SETD4 and CIAO2A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SETD4	CIAO2A
Description		SET domain containing 4	cytosolic iron-sulfur assembly component 2A
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol	Nucleoplasm Cytoplasm Cytosol Cytosolic [4Fe-4S] Assembly Targeting Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Methyltransferase Activity Protein-lysine N-methyltransferase Activity Transferase Activity Histone Methyltransferase Activity Histone H4K20 Methyltransferase Activity Histone H3K4 Methyltransferase Activity Histone H3K36 Methyltransferase Activity Histone H4K20me Methyltransferase Activity Histone H4K20 Monomethyltransferase Activity Histone H3K4 Monomethyltransferase Activity	Protein Binding Metal Ion Binding
	Biological Process	Chromatin Remodeling Inflammatory Response Methylation Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Inflammatory Response Regulation Of Cell Proliferation In Bone Marrow	Chromosome Segregation Protein Maturation
Pathways
Drugs
Diseases
GWAS		Asthma (adult onset) ( 31036433) Metabolite levels ( 23823483) Mitral valve prolapse ( 26301497) Obesity-related traits ( 23251661)
Interacting Genes		3 interacting genes: CHAF1B CIAO2A MORC3	25 interacting genes: AGTRAP APOA2 CIAO1 CMTM6 CREB3L1 DERL1 DGAT2L6 EBAG9 ERGIC3 FKBP7 GJA8 GSC2 KCNIP1 LIME1 MEST PLP2 PLPP6 PLPPR2 PRAF2 RHBDD2 SETD4 SIN3A TMED8 TNFRSF10D VAMP3
Entrez ID		54093	84191
HPRD ID		10743	08010
Ensembl ID		ENSG00000185917	ENSG00000166797
Uniprot IDs		A8MTS1 Q9NVD3	Q9H5X1
PDB IDs			2M5H 3UX2 3UX3
Enriched GO Terms of Interacting Partners?			Endoplasmic Reticulum Membrane Signal Recognition Particle Binding Endoplasmic Reticulum Endoplasmic Reticulum Unfolded Protein Response Phosphatidate Phosphatase Activity
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