UFM1 and SAYSD1

Number of citations of the paper that reports this interaction (PubMedID 36848233)
56

Data Source:
BioGRID (pull down)

		UFM1	SAYSD1
Description		ubiquitin fold modifier 1	SAYSVFN motif domain containing 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Endoplasmic Reticulum	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Cytoplasmic Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding	UFM1-modified Protein Reader Activity
	Biological Process	Brain Development Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Endoplasmic Reticulum Stress Negative Regulation Of Protein Import Into Nucleus Negative Regulation Of Apoptotic Process Reticulophagy Protein Ufmylation Protein K69-linked Ufmylation	Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Rescue Of Stalled Ribosome
Pathways
Drugs
Diseases
GWAS		Aggressiveness in attention deficit hyperactivity disorder ( 27021288) Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Low vWF levels ( 26486471) Schizophrenia ( 30285260 33169155)	Body mass index and diastolic blood pressure (bivariate analysis) ( 33539483) Body mass index and systolic blood pressure (bivariate analysis) ( 33539483) Coronary artery disease ( 32469254) Diastolic blood pressure ( 27841878) Protein C levels ( 28082259)
Interacting Genes		16 interacting genes: ARHGDIA ARHGDIB DIABLO GSK3B INCA1 KCTD21 RPS6KA6 SAYSD1 TSC22D2 UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2E3 UBE2W	5 interacting genes: HSPA8 RPL26 RPL5 RPS2 UFM1
Entrez ID		51569	55776
HPRD ID		15644	12892
Ensembl ID		ENSG00000120686	ENSG00000112167
Uniprot IDs		P61960	Q9NPB0
PDB IDs		1WXS 5HKH 5IA7 5IA8 5IAA 5L95 6H77 7W3N 8BZR 8OHD 8OJ0 8OJ5 8QFC
Enriched GO Terms of Interacting Partners?		Ubiquitin Conjugating Enzyme Activity Protein K48-linked Ubiquitination Ubiquitin-protein Transferase Activity Proteolysis Involved In Protein Catabolic Process Protein Polyubiquitination Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Protein Ubiquitination Protein K11-linked Ubiquitination Protein Modification By Small Protein Conjugation Protein Monoubiquitination Proteolysis Post-translational Protein Modification ATP Binding TOR Signaling Macromolecule Catabolic Process Rho GDP-dissociation Inhibitor Activity Protein Modification Process Transferase Activity Nucleotide Binding TORC1 Signaling Protein Metabolic Process Negative Regulation Of TOR Signaling Catabolic Process Protein K6-linked Ubiquitination Regulation Of TOR Signaling Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Protein Quality Control For Misfolded Or Incompletely Synthesized Proteins Regulation Of Signal Transduction Intracellular Signal Transduction Proteasomal Protein Catabolic Process Regulation Of Microtubule Anchoring At Centrosome Negative Regulation Of Signal Transduction Rho Protein Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Superior Temporal Gyrus Development Negative Regulation Of Type B Pancreatic Cell Development Negative Regulation Of Signaling Negative Regulation Of Mesenchymal Stem Cell Differentiation Negative Regulation Of Glycogen (starch) Synthase Activity Negative Regulation Of Cell Communication Negative Regulation Of TORC1 Signaling Negative Regulation Of BMP Signaling Pathway Negative Regulation Of Embryonic Development Protein Autoubiquitination Protein Catabolic Process Protein K63-linked Ubiquitination Cellular Response To Redox State Negative Regulation Of Mesoderm Development	Ribonucleoprotein Complex Cytosolic Ribosome Cytoplasmic Translation Structural Constituent Of Ribosome Ribosome MRNA 5'-UTR Binding Regulation Of Ubiquitin-protein Transferase Activity Nucleolus Ribosomal Large Subunit Biogenesis Translation Cytosolic Large Ribosomal Subunit Focal Adhesion Protein Metabolic Process Chaperone-mediated Autophagy Translocation Complex Disassembly RNA Binding Regulation Of Translation Involved In Cellular Response To UV Regulation Of Signal Transduction By P53 Class Mediator Lumenal Side Of Lysosomal Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Regulation Of Intracellular Signal Transduction Positive Regulation Of Translation Regulation Of Protein Import Extracellular Exosome Positive Regulation Of Protein Metabolic Process Ribonucleoprotein Complex Biogenesis Protein Targeting To Lysosome Involved In Chaperone-mediated Autophagy RNA Processing C3HC4-type RING Finger Domain Binding Clathrin Coat Disassembly Regulation Of Protein Ubiquitination RRNA Processing Negative Regulation Of Protein Neddylation Protein K69-linked Ufmylation ATP-dependent Protein Disaggregase Activity Vesicle Uncoating Macromolecule Metabolic Process Regulation Of Post-translational Protein Modification RRNA Metabolic Process Chaperone-mediated Autophagy Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Positive Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Ubiquitin Protein Ligase Activity Positive Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Protein Ufmylation Autophagy Ubiquitin Protein Ligase Binding 5S RRNA Binding Cadherin Binding Negative Regulation Of Ubiquitin-protein Transferase Activity Ubiquitin Ligase Inhibitor Activity
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