NUDT9 and PBX3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		NUDT9	PBX3
Description		nudix hydrolase 9	PBX homeobox 3
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Mitochondrion Mitochondrial Matrix Cytosol Nuclear Body Cell Junction Nuclear Membrane Extracellular Exosome	Chromatin Nucleus Transcription Regulator Complex
	Molecular Function	Protein Binding Hydrolase Activity ADP-sugar Diphosphatase Activity ADP-ribose Diphosphatase Activity	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Sequence-specific DNA Binding
	Biological Process	ADP Catabolic Process Nucleobase-containing Small Molecule Metabolic Process	Eye Development Regulation Of Respiratory Gaseous Exchange By Nervous System Process Regulation Of DNA-templated Transcription Anterior Compartment Pattern Formation Posterior Compartment Specification Brain Development Respiratory Gaseous Exchange By Respiratory System Adult Locomotory Behavior Animal Organ Morphogenesis Dorsal Spinal Cord Development Positive Regulation Of Transcription By RNA Polymerase II Embryonic Organ Development Neuron Development
Pathways
Drugs		Beta-D-Glucose beta-D-Ribose-5-phosphate
Diseases
GWAS		Blood protein levels ( 30072576) Intelligence (MTAG) ( 29326435)	Dentures ( 31235808) Fish- and plant-related diet ( 32066663) Medication use (opioids) ( 31015401) Number of decayed, missing and filled tooth surfaces or use of dentures ( 31235808) Pulse pressure ( 30578418) Raw vegetable consumption ( 32066663) Refractive error ( 32231278) Response to mTOR inhibitor (everolimus) ( 24009623) Sleep duration ( 30531941) Squamous cell lung carcinoma ( 28604730) Systolic blood pressure ( 30224653 30578418)
Interacting Genes		5 interacting genes: APP EPHA2 GLOD4 PBX3 UBC	66 interacting genes: AGTRAP ARFIP2 ARL6IP1 BIK BSND CAV3 CFTR CIDEB CMTM4 CMTM5 CNTRL COQ8A CPLX2 DESI2 DGAT2L6 FADS6 FAM177A1 FKBP7 FSD2 GAD2 GBP7 HIGD1C HOXA9 HOXB8 HSD17B13 INPP5K INSYN1 ITGB3BP KRT27 KRT31 LIME1 MAGEA1 MAGEC2 MAL2 MBLAC2 MDK MEIS1 MICOS13 MTERF3 NUDT9 PKNOX1 PLIN3 PRB3 PTPN9 RABAC1 REEP5 RHBDD2 RHEX RNF186 RPRM SCAMP1 SFT2D2 SIN3A SMPD2 SYP SYPL1 TFIP11 TMCO2 TMEM196 TPD52L1 TPM3 TRAF1 TRIM44 TVP23B ZNF655 ZNHIT3
Entrez ID		53343	5090
HPRD ID		09353	15938
Ensembl ID		ENSG00000170502	ENSG00000167081
Uniprot IDs		Q8NG26 Q96KB3 Q9BW91	P40426 Q5JS98 Q96AL5
PDB IDs		1Q33 1QVJ
Enriched GO Terms of Interacting Partners?		Molecular Function Activator Activity Amyloid-beta Complex Growth Cone Lamellipodium Adult Locomotory Behavior Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Notochord Cell Development Posterior Compartment Specification Anterior Compartment Pattern Formation Acetylcholine Receptor Activator Activity PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Chemokine Production Endosome To Plasma Membrane Transport Vesicle Adult Behavior Positive Regulation Of Endothelin Production Growth Cone Filopodium Defense Response To Gram-positive Bacterium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Negative Regulation Of Lymphangiogenesis Notochord Formation Axial Mesoderm Formation Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Cell Development Growth Factor Receptor Binding Main Axon Receptor Complex Locomotory Behavior Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Dorsal Spinal Cord Development Compartment Pattern Specification Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Notochord Morphogenesis Pericyte Cell Differentiation Blood Vessel Endothelial Cell Proliferation Involved In Sprouting Angiogenesis	Protein Binding
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