STEAP3 and TPT1

Number of citations of the paper that reports this interaction (PubMedID 15319436)
0

Data Source:
HPRD (two hybrid, in vitro)

		STEAP3	TPT1
Description		STEAP3 metalloreductase	tumor protein, translationally-controlled 1
Image
GO Annotations	Cellular Component	Cytoplasm Endosome Multivesicular Body Plasma Membrane Endosome Membrane Membrane	Spindle Pole Extracellular Space Nucleus Nucleoplasm Cytoplasm Multivesicular Body Cytosol Cytoplasmic Microtubule Extracellular Exosome
	Molecular Function	Protein Binding Cupric Reductase (NADH) Activity Oxidoreductase Activity Heme Binding Identical Protein Binding Metal Ion Binding Ferric-chelate Reductase (NADPH) Activity FAD Binding	RNA Binding Calcium Ion Binding Protein Binding DNA-binding Transcription Factor Binding
	Biological Process	Monoatomic Ion Transport Iron Ion Transport Apoptotic Process Protein Secretion Copper Ion Import	Calcium Ion Transport Intracellular Calcium Ion Homeostasis Response To Virus Stem Cell Population Maintenance Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Negative Regulation Of Ectoderm Development
Pathways		TP53 Regulates Transcription of Genes Involved in Cytochrome C Release CDC42 GTPase cycle RHOD GTPase cycle RHOQ GTPase cycle RHOJ GTPase cycle RHOF GTPase cycle Transferrin endocytosis and recycling
Drugs			Calcium citrate Calcium Phosphate Calcium phosphate dihydrate
Diseases
GWAS		Cocaine dependence ( 23958962) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Renal cell carcinoma x sex interaction ( 31231134)	Type 2 diabetes ( 25760438)
Interacting Genes		6 interacting genes: BAD BNIP3L MTDH PKMYT1 SETD7 TPT1	30 interacting genes: APP ATP1A1 ATP1A2 BCL2L1 CALM1 CEBPA DBN1 EEF1A1 EEF1B2 EEF1D FANCA HSPB1 IKBKG LIG4 MCL1 MCPH1 MDM2 MLC1 NKX3-1 NOTCH3 PER2 PLK1 RBBP6 SNX6 SPP1 STEAP3 TRIP13 TUBB2A USP40 VHL
Entrez ID		55240	7178
HPRD ID		10285	15979
Ensembl ID		ENSG00000115107	ENSG00000133112
Uniprot IDs		B8ZZX6 Q658P3	A0A0B4J2C3 P13693
PDB IDs		2VNS 2VQ3	1YZ1 2HR9 3EBM 4Z9V 5O9L 5O9M 6IZB 6IZE
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Autophagy Regulation Of Mitochondrial Membrane Potential Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To Osmotic Stress Regulation Of Mitochondrial Membrane Permeability Apoptotic Mitochondrial Changes Negative Regulation Of Programmed Cell Death Negative Regulation Of Apoptotic Process Regulation Of Membrane Permeability Regulation Of Autophagy Negative Regulation Of Ectoderm Development Regulation Of Programmed Cell Death Regulation Of Cellular Response To Stress Regulation Of Apoptotic Process BAD-BCL-2 Complex Positive Regulation Of Catabolic Process Positive Regulation Of Type B Pancreatic Cell Development Mitochondrial Membrane Organization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Negative Regulation Of G2/MI Transition Of Meiotic Cell Cycle Cellular Response To Oxygen Levels Regulation Of Intrinsic Apoptotic Signaling Pathway Peptidyl-lysine Dimethylation Positive Regulation Of Mitochondrial Membrane Potential Mitochondrial Outer Membrane Intercellular Canaliculus Regulation Of G2/MI Transition Of Meiotic Cell Cycle Negative Regulation Of Meiotic Cell Cycle Phase Transition Peptidyl-lysine Monomethylation Regulation Of Type B Pancreatic Cell Development Cellular Response To Nicotine Histone H3K4 Monomethyltransferase Activity Nucleolus Mitochondrial Outer Membrane Permeabilization Mitochondrion Organization Cysteine-type Endopeptidase Activator Activity Mitochondrial Protein Catabolic Process Positive Regulation Of Membrane Potential Negative Regulation Of Mitochondrial Membrane Potential Heterochromatin Organization Response To Hypoxia Regulation Of Cellular Response To Osmotic Stress Negative Regulation Of Membrane Potential Response To Decreased Oxygen Levels Regulation Of Response To Osmotic Stress Positive Regulation Of Mitochondrial Membrane Permeability Involved In Apoptotic Process Mitochondrial Envelope Response To Oxygen Levels Lamin Binding Mitochondrial Outer Membrane Permeabilization Involved In Programmed Cell Death	Eukaryotic Translation Elongation Factor 1 Complex Regulation Of Intrinsic Apoptotic Signaling Pathway Cellular Response To Stress Response To Stress DNA Damage Response Response To Steroid Hormone Regulation Of Autophagy Intracellular Signal Transduction Regulation Of Blood Circulation Regulation Of System Process Regulation Of Apoptotic Signaling Pathway Translation Elongation Factor Activity Regulation Of Neurotransmitter Uptake Cell Communication By Electrical Coupling Regulation Of Cell Cycle Cellular Response To Ionizing Radiation Negative Regulation Of Blood Circulation Response To Radiation Negative Regulation Of Apoptotic Process Nucleus Negative Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Amyloid Fibril Formation Regulation Of Glutamate Uptake Involved In Transmission Of Nerve Impulse Response To Metal Ion Identical Protein Binding Regulation Of Programmed Cell Death Protein Heterodimerization Activity Positive Regulation Of Proteolysis Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Response To Stress Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Protein-containing Complex Response To Cytokine Negative Regulation Of RNA Biosynthetic Process Regulation Of Biological Quality Negative Regulation Of DNA-templated Transcription Response To Peptide Regulation Of Transport Steroid Hormone Binding P-type Potassium Transmembrane Transporter Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway BH3 Domain Binding Negative Regulation Of Apoptotic Signaling Pathway P-type Sodium:potassium-exchanging Transporter Activity Response To Glycoside Regulation Of Neuron Apoptotic Process Cytosol Sodium Ion Binding
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