoplasmic Vesicle Polyubiquitin Modification-dependent Protein Binding Positive Regulation Of Response To Endoplasmic Reticulum Stress Non-membrane Spanning Protein Tyrosine Kinase Activity Regulation Of Autophagosome Assembly Molecular Condensate Scaffold Activity Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Vacuole Organization Flavin Adenine Dinucleotide Binding
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