MRGBP and ACTL6A

Number of citations of the paper that reports this interaction (PubMedID 12963728)
0

Data Source:
HPRD (in vitro)

		MRGBP	ACTL6A
Description		MRG domain binding protein	actin like 6A
Image
GO Annotations	Cellular Component	Nucleosome Nucleus Nucleoplasm NuA4 Histone Acetyltransferase Complex H4/H2A Histone Acetyltransferase Complex	Kinetochore Chromatin Nucleosome Nucleus Nucleoplasm Plasma Membrane Nuclear Matrix SWI/SNF Complex RSC-type Complex Ino80 Complex Protein-containing Complex Brahma Complex NuA4 Histone Acetyltransferase Complex NpBAF Complex GBAF Complex
	Molecular Function	Protein Binding	Chromatin Binding Transcription Coactivator Activity Protein Binding Nucleosomal DNA Binding
	Biological Process	Chromatin Organization Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Regulation Of Apoptotic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Double-strand Break Repair	Telomere Maintenance Blastocyst Formation Neural Retina Development Regulation Of DNA Replication DNA Repair Regulation Of DNA Repair DNA Recombination Chromatin Organization Chromatin Remodeling Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II DNA Damage Response Signal Transduction Nervous System Development Positive Regulation Of Cell Population Proliferation Spinal Cord Development Regulation Of Mitotic Metaphase/anaphase Transition Regulation Of Chromosome Organization Regulation Of Apoptotic Process Positive Regulation Of T Cell Differentiation Negative Regulation Of Cell Differentiation Positive Regulation Of Cell Differentiation Positive Regulation Of Myoblast Differentiation Positive Regulation Of DNA Repair Positive Regulation Of DNA-templated Transcription Regulation Of Embryonic Development System Development Regulation Of Cell Cycle Regulation Of DNA Strand Elongation Regulation Of G0 To G1 Transition Positive Regulation Of Stem Cell Population Maintenance Positive Regulation Of Telomere Maintenance In Response To DNA Damage Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Double-strand Break Repair Positive Regulation Of Double-strand Break Repair Regulation Of Nucleotide-excision Repair
Pathways		HATs acetylate histones	HATs acetylate histones RMTs methylate histone arginines UCH proteinases DNA Damage Recognition in GG-NER RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known Regulation of MITF-M-dependent genes involved in pigmentation Regulation of MITF-M-dependent genes involved in pigmentation Regulation of endogenous retroelements by Piwi-interacting RNAs (piRNAs) Formation of the canonical BAF (cBAF) complex Formation of the polybromo-BAF (pBAF) complex Formation of the embryonic stem cell BAF (esBAF) complex Formation of the non-canonical BAF (ncBAF) complex Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF) Formation of neuronal progenitor and neuronal BAF (npBAF and nBAF)
Drugs
Diseases
GWAS			Pars opercularis volume ( 31530798)
Interacting Genes		25 interacting genes: ACTB ACTL6A BRD8 DAPK1 DMAP1 HSPB1 ING1 KRTAP1-1 KRTAP10-7 KRTAP17-1 KRTAP5-7 LRRK2 MEAF6 MFHAS1 MORF4L1 MORF4L2 MSL1 NBPF19 NOTCH2NLA RUVBL1 SH3BP4 TRRAP TUBB VAV2 YEATS4	17 interacting genes: ARHGDIA CDK2 CDK9 ERO1B EWSR1 FLII MRGBP MYC OGT POLR2A PTEN RELA RUVBL1 SMARCA2 SMARCA4 TRRAP UBC
Entrez ID		55257	86
HPRD ID		16646	05389
Ensembl ID		ENSG00000101189	ENSG00000136518
Uniprot IDs		Q9NV56	O96019
PDB IDs		2N1D	6LTJ 7VDV 7Y8R 8QR1 8X15 8X19 8X1C 8XVG 8XVT 9C4B 9C57 9C62 9C6N
Enriched GO Terms of Interacting Partners?		NuA4 Histone Acetyltransferase Complex Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of DNA Recombination Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Double-strand Break Repair Nucleosome Regulation Of DNA Recombination Positive Regulation Of DNA Repair Regulation Of Double-strand Break Repair Regulation Of DNA Repair Positive Regulation Of DNA Metabolic Process Regulation Of Cellular Response To Stress Chromatin Organization Regulation Of DNA Metabolic Process Swr1 Complex Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Cell Cycle Positive Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of RNA Metabolic Process Chromatin Remodeling Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Nuclear Matrix Positive Regulation Of Stem Cell Population Maintenance Intermediate Filament Regulation Of Stem Cell Population Maintenance Brahma Complex NpBAF Complex GBAF Complex Positive Regulation Of Telomere Maintenance In Response To DNA Damage RSC-type Complex Ino80 Complex Negative Regulation Of GTPase Activity Regulation Of DNA Strand Elongation Syntaxin-1 Binding Structural Constituent Of Cytoskeleton Sin3-type Complex Regulation Of Synaptic Vesicle Endocytosis Regulation Of Gene Expression Regulation Of DNA-templated Transcription Regulation Of DNA Replication Regulation Of RNA Biosynthetic Process DNA Repair Regulation Of Nucleotide-excision Repair Regulation Of Macromolecule Biosynthetic Process	Chromatin Organization Positive Regulation Of DNA Metabolic Process Regulation Of DNA Metabolic Process Nucleoplasm Positive Regulation Of Double-strand Break Repair Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of DNA Repair Positive Regulation Of RNA Metabolic Process Regulation Of Cell Cycle Positive Regulation Of DNA Repair Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Double-strand Break Repair Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cellular Response To Stress Positive Regulation Of Biosynthetic Process Regulation Of Stem Cell Population Maintenance Regulation Of RNA Metabolic Process Nucleus Chromatin Remodeling Regulation Of Nucleobase-containing Compound Metabolic Process NuA4 Histone Acetyltransferase Complex Regulation Of Transcription By RNA Polymerase II Regulation Of Chromosome Organization Positive Regulation Of Macromolecule Metabolic Process ATP-dependent Activity, Acting On DNA Nucleosome Array Spacer Activity Positive Regulation Of Metabolic Process Positive Regulation Of Double-strand Break Repair Via Homologous Recombination Positive Regulation Of Stem Cell Population Maintenance Regulation Of G1/S Transition Of Mitotic Cell Cycle Positive Regulation Of MiRNA Transcription Regulation Of Cell Cycle G1/S Phase Transition Positive Regulation Of MiRNA Metabolic Process Regulation Of Gene Expression BBAF Complex DNA-templated Transcription Regulation Of Macromolecule Biosynthetic Process Regulation Of MiRNA Transcription Positive Regulation Of DNA Recombination Regulation Of Primary Metabolic Process Swr1 Complex Regulation Of Double-strand Break Repair Via Homologous Recombination NpBAF Complex GBAF Complex Regulation Of MiRNA Metabolic Process Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II
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