CSNK1G1 and PPP1R14A

Number of citations of the paper that reports this interaction (PubMedID 15003508)
0

Data Source:
HPRD (in vitro)

		CSNK1G1	PPP1R14A
Description		casein kinase 1 gamma 1	protein phosphatase 1 regulatory inhibitor subunit 14A
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Plasma Membrane	Cytoplasm Cytosol
	Molecular Function	Nucleotide Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Serine Kinase Activity	Protein Phosphatase Inhibitor Activity Protein Serine/threonine Phosphatase Inhibitor Activity
	Biological Process	Endocytosis Signal Transduction Wnt Signaling Pathway Positive Regulation Of Canonical Wnt Signaling Pathway	Cellular Response To Xenobiotic Stimulus
Pathways			RHO GTPases activate PKNs
Drugs		2-({6-[(3-Chlorophenyl)amino]-9-isopropyl-9H-purin-2-yl}amino)ethanol
Diseases
GWAS		Basophil count ( 32888494) General factor of neuroticism ( 30867560) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monoclonal gammopathy of undetermined significance ( 30737484) Monocyte count ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Myeloid white cell count ( 27863252) Neuroticism ( 29255261) White blood cell count ( 32888494)	Diverticular disease ( 30177863)
Interacting Genes		13 interacting genes: APP CEP76 CLSPN FAM219A FOXO1 IKZF1 KRTAP10-7 MKRN1 PPP1R14A RELA RUNDC3B SNCA WDCP	16 interacting genes: APP CSNK1A1 CSNK1D CSNK1E CSNK1G1 CSNK1G2 CSNK1G3 DAPK1 PRKCA PRKCE PRKCG PRKCH PRKCZ PRKD1 PRNP YWHAZ
Entrez ID		53944	94274
HPRD ID		05886	16291
Ensembl ID		ENSG00000169118	ENSG00000167641
Uniprot IDs		Q8IXA3 Q9HCP0 U3KQB3	Q96A00
PDB IDs		2CMW
Enriched GO Terms of Interacting Partners?		Response To Interleukin-1 Negative Regulation Of MiRNA Transcription Regulation Of Presynapse Organization Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Presynapse Assembly Regulation Of Protein Catabolic Process Amyloid Fibril Formation Positive Regulation Of Small Molecule Metabolic Process Protein-containing Complex Regulation Of Neurotransmitter Uptake Positive Regulation Of Amyloid Precursor Protein Catabolic Process Cellular Response To Copper Ion Microglial Cell Activation Response To Copper Ion Leukocyte Activation Involved In Inflammatory Response Amyloid-beta Complex Regulation Of Amyloid Precursor Protein Catabolic Process Growth Cone Lamellipodium Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Cellular Response To Oxidative Stress Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Protein Complex Oligomerization Regulation Of Neuronal Synaptic Plasticity Positive Regulation Of Interleukin-1 Beta Production Cellular Response To Chemical Stress Macrophage Activation Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Cellular Response To Growth Factor Stimulus Positive Regulation Of Reactive Oxygen Species Metabolic Process Acetylcholine Receptor Activator Activity PTB Domain Binding Positive Regulation Of Interleukin-1 Production Positive Regulation Of Phosphate Metabolic Process Adult Locomotory Behavior Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Negative Regulation Of RNA Biosynthetic Process Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Response To Growth Factor Endosome To Plasma Membrane Transport Vesicle Protein Tetramerization Positive Regulation Of Endothelin Production	Protein Serine Kinase Activity Protein Serine/threonine Kinase Activity Protein Kinase Activity Kinase Activity Protein Phosphorylation Phosphorylation Diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling ATP Binding Regulation Of Cell Communication Regulation Of Signaling Positive Regulation Of Signal Transduction Nucleotide Binding Transferase Activity Regulation Of Signal Transduction Signal Transduction Protein Modification Process Regulation Of Canonical Wnt Signaling Pathway Phosphate-containing Compound Metabolic Process Regulation Of Wnt Signaling Pathway Protein Metabolic Process Positive Regulation Of Canonical Wnt Signaling Pathway Intracellular Signal Transduction Wnt Signaling Pathway Regulation Of Protein Metabolic Process Positive Regulation Of Wnt Signaling Pathway Positive Regulation Of Catabolic Process Regulation Of Protein Localization Cytoplasm Regulation Of Proteolysis Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Localization Endocytosis Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Golgi Organization Response To Norepinephrine Cellular Response To Norepinephrine Stimulus Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity Cytosol Negative Regulation Of Apoptotic Process Plasma Membrane Negative Regulation Of Programmed Cell Death Positive Regulation Of Establishment Of Protein Localization Positive Regulation Of Synaptic Transmission Regulation Of Calcium Ion Transmembrane Transport Negative Regulation Of Protein Metabolic Process Import Into Cell Regulation Of Cellular Component Organization Response To Stress
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