TMEM33 and GUF1

		TMEM33	GUF1
Description		transmembrane protein 33	GTP binding elongation factor GUF1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Melanosome	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane
	Molecular Function	Protein Binding	Nucleotide Binding GTPase Activity GTP Binding Hydrolase Activity Ribosome Binding Mitochondrial Ribosome Binding
	Biological Process	Immune System Process Response To Endoplasmic Reticulum Stress Innate Immune Response Membrane Organization Endoplasmic Reticulum Tubular Network Organization Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of PERK-mediated Unfolded Protein Response	Translation Positive Regulation Of Translation
Pathways
Drugs
Diseases
GWAS		Helping behaviour (self reported) ( 29324852) Neurociticism ( 29500382)	Metabolite levels ( 23823483) Refractive error ( 32231278) Systolic blood pressure ( 26969751)
Interacting Genes		11 interacting genes: CCR9 DCAF4L1 GUF1 MTNR1A OR5F1 RHOH RPL9 RPS14 SIX6 SLC29A2 YIPF7	3 interacting genes: DCAF4L1 DSCAM TMEM33
Entrez ID		55161	60558
HPRD ID		07680	07821
Ensembl ID		ENSG00000109133	ENSG00000151806
Uniprot IDs		P57088	Q8N442
PDB IDs
Enriched GO Terms of Interacting Partners?		Cytidine Transmembrane Transporter Activity Uracil Transmembrane Transport Thymine Transport Uridine Transmembrane Transport Inosine Transport Pyrimidine Nucleobase Transmembrane Transport Nucleobase Transmembrane Transporter Activity Cytidine Transport Uracil Transmembrane Transporter Activity Adenine Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transport Guanine Transmembrane Transporter Activity Pyrimidine Nucleoside Transport Guanine Transport Guanine Transmembrane Transport Adenosine Transport Hypoxanthine Transport Nucleoside Transmembrane Transporter Activity Purine Nucleoside Transmembrane Transporter Activity Uridine Transmembrane Transporter Activity G Protein-coupled Receptor Activity Melatonin Receptor Activity Cytoplasmic Translation Translation Cytosolic Ribosome CD8-positive, Gamma-delta Intraepithelial T Cell Differentiation Nucleoside Transmembrane Transport Adenine Transport Nucleoside Transport Pyrimidine Nucleobase Transport Structural Constituent Of Ribosome Mitochondrial Ribosome Binding Kinase Inhibitor Activity T Cell Differentiation Purine Nucleobase Transmembrane Transport Vesicle Fusion With Golgi Apparatus Mast Cell Activation Membrane Purine Nucleobase Transport Ribosome	Post-embryonic Retina Morphogenesis In Camera-type Eye Positive Regulation Of Axon Extension Involved In Axon Guidance Netrin Receptor Binding Regulation Of Endoplasmic Reticulum Tubular Network Organization Positive Regulation Of PERK-mediated Unfolded Protein Response Netrin-activated Signaling Pathway Regulation Of Axon Extension Involved In Axon Guidance Dendrite Self-avoidance Camera-type Eye Photoreceptor Cell Differentiation Dendritic Spine Development Regulation Of PERK-mediated Unfolded Protein Response Positive Regulation Of IRE1-mediated Unfolded Protein Response Positive Regulation Of Endoplasmic Reticulum Unfolded Protein Response Regulation Of IRE1-mediated Unfolded Protein Response Eye Photoreceptor Cell Differentiation Photoreceptor Cell Differentiation Endoplasmic Reticulum Tubular Network Organization Retina Layer Formation Cul4-RING E3 Ubiquitin Ligase Complex
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