ATXN7L3B and ENY2

Number of citations of the paper that reports this interaction (PubMedID 35271311)
106

Data Source:
BioGRID (affinity chromatography technology, affinity chromatography technology, pull down, affinity chromatography technology)

		ATXN7L3B	ENY2
Description		ataxin 7 like 3B	ENY2 transcription and export complex 2 subunit
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm	SAGA Complex Nucleus Nuclear Pore Nucleoplasm Mitochondrion Transcription Factor TFTC Complex Nuclear Pore Nuclear Basket Transcription Export Complex 2 DUBm Complex
	Molecular Function	Protein Binding	Chromatin Binding Transcription Coactivator Activity Protein Binding
	Biological Process	Regulation Of Gene Expression	Regulation Of DNA Repair Chromatin Organization Regulation Of Transcription By RNA Polymerase II Transcription Elongation By RNA Polymerase II MRNA Export From Nucleus Protein Transport Poly(A)+ MRNA Export From Nucleus Regulation Of RNA Splicing Positive Regulation Of DNA-templated Transcription MRNA Transport Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		HDL cholesterol levels in HIV infection ( 33109212) Idiopathic dilated cardiomyopathy ( 29495422) Schizophrenia ( 33169155)	Metabolite levels ( 23823483) Multiple system atrophy (pathologically confirmed) ( 27629089) Night sleep phenotypes ( 27126917)
Interacting Genes		1 interacting genes: ENY2	7 interacting genes: APP ATXN7L3B CEBPA CSTPP1 HNRNPA2B1 MCM3AP UFL1
Entrez ID		552889	56943
HPRD ID		19617	13121
Ensembl ID		ENSG00000253719	ENSG00000120533
Uniprot IDs		Q96GX2	Q9NPA8
PDB IDs			4DHX
Enriched GO Terms of Interacting Partners?		DUBm Complex Transcription Export Complex 2 Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Nuclear Pore Nuclear Basket Transcription Factor TFTC Complex SAGA Complex Poly(A)+ MRNA Export From Nucleus Negative Regulation Of Insulin Secretion Transcription Elongation By RNA Polymerase II Negative Regulation Of Peptide Secretion DNA-templated Transcription Elongation Negative Regulation Of Hormone Secretion MRNA Export From Nucleus Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Negative Regulation Of Protein Secretion RNA Export From Nucleus Nuclear Pore Negative Regulation Of Establishment Of Protein Localization Nuclear Export Negative Regulation Of Secretion By Cell Negative Regulation Of Protein Transport MRNA Transport RNA Transport Regulation Of Insulin Secretion Negative Regulation Of Secretion Regulation Of RNA Splicing Regulation Of Peptide Hormone Secretion Nucleobase-containing Compound Transport Negative Regulation Of Protein Localization Regulation Of DNA Repair Regulation Of Hormone Secretion Regulation Of Protein Secretion Nuclear Transport Nucleocytoplasmic Transport Transcription Coactivator Activity	Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Protein-containing Complex Organization Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Cell Activation Intermediate-density Lipoprotein Particle Positive Regulation Of Inflammatory Response Regulation Of Cell Activation Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Regulation Of Proteolysis Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Cell Maturation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Regulation Of Response To Endoplasmic Reticulum Stress Regulation Of Protein Catabolic Process Protein-containing Complex Regulation Of Inflammatory Response Lipoprotein Particle Memory Growth Factor Receptor Binding Main Axon Notch Signaling Pathway Chromatin Binding Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion Low-density Lipoprotein Particle Mediated Signaling Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process CHOP-C/EBP Complex Nuclear Matrix RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of Proteolysis Involved In Protein Catabolic Process Response To Vitamin B2 White Fat Cell Proliferation
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