CT55 and SNF8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CT55	SNF8
Description		cancer/testis antigen 55	SNF8 subunit of ESCRT-II
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Cilium Cytoplasmic Vesicle Motile Cilium Sperm Flagellum Cell Projection	ESCRT II Complex Nucleus Nucleoplasm Transcription Regulator Complex Cytoplasm Endosome Cytosol Plasma Membrane Endosome Membrane Membrane Late Endosome Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Extracellular Exosome
	Molecular Function	Protein Binding	Protein Binding Lipid Binding Channel Regulator Activity Protein Homodimerization Activity
	Biological Process	Spermatogenesis	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression Protein Transport Macroautophagy Endocytic Recycling Multivesicular Body Assembly Regulation Of Protein Catabolic Process Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of MAP Kinase Activity Early Endosome To Late Endosome Transport Positive Regulation Of Protein Catabolic Process Regulation Of Protein Complex Stability Multivesicular Body Sorting Pathway Membrane Fission Positive Regulation Of Exosomal Secretion
Pathways			Endosomal Sorting Complex Required For Transport (ESCRT) HCMV Late Events
Drugs
Diseases
GWAS			Coronary heart disease ( 21378990) Hip circumference adjusted for BMI ( 34021172) Type 2 diabetes ( 29358691)
Interacting Genes		32 interacting genes: AIRIM BFSP2 CABP5 CATSPERT CPNE2 DES EXOC7 FAAP20 GFAP GPRASP3 KIAA0753 KLC3 KLHL42 KYNU LYPLAL1 MBD3 MEMO1 MEOX2 P4HA3 PAX7 PIH1D2 PRPH SAMD11 SHC3 SNF8 SPG21 TFIP11 TLE5 TXLNB VIM ZNF177 ZNF559-ZNF177	26 interacting genes: ADORA1 AKAP9 CHMP6 CLP1 CT55 DVL2 ELL FANCL GLYCTK GOLGA2 HMOX1 KDM1A NIF3L1 PRMT6 RILP SMARCD1 SUOX SUV39H2 TRIM54 TSG101 TXLNA UBC VAC14 VPS25 VPS36 YWHAE
Entrez ID		54967	11267
HPRD ID		06534	16847
Ensembl ID		ENSG00000169551	ENSG00000159210
Uniprot IDs		Q8WUE5	Q96H20
PDB IDs			2ZME 3CUQ
Enriched GO Terms of Interacting Partners?		Intermediate Filament Organization Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Structural Constituent Of Cytoskeleton Intermediate Filament Intermediate Filament Cytoskeleton Lens Fiber Cell Development Bergmann Glial Cell Differentiation Protein Binding Astrocyte Development	Endosome Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Sorting Pathway Late Endosome To Vacuole Transport Via Multivesicular Body Sorting Pathway Multivesicular Body Organization Endosome Organization Multivesicular Body Assembly Late Endosome To Vacuole Transport Negative Regulation Of Epidermal Growth Factor-activated Receptor Activity Membrane Fission Negative Regulation Of Protein Tyrosine Kinase Activity Negative Regulation Of Signaling Receptor Activity Protein Transport To Vacuole Involved In Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Late Endosome Membrane Negative Regulation Of Peptidyl-tyrosine Phosphorylation Macroautophagy Vacuolar Transport Regulation Of Protein Tyrosine Kinase Activity ESCRT II Complex Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Regulation Of Signaling Receptor Activity Vesicle-mediated Transport Endosomal Transport Endosome Membrane Autophagy Vesicle Organization Establishment Of Protein Localization To Vacuole Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Protein Kinase Activity Regulation Of ERBB Signaling Pathway Negative Regulation Of Kinase Activity Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Catabolic Process Negative Regulation Of Metabolic Process Protein Localization To Vacuole Regulation Of Exosomal Secretion Establishment Of Protein Localization Viral Budding Via Host ESCRT Complex Organelle Assembly Negative Regulation Of Protein Phosphorylation Histone H3 Methyltransferase Activity Viral Budding Regulation Of Signal Transduction By P53 Class Mediator Endosome Viral Release From Host Cell Negative Regulation Of Phosphorylation Lysosomal Transport Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Microtubule Nucleation Ubiquitin Protein Ligase Binding
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