CD244 and TOMM40L

		CD244	TOMM40L
Description		CD244 molecule	translocase of outer mitochondrial membrane 40 like
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Membrane Membrane Raft	Mitochondrion Mitochondrial Outer Membrane Mitochondrial Outer Membrane Translocase Complex Membrane Protein-containing Complex Pore Complex
	Molecular Function	Protein Binding Signaling Receptor Activity MHC Class I Protein Binding	Molecular_function Protein Transmembrane Transporter Activity Porin Activity
	Biological Process	Adaptive Immune Response Natural Killer Cell Activation Involved In Immune Response Immune System Process Immune Response Signal Transduction Natural Killer Cell Activation Positive Regulation Of Type II Interferon Production Positive Regulation Of Interleukin-8 Production Innate Immune Response Positive Regulation Of Inositol Phosphate Biosynthetic Process Positive Regulation Of Granzyme B Production	Monoatomic Ion Transport Biological_process Protein Transport Protein Import Into Mitochondrial Matrix Transmembrane Transport
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233) Lymphocyte percentage of white cells ( 32888494) Neutrophil percentage of white cells ( 32888494) White blood cell count ( 32888494)
Interacting Genes		11 interacting genes: ACO2 ARHGEF7 CD247 CD48 LAT OLFML2B PCGF1 PDGFRA SH2D1A SH2D1B TOMM40L	3 interacting genes: CD244 FCRLA RAB1B
Entrez ID		51744	84134
HPRD ID		16121	13354
Ensembl ID		ENSG00000122223	ENSG00000158882
Uniprot IDs		Q9BZW8	Q969M1
PDB IDs
Enriched GO Terms of Interacting Partners?		Cell Activation Leukocyte Activation Adaptive Immune Response Lymphocyte Activation Positive Regulation Of Natural Killer Cell Mediated Immunity Positive Regulation Of Immune Response Immune Response Natural Killer Cell Activation Regulation Of Natural Killer Cell Mediated Immunity Platelet-derived Growth Factor Alpha-receptor Activity Negative Regulation Of Microtubule Nucleation Aconitate Hydratase Activity Fc-gamma Receptor III Complex Gamma-delta T Cell Receptor Complex Immune Effector Process Platelet-derived Growth Factor Receptor-alpha Signaling Pathway Phospholipase C Activator Activity Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Metanephric Glomerular Capillary Formation Platelet-derived Growth Factor Receptor-ligand Complex TCR Signalosome	Positive Regulation Of Granzyme B Production Natural Killer Cell Activation Involved In Immune Response Positive Regulation Of Inositol Phosphate Biosynthetic Process External Side Of Plasma Membrane Virion Assembly Establishment Of Endothelial Intestinal Barrier
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