CCDC91 and GGA1

Number of citations of the paper that reports this interaction (PubMedID 12808037)
46

Data Source:
HPRD (in vitro, in vivo)

		CCDC91	GGA1
Description		coiled-coil domain containing 91	golgi associated, gamma adaptin ear containing, ARF binding protein 1
Image
GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Trans-Golgi Network Cytosol Membrane	Nucleoplasm Endosome Early Endosome Golgi Apparatus Trans-Golgi Network Cytosol Endosome Membrane Membrane Early Endosome Membrane Protein-containing Complex
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Small GTPase Binding Phosphatidylinositol Binding Ubiquitin Binding
	Biological Process	Protein Transport Golgi Vesicle Transport Golgi To Lysosome Transport	Intracellular Protein Transport Golgi To Plasma Membrane Transport Intracellular Protein Localization Protein Transport Vesicle-mediated Transport Protein Catabolic Process Protein Localization To Cell Surface Retrograde Transport, Endosome To Golgi Golgi To Plasma Membrane Protein Transport Positive Regulation Of Protein Catabolic Process Protein Localization To Ciliary Membrane
Pathways			TBC/RABGAPs Amyloid fiber formation
Drugs
Diseases
GWAS		Adverse response to drug ( 30420678) Appendicular lean mass ( 33097823) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Bone ultrasound measurement (velocity of sound) ( 28472463) Brain morphology (MOSTest) ( 32665545) Breast size ( 27182965) Chronic obstructive pulmonary disease ( 30804561 33909500) FEV1 ( 30804560) Finger osteoarthritis severity (hand Klsum) ( 33055079) Glaucoma (primary open-angle) ( 33627673) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hand osteoarthritis severity (hand Klsum) ( 33055079) Heel bone mineral density ( 30598549) Height ( 25282103 23563607 31562340 20881960 28552196) High light scatter reticulocyte count ( 32888494) Hip circumference adjusted for BMI ( 34021172 25673412) Immature fraction of reticulocytes ( 32888494) Lumbar spine bone mineral density (trabecular) ( 27476799) Lung function (FEV1) ( 26635082 28166213) Lung function (FVC) ( 26635082 28166213 30804560) Lung function (low FEV1 vs high FEV1) ( 26423011) Lung function in never smokers (low FEV1 vs high FEV1) ( 26423011) Narrowest width of the femoral neck ( 30888730) Obesity-related traits ( 23251661) Ossification of the posterior longitudinal ligament of the spine ( 25064007) Osteoarthritis of the hand ( 28855172) Peak expiratory flow ( 30804560) Reticulocyte fraction of red cells ( 32888494) Waist circumference adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for BMI in non-smokers ( 28443625) Waist circumference adjusted for body mass index ( 28448500 25673412 34021172)	Health literacy ( 31250787)
Interacting Genes		12 interacting genes: AP1G1 CDC37 DAPK2 ECT2 EWSR1 GGA1 GGA2 LNX1 PRR5L SYNRG TESC TMTC1	49 interacting genes: ADRA2B AFTPH AP1AR AP1G1 APP ARF1 ARF3 ARF5 ATXN7L1 BACE1 BACE2 C1orf216 CCDC91 CDKL3 CDKN2A CFTR CLINT1 CLTC CSNK2A1 DGCR6L DTNB EGFR ETS1 F8 GGA2 GGA3 GTPBP4 GTSE1 IGF2R ING5 JUN LRP3 M6PR NPM1 RABEP1 RABGEF1 RNF11 RPS27A SCARB1 SMAD3 SORL1 SORT1 STAB1 SYNRG TOLLIP TP53 TSG101 UBC VPS18
Entrez ID		55297	26088
HPRD ID		16905	12078
Ensembl ID		ENSG00000123106	ENSG00000100083
Uniprot IDs		Q05D28 Q7Z6B0	Q9UJY5
PDB IDs		1OM9	1J2J 1JWF 1JWG 1NA8 1NAF 1NWM 1O3X 1OM9 1OXZ 1PY1 1UJJ 1UJK 1X79 2DWX 2DWY 3G2S 3G2T 3G2U 3G2V 3G2W
Enriched GO Terms of Interacting Partners?		Establishment Of Protein Localization Small GTPase Binding Clathrin-coated Vesicle Protein Transport Post-Golgi Vesicle-mediated Transport AP-1 Adaptor Complex Trans-Golgi Network Protein Localization To Plasma Membrane Golgi To Plasma Membrane Protein Transport Protein Localization To Cell Surface Intracellular Protein Transport Protein Localization To Cell Periphery Intracellular Protein Localization Regulation Of Cytokinesis, Actomyosin Contractile Ring Assembly Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Eosinophil Chemotaxis Autophagosome Lumen Golgi Vesicle Transport Golgi To Plasma Membrane Transport Protein Localization To Membrane Synaptic Vesicle Budding From Endosome Golgi Apparatus HSP90-CDC37 Chaperone Complex Positive Regulation Of Eosinophil Migration Positive Regulation Of Intracellular Protein Transport Positive Regulation Of Transport Centralspindlin Complex Regulation Of Protein Phosphorylation Positive Regulation Of Sodium:proton Antiporter Activity Ubiquitin Binding Cellular Localization Phosphatidylinositol Binding Regulation Of Phosphorylation Dolichyl-phosphate-mannose-protein Mannosyltransferase Activity Basolateral Protein Secretion Positive Regulation Of Natural Killer Cell Degranulation	Early Endosome Endosome Protein Transport Establishment Of Protein Localization Intracellular Protein Transport Vesicle-mediated Transport Intracellular Transport Cellular Localization Endosome Membrane Vacuolar Transport Establishment Of Localization In Cell Clathrin-coated Vesicle Lysosomal Transport Intracellular Protein Localization Trans-Golgi Network Recycling Endosome Endocytosis Golgi Apparatus Early Endosome Membrane Import Into Cell Post-Golgi Vesicle-mediated Transport Establishment Of Protein Localization To Vacuole Perinuclear Region Of Cytoplasm Golgi Vesicle Transport Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Protein Localization To Vacuole Protein Targeting To Vacuole Positive Regulation Of MiRNA Transcription Receptor-mediated Endocytosis Negative Regulation Of Protein Metabolic Process Trans-Golgi Network Membrane Positive Regulation Of MiRNA Metabolic Process Protein Localization To Organelle Clathrin-coated Endocytic Vesicle Membrane Protein Targeting To Lysosome Enzyme Binding Regulation Of Cell Growth Clathrin-coated Pit Ubiquitin Protein Ligase Binding Retromer Complex Binding Regulation Of Vesicle-mediated Transport Golgi To Lysosome Transport Nuclear Envelope Lumen AP-1 Adaptor Complex Establishment Of Protein Localization To Organelle Late Endosome Regulation Of Cell Cycle Regulation Of Growth Protein-containing Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?