RMDN3 and SLC13A3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RMDN3	SLC13A3
Description		regulator of microtubule dynamics 3	solute carrier family 13 member 3
Image
GO Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Spindle Cytoskeleton Microtubule Spindle Microtubule Membrane Organelle Membrane Contact Site Intercellular Bridge Mitotic Spindle Pole Presynapse Postsynapse Glutamatergic Synapse	Plasma Membrane Membrane Basolateral Plasma Membrane Extracellular Exosome
	Molecular Function	Protein Binding Microtubule Binding	Dicarboxylic Acid Transmembrane Transporter Activity Protein Binding Citrate Transmembrane Transporter Activity Alpha-ketoglutarate Transmembrane Transporter Activity Succinate Transmembrane Transporter Activity Symporter Activity High-affinity Sodium:dicarboxylate Symporter Activity Solute:sodium Symporter Activity Sodium:dicarboxylate Symporter Activity Transmembrane Transporter Activity Glutathione Transmembrane Transporter Activity
	Biological Process	Intracellular Calcium Ion Homeostasis Apoptotic Process Cell Differentiation	Monoatomic Ion Transport Sodium Ion Transport Dicarboxylic Acid Transport Lipid Transport Alpha-ketoglutarate Transport Citrate Transport Glutathione Transmembrane Transport Sodium Ion Transmembrane Transport Transmembrane Transport Succinate Transmembrane Transport Transport Across Blood-brain Barrier
Pathways			SLC-mediated transport of organic anions
Drugs
Diseases
GWAS		Anxiety and stress-related disorders ( 31116379) Malaria ( 31844061) Refractive error ( 32231278)	Brain volume in infants (white matter) ( 28763065) Chronic kidney disease ( 24351856) Glomerular filtration rate ( 24351856) Gout ( 22179738) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Mild age-related type 2 diabetes ( 34737425) Serum metabolite levels ( 33031748) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		26 interacting genes: CYB561D2 EGFL8 EMP3 FAM3C GIMAP1 LHFPL5 NRM PELI2 PLP1 PSEN1 SLC13A3 SLC30A8 STX2 STX3 TF TFRC TMEM100 TMEM140 TMEM147 TMEM203 TMEM243 VAMP3 VAPA VKORC1 YWHAB YWHAG	11 interacting genes: ARL13B CISD2 CREB3L1 CYB5R3 ERGIC3 FAM209A GPX8 LEUTX LMNA RMDN3 TSC2
Entrez ID		55177	64849
HPRD ID		07687	10450
Ensembl ID		ENSG00000137824	ENSG00000158296
Uniprot IDs		Q96TC7	B4DF27 Q8WWT9
PDB IDs		7CC7	8UVC 8UVD 8UVE 8UVF 8UVG 8UVI
Enriched GO Terms of Interacting Partners?		Membrane Organelle Localization By Membrane Tethering Membrane Docking SNAP Receptor Activity SNARE Complex Establishment Of Protein Localization Myeloid Leukocyte Differentiation HFE-transferrin Receptor Complex Membrane Fusion Vesicle Docking Intracellular Protein Localization Clathrin-coated Endocytic Vesicle Membrane Vesicle Positive Regulation Of Receptor Recycling Cytoplasmic Vesicle Intracellular Monoatomic Cation Homeostasis Intracellular Monoatomic Ion Homeostasis Inorganic Ion Homeostasis Vacuole Vesicle Fusion Organelle Membrane Fusion Myeloid Cell Differentiation Melanosome Secretory Granule Perinuclear Region Of Cytoplasm Regulation Of Receptor Recycling Nuclear Membrane Monoatomic Cation Homeostasis Monoatomic Ion Homeostasis Endoplasmic Reticulum Membrane Multicellular Organismal-level Iron Ion Homeostasis Positive Regulation Of Signaling Positive Regulation Of Coagulation Organelle Fusion Intracellular Chemical Homeostasis Response To Iron Ion Vesicle Organization Recycling Endosome Early Endosome Endoplasmic Reticulum Amide Transport Negative Regulation Of Core Promoter Binding High-affinity Sodium:dicarboxylate Symporter Activity Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Chemical Homeostasis Plasma Membrane Bounded Cell Projection Organization Regulation Of Protein Localization To Nucleus Metal Ion Transport Protein Binding Protein Sequestering Activity
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