TRIM44 and MORN4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRIM44	MORN4
Description		tripartite motif containing 44	MORN repeat containing 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Cytoplasm	Cytoplasm Stereocilium Stereocilium Tip Filopodium Tip Cell Projection Actin-based Cell Projection
	Molecular Function	Protein Binding Zinc Ion Binding Metal Ion Binding Ubiquitin Protein Ligase Activity	Protein Binding
	Biological Process	Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Defense Response To Virus By Host Regulation Of Gene Expression Innate Immune Response Positive Regulation Of DNA-templated Transcription Protein Stabilization Negative Regulation Of Protein K48-linked Ubiquitination Positive Regulation Of Non-canonical NF-kappaB Signal Transduction	Response To Axon Injury
Pathways
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Photic sneeze reflex ( 27182965) Response to antipsychotic therapy (extrapyramidal side effects) ( 19875103)	Bell's palsy ( 33602968)
Interacting Genes		10 interacting genes: APP FBXO7 HINFP MORN4 NEDD4 PBX3 PICK1 TRIM10 TRIM69 UBC	30 interacting genes: APOA5 BEND3 CRTAC1 DNAJC9 EXOSC8 F2RL1 GOPC GUCD1 HMMR INO80E KRT25 KRT27 MAGI2 NUTM1 NUTM2F NYAP2 PLAGL2 RHOQ SEPTIN11 SEPTIN6 SNCB SSX2IP SYTL2 TCF12 TCF4 TRIM23 TRIM44 WASHC1 WBP11 ZNF131
Entrez ID		54765	118812
HPRD ID		15561	16584
Ensembl ID		ENSG00000166326	ENSG00000171160
Uniprot IDs		Q96DX7	A6XB87 Q8NDC4
PDB IDs
Enriched GO Terms of Interacting Partners?		Amyloid-beta Complex Innate Immune Response Growth Cone Lamellipodium Neuron Projection Organization Defense Response To Symbiont Regulation Of Response To Calcium Ion Response To Stress Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Receptor-mediated Endocytosis Positive Regulation Of Receptor Internalization Glial Cell Development Protein Modification By Small Protein Conjugation Ubiquitin-protein Transferase Activity Protein Ubiquitination Formation Of Structure Involved In A Symbiotic Process Posterior Compartment Specification Anterior Compartment Pattern Formation Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Defense Response To Other Organism G Protein-coupled Receptor Binding Regulation Of Receptor Internalization Endocytic Vesicle Membrane Adult Locomotory Behavior Post-translational Protein Modification Ubiquitin Protein Ligase Activity Acetylcholine Receptor Activator Activity Lipoprotein Particle Positive Regulation Of Protein Import Channel Inhibitor Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Enzyme Binding Trans-Golgi Network Membrane Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Protein Modification Process Ubiquitin Ligase Complex Phosphothreonine Residue Binding Ubiquitin Binding Lewy Body Core Response To Norepinephrine	Positive Regulation Of Pseudopodium Assembly Cell Division Site Septin Ring Septin Complex Golgi-associated Vesicle Membrane
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