ACSL5 and SELENOI

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ACSL5	SELENOI
Description		acyl-CoA synthetase long chain family member 5	selenoprotein I
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus Mitochondrion Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Golgi Apparatus Membrane
	Molecular Function	Nucleotide Binding Long-chain Fatty Acid-CoA Ligase Activity Protein Binding ATP Binding Ligase Activity Arachidonate-CoA Ligase Activity Oleoyl-CoA Ligase Activity	Ethanolaminephosphotransferase Activity Transferase Activity Phosphotransferase Activity, For Other Substituted Phosphate Groups Metal Ion Binding
	Biological Process	Long-chain Fatty Acid Metabolic Process Lipid Metabolic Process Fatty Acid Metabolic Process Positive Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Long-chain Fatty-acyl-CoA Biosynthetic Process Regulation Of Extrinsic Apoptotic Signaling Pathway	Lipid Metabolic Process Phosphatidylethanolamine Biosynthetic Process Ether Lipid Biosynthetic Process Phospholipid Biosynthetic Process Myelination Glycerophospholipid Biosynthetic Process
Pathways		Synthesis of very long-chain fatty acyl-CoAs	Synthesis of PE
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis ( 32968195) Basophil percentage of white cells ( 32888494) High chromosomal aberration frequency (chromosome type) in genotoxic compound exposure ( 31586183) Mean platelet volume ( 27863252 32888494) Platelet count ( 32888494)
Interacting Genes		13 interacting genes: AQP6 CREB3 EBAG9 FBXO7 PEX12 RETREG3 SELENOI SLC10A1 SLC10A6 SLC16A7 SLC35H1 SLC7A14 TMEM14B	6 interacting genes: ACSL5 APPBP2 CSNK2B EWSR1 MTDH PPAT
Entrez ID		51703	85465
HPRD ID		16139	07616
Ensembl ID		ENSG00000197142	ENSG00000138018
Uniprot IDs		A0A8C8L3F5 Q9ULC5	Q9C0D9
PDB IDs
Enriched GO Terms of Interacting Partners?		Transmembrane Transport Bile Acid:sodium Symporter Activity Organic Anion Transport Carboxylic Acid Transport Organic Acid Transport Symporter Activity Membrane Bile Acid And Bile Salt Transport Monocarboxylic Acid Transport Organic Hydroxy Compound Transport Nitrate Transmembrane Transporter Activity Pyruvate Secondary Active Transmembrane Transporter Activity Positive Regulation Of Deacetylase Activity Glial Cytoplasmic Inclusion Classical Lewy Body Lewy Body Corona Lewy Neurite Sodium-dependent Organic Anion Transmembrane Transporter Activity Sodium-dependent Organic Anion Transport PH-gated Chloride Channel Activity Nitrate Transmembrane Transport Autophagy Secondary Active Monocarboxylate Transmembrane Transporter Activity Peroxisomal Importomer Complex Adaptive Immune Memory Response Involving T Cells And B Cells Lewy Body Core UDP-glucose Transmembrane Transport Ethanolaminephosphotransferase Activity Adaptive Immune Memory Response Pyruvate Transmembrane Transporter Activity Endoplasmic Reticulum-autophagosome Adaptor Activity Negative Regulation Of Intrinsic Apoptotic Signaling Pathway Carbon Dioxide Transmembrane Transporter Activity Carbon Dioxide Transmembrane Transport Peptidase Activator Activity Involved In Apoptotic Process Plasma Membrane Lactate Transport Pyruvate Transmembrane Transport Release From Viral Latency Protein O-linked Glycosylation Via Fucose Protein Import Into Peroxisome Matrix, Substrate Release Lactate Transmembrane Transporter Activity Pyruvate Transport CCR1 Chemokine Receptor Binding Gamma-aminobutyric Acid Import Gamma-aminobutyric Acid Transmembrane Transporter Activity	Positive Regulation Of Activin Receptor Signaling Pathway Protein Kinase CK2 Complex RNA Polymerase II-specific DNA-binding Transcription Factor Binding Negative Regulation Of Viral Life Cycle Fibrillar Center Symbiont-mediated Disruption Of Host Cell PML Body Release From Viral Latency Adiponectin-activated Signaling Pathway Transcription Coregulator Activity Purine-containing Compound Biosynthetic Process Amidophosphoribosyltransferase Activity 'de Novo' AMP Biosynthetic Process 'de Novo' IMP Biosynthetic Process 'de Novo' XMP Biosynthetic Process Positive Regulation Of Long-chain Fatty Acid Import Across Plasma Membrane Positive Regulation Of Long-chain Fatty Acid Import Into Cell Regulation Of Long-chain Fatty Acid Import Into Cell Oleoyl-CoA Ligase Activity Intercellular Canaliculus Nucleolus Nucleoside Phosphate Biosynthetic Process IMP Biosynthetic Process Purine Nucleobase Biosynthetic Process Arachidonate-CoA Ligase Activity Endothelial Tube Morphogenesis AMP Biosynthetic Process GMP Biosynthetic Process
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