SCAND2P and ISG20

		SCAND2P	ISG20
Description		SCAN domain containing 2 pseudogene	interferon stimulated exonuclease gene 20
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus	P-body Nucleus Nucleoplasm Nucleolus Cytoplasm Cajal Body PML Body
	Molecular Function	DNA-binding Transcription Factor Activity	3'-5'-RNA Exonuclease Activity Nucleic Acid Binding RNA Binding Nuclease Activity Exonuclease Activity Single-stranded DNA 3'-5' DNA Exonuclease Activity Exoribonuclease II Activity Hydrolase Activity U1 SnRNA Binding U2 SnRNA Binding U3 SnoRNA Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Immune System Process DNA Metabolic Process DNA Catabolic Process RRNA Processing RNA Processing RNA Catabolic Process Response To Virus Negative Regulation Of Viral Genome Replication Innate Immune Response Defense Response To Virus
Pathways			Interferon alpha/beta signaling
Drugs			Uridine monophosphate
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Schizophrenia ( 29483656)	Adult hearing aid use ( 31564434) Adult hearing difficulty ( 31564434) Age-related hearing impairment ( 27764096 34108613) Age-related hearing impairment (low/mid frequency) ( 31645637) Dupuytren's disease ( 21732829 28886342) Hip circumference adjusted for BMI ( 34021172) Mean corpuscular hemoglobin ( 32888494) Night sleep phenotypes ( 27126917) Obesity-related traits ( 23251661) Serum omega-6 polyunsaturated fatty acid concentration in metabolic syndrome ( 31991592) Serum total polyunsaturated fatty acid concentration in metabolic syndrome ( 31991592)
Interacting Genes		5 interacting genes: APP CHRM5 ISG20 MEF2A SLC28A1	2 interacting genes: NRG1 SCAND2P
Entrez ID		54581	3669
HPRD ID		18021	05169
Ensembl ID			ENSG00000172183
Uniprot IDs			H0YMM4 Q96AZ6
PDB IDs			1WLJ 7UGB
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Amyloid-beta Complex PTB Domain Binding Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Regulation Of Response To Calcium Ion Axon Midline Choice Point Recognition Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Amyloid Fibril Formation Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To Norepinephrine Stimulus Lipoprotein Particle Growth Factor Receptor Binding Main Axon Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Astrocyte Activation Involved In Immune Response Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Cellular Response To Metal Ion Low-density Lipoprotein Particle Mediated Signaling G Protein-coupled Acetylcholine Receptor Activity Regulation Of Phosphatidylinositol Dephosphorylation Single-stranded DNA 3'-5' DNA Exonuclease Activity Exoribonuclease II Activity ERK5 Cascade Ventricular Cardiac Myofibril Assembly Cytidine Transmembrane Transporter Activity Pyrimidine- And Adenosine-specific:sodium Symporter Activity Nucleoside:sodium Symporter Activity Uridine Transmembrane Transport Azole Transmembrane Transporter Activity Cytidine Transport Purine Nucleobase Transmembrane Transporter Activity Pyrimidine Nucleoside Transport Nucleoside Transmembrane Transporter Activity Nucleoside Import Across Plasma Membrane Uridine Transmembrane Transporter Activity Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway	Positive Regulation Of Peptidyl-tyrosine Autophosphorylation Activation Of Protein Kinase B Activity Ventricular Cardiac Muscle Cell Differentiation ErbB-3 Class Receptor Binding Positive Regulation Of Protein Autophosphorylation ERBB2-ERBB3 Signaling Pathway ERBB3 Signaling Pathway ERBB2-ERBB4 Signaling Pathway Endocardial Cell Differentiation ERBB4 Signaling Pathway Nickel Cation Binding ERBB4-ERBB4 Signaling Pathway Cardiac Muscle Cell Myoblast Differentiation Cardioblast Differentiation Regulation Of Protein Autophosphorylation Ventricular Trabecula Myocardium Morphogenesis Protein Tyrosine Kinase Activator Activity Transmembrane Receptor Protein Tyrosine Kinase Activator Activity Stem Cell Development Mammary Gland Development Positive Regulation Of Heart Growth Endothelial Cell Differentiation Heart Trabecula Morphogenesis Cardiac Muscle Cell Differentiation Myoblast Differentiation Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Peripheral Nervous System Development Negative Regulation Of Striated Muscle Cell Apoptotic Process Neural Crest Cell Development ERBB2 Signaling Pathway Positive Regulation Of Cardiac Muscle Cell Proliferation Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Postsynaptic Neurotransmitter Receptor Internalization Chemorepellent Activity Activation Of Protein Kinase Activity Regulation Of Cardiac Muscle Cell Proliferation Negative Chemotaxis Positive Regulation Of Organ Growth Ventricular Cardiac Muscle Tissue Morphogenesis Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cardiocyte Differentiation Positive Regulation Of Striated Muscle Cell Differentiation Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Peptidyl-tyrosine Phosphorylation Negative Regulation Of Muscle Cell Apoptotic Process Cardiac Muscle Tissue Morphogenesis Receptor Tyrosine Kinase Binding Regulation Of Heart Growth Regulation Of Receptor Internalization Striated Muscle Cell Differentiation
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