CENPQ and BRME1

Number of citations of the paper that reports this interaction (PubMedID 19060904)
32

Data Source:
BioGRID (two hybrid)

		CENPQ	BRME1
Description		centromere protein Q	break repair meiotic recombinase recruitment factor 1
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GO Annotations	Cellular Component	Chromosome, Centromeric Region Inner Kinetochore Nucleus Nucleoplasm Chromosome Cytosol Actin Cytoskeleton	Chromosome
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Chromosome Segregation Metaphase Chromosome Alignment Positive Regulation Of Protein Localization To Kinetochore	Female Meiosis I Spermatogenesis Meiotic Cell Cycle Double-strand Break Repair Involved In Meiotic Recombination
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins Deposition of new CENPA-containing nucleosomes at the centromere Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation
Drugs
Diseases
GWAS		Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494)
Interacting Genes		12 interacting genes: AARD ABI2 ABI3 APP BRME1 CENPU EMILIN1 HDAC7 KDM1A PLK1 SIKE1 SNX2	35 interacting genes: ADAMTSL4 AIMP2 AKAP8L APP C19orf25 CENPQ COPS4 CTNNAL1 CYSRT1 EWSR1 FAM9B FBXO25 GDF15 GPS2 HAUS3 HOMER1 IKBKG KRT31 KRT34 KRT38 KRT40 KRTAP10-3 KRTAP10-7 KRTAP10-8 KRTAP10-9 KRTAP5-9 NBPF19 NOTCH2NLA PSMA6 RABL6 RUNX1T1 STXBP1 TRIM23 TSC22D3 VCL
Entrez ID		55166	79173
HPRD ID		10788	14415
Ensembl ID		ENSG00000031691	ENSG00000132016
Uniprot IDs		Q7L2Z9	K7EMZ7 Q0VDD7
PDB IDs		7PB8 7PKN 7QOO 7R5S 7R5V 7XHN 7XHO 7YWX 7YYH	8A51
Enriched GO Terms of Interacting Partners?		Cell Projection Morphogenesis SCAR Complex Actin-based Cell Projection Identical Protein Binding Insulin Receptor Binding Regulation Of Postsynapse Organization Dendritic Spine Neuron Maturation Cell Junction Organization Lamellipodium Regulation Of Lamellipodium Assembly Dendritic Shaft Regulation Of Dendritic Spine Morphogenesis Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To CAMP Regulation Of Lamellipodium Organization Peptidyl-tyrosine Phosphorylation Regulation Of Plasma Membrane Bounded Cell Projection Organization Epigenetic Regulation Of Gene Expression Regulation Of Cell Projection Organization Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Synapse Organization Anatomical Structure Morphogenesis Endosome To Plasma Membrane Transport Vesicle Negative Regulation Of Signal Transduction Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Developmental Process Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Negative Regulation Of Cellular Component Organization Phosphorylation Synaptonemal Complex Disassembly Protein Phosphorylation Nuclear Division Golgi Inheritance Chromosome Regulation Of Double-strand Break Repair Via Homologous Recombination Signaling Adaptor Activity	Intermediate Filament Keratin Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Cytosol Intermediate Filament Cytoskeleton Organization Structural Molecule Activity Intermediate Filament-based Process Epidermis Development Regulation Of Dendritic Spine Maintenance Costamere
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