TMEM70 and RAB2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TMEM70	RAB2A
Description		transmembrane protein 70	RAB2A, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Mitochondrion Mitochondrial Inner Membrane Membrane Mitochondrial Crista Mitochondrial Membrane	Golgi Membrane Autophagosome Membrane Acrosomal Vesicle Nucleus Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Cytoplasmic Vesicle Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Extracellular Exosome
	Molecular Function	Protein Binding Mitochondrial Proton-transporting ATP Synthase Complex Binding	Nucleotide Binding GTPase Activity G Protein Activity Protein Binding GTP Binding Hydrolase Activity GDP Binding Metal Ion Binding
	Biological Process	Mitochondrial Respiratory Chain Complex I Assembly Mitochondrial Proton-transporting ATP Synthase Complex Assembly Protein Complex Oligomerization Protein Homooligomerization	Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Golgi Organization Protein Transport Vesicle-mediated Transport Macroautophagy Autophagosome-lysosome Fusion
Pathways			Golgi Cisternae Pericentriolar Stack Reorganization RAB geranylgeranylation
Drugs
Diseases		Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS		Low density lipoprotein cholesterol levels ( 32154731) Metabolite levels ( 23823483)	Aspartate aminotransferase levels ( 33547301) Autoimmune thyroid disease ( 32581359) Estimated glomerular filtration rate ( 31152163) Low density lipoprotein cholesterol levels ( 32154731) Neutrophil count ( 32888494) Systemic sclerosis ( 31672989) Total cholesterol levels ( 29083408)
Interacting Genes		5 interacting genes: BDKRB2 LPAR3 PHC2 RAB2A RAF1	32 interacting genes: ASPH BLZF1 CBFB CCDC125 CEBPA CFL2 CPA4 FAM114A1 FAM114A2 FRMD1 GAA GAPDH GARIN4 GARIN6 GDI2 GOLGA2 GORASP2 HES6 ICA1 MAPK6 MAPKAPK3 OTOS PMAIP1 PRKCI RBSN RGS2 RP1 SGSM2 STAMBPL1 TBC1D25 TMEM70 TRIM7
Entrez ID		54968	5862
HPRD ID		07923	01539
Ensembl ID		ENSG00000175606	ENSG00000104388
Uniprot IDs		Q9BUB7	P61019
PDB IDs			1Z0A
Enriched GO Terms of Interacting Partners?
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