PI4KA and SNX9

Number of citations of the paper that reports this interaction (PubMedID 17242350)
58

Data Source:
BioGRID (pull down)

		PI4KA	SNX9
Description		phosphatidylinositol 4-kinase alpha	sorting nexin 9
Image
GO Annotations	Cellular Component	Cytoplasm Cytosol Plasma Membrane Focal Adhesion Membrane Golgi-associated Vesicle Membrane Extracellular Exosome	Ruffle Cytoplasm Golgi Apparatus Trans-Golgi Network Cytosol Plasma Membrane Clathrin-coated Pit Membrane Clathrin-coated Vesicle Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle Cuticular Plate Cell Projection Extracellular Exosome Presynapse
	Molecular Function	Nucleotide Binding 1-phosphatidylinositol 4-kinase Activity Protein Binding ATP Binding Kinase Activity Transferase Activity Cadherin Binding	Protein Binding 1-phosphatidylinositol Binding Lipid Binding Ubiquitin Protein Ligase Binding Phosphatidylinositol Binding Identical Protein Binding Protein Homodimerization Activity Cadherin Binding Arp2/3 Complex Binding
	Biological Process	Lipid Metabolic Process Phosphatidylinositol Biosynthetic Process Signal Transduction Host-mediated Perturbation Of Viral Process Phosphatidylinositol Phosphate Biosynthetic Process Phosphatidylinositol-mediated Signaling Reorganization Of Cellular Membranes To Establish Viral Sites Of Replication	Mitotic Cell Cycle Mitotic Cytokinesis Intracellular Protein Transport Endocytosis Receptor-mediated Endocytosis Positive Regulation Of Catabolic Process Protein Transport Endosomal Transport Positive Regulation Of Actin Filament Polymerization Cleavage Furrow Formation Positive Regulation Of GTPase Activity Positive Regulation Of Protein Kinase Activity Positive Regulation Of Membrane Protein Ectodomain Proteolysis Cell Division Lipid Tube Assembly Protein-containing Complex Assembly Plasma Membrane Tubulation Regulation Of Synaptic Vesicle Endocytosis
Pathways		Synthesis of PIPs at the ER membrane Synthesis of PIPs at the Golgi membrane	Golgi Associated Vesicle Biogenesis Clathrin-mediated endocytosis
Drugs
Diseases
GWAS		Fulminant type 1 diabetes ( 30552108) Metabolite levels ( 23823483) Monocyte percentage of white cells ( 32888494)	Borderline personality disorder ( 28632202) Heart rate response to beta blockers ( 29478026) L1-L4 bone mineral density x serum urate levels interaction ( 34046847) Lipoprotein (a) - cholesterol levels ( 25575512) Metabolite levels ( 23823483) Platelet distribution width ( 27863252 32888494)
Interacting Genes		10 interacting genes: C8orf33 CD4 CD7 LCK MRPL44 MTNR1B PITPNA SNX9 STRN4 TNNT1	25 interacting genes: ADAM15 ADAM9 AP1G1 CEBPA CLTC DAPK1 DNM1 DNM2 EGFR FASLG ITCH KHDRBS1 LRRK1 MECOM MPHOSPH6 PAK2 PALS2 PI4KA PIK3CA PIK3R5 SOS1 SOS2 TNK2 WAS WASL
Entrez ID		5297	51429
HPRD ID		08972	12072
Ensembl ID		ENSG00000241973	ENSG00000130340
Uniprot IDs		A0A140VK35 B4DYG5 P42356	Q9Y5X1
PDB IDs		6BQ1 9B9G 9BAX	2RAI 2RAJ 2RAK 3DYT 3DYU 3LGE 7OJ9
Enriched GO Terms of Interacting Partners?			SH3 Domain Binding Plasma Membrane Clathrin-coated Pit Vesicle Budding From Membrane Intracellular Signal Transduction Signal Transduction Cell Surface Receptor Signaling Pathway Cytoplasmic Vesicle Regulation Of Plasma Membrane Organization Vesicle Scission Negative Regulation Of Membrane Tubulation Endocytosis Immune System Process Clathrin-coated Vesicle Phosphatidylinositol 3-kinase Complex, Class IB Import Into Cell Intracellular Signaling Cassette Kinase Activity Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Focal Adhesion Regulation Of Hematopoietic Progenitor Cell Differentiation Cytosol Regulation Of Immune System Process Phosphatidylinositol 3-kinase Complex Regulation Of Pro-B Cell Differentiation Regulation Of Cellular Component Organization Extracellular Exosome Phosphatidylinositol 3-kinase Complex, Class IA Cytoplasm Actin Filament-based Movement Epidermal Growth Factor Receptor Signaling Pathway Transferrin Transport Receptor-mediated Endocytosis Positive Regulation Of Protein Metabolic Process Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Lymphoid Progenitor Cell Differentiation Protein Serine Kinase Activity Regulation Of Programmed Cell Death Immune Response-activating Signaling Pathway Receptor Internalization Cellular Response To Type II Interferon Vesicle-mediated Transport Regulation Of ERBB Signaling Pathway Regulation Of Protein Metabolic Process Protein Polymerization Eyelid Development In Camera-type Eye ERBB Signaling Pathway Insulin Receptor Signaling Pathway Apoptotic Process Regulation Of Macromolecule Metabolic Process
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