ZCCHC2 and PIGN

		ZCCHC2	PIGN
Description		zinc finger CCHC-type containing 2	phosphatidylinositol glycan anchor biosynthesis class N
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	Nucleic Acid Binding Zinc Ion Binding Phosphatidylinositol Binding Metal Ion Binding	Transferase Activity Mannose-ethanolamine Phosphotransferase Activity
	Biological Process		GPI Anchor Biosynthetic Process
Pathways			Synthesis of glycosylphosphatidylinositol (GPI)
Drugs
Diseases
GWAS		A body shape index ( 34021172) Asthma (age of onset) ( 31036433) Asthma (childhood onset) ( 31036433) Bipolar disorder ( 31043756 33263727) Breastfeeding duration ( 25475840) Chronotype ( 30696823) Cognitive function in longevity ( 33607172) Menopause (age at onset) ( 29773799) Morning person ( 30696823) Pulse pressure ( 30224653) Serum albumin levels ( 23022100) Waist circumference adjusted for body mass index ( 34021172)	Metabolite levels ( 23823483)
Interacting Genes		9 interacting genes: ERCC1 HMSD MDM4 PHLPP1 PIGN RELCH RNF10 SERPINB7 SHANK3	3 interacting genes: FJX1 SERPINB7 ZCCHC2
Entrez ID		54877	23556
HPRD ID		11696	12085
Ensembl ID		ENSG00000141664	ENSG00000197563
Uniprot IDs		Q9BRD4 Q9C0B9	A0A1W2PNR0 A0A1W2PPR7 A0A1W2PQA9 O95427
PDB IDs
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Platelet-derived Growth Factor Production Regulation Of Platelet-derived Growth Factor Production Positive Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta1 Production Positive Regulation Of Cell Proliferation Involved In Kidney Development Regulation Of Glomerular Mesangial Cell Proliferation Positive Regulation Of Transforming Growth Factor Beta Production Positive Regulation Of Collagen Biosynthetic Process Retina Layer Formation Regulation Of Collagen Biosynthetic Process Regulation Of Collagen Metabolic Process Serine-type Endopeptidase Inhibitor Activity
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