ACKR4 and CCL25

Number of citations of the paper that reports this interaction (PubMedID 10706668)
0

Data Source:
BioGRID (pull down)
HPRD (in vitro)

		ACKR4	CCL25
Description		atypical chemokine receptor 4	C-C motif chemokine ligand 25
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endosome Early Endosome Plasma Membrane External Side Of Plasma Membrane Membrane Recycling Endosome	Extracellular Region Extracellular Space
	Molecular Function	G Protein-coupled Receptor Activity Chemokine Receptor Activity Scavenger Receptor Activity Protein Binding C-C Chemokine Receptor Activity Chemokine Binding C-C Chemokine Binding	Cytokine Activity Hormone Activity Protein Binding Chemokine Activity CCR10 Chemokine Receptor Binding Chemokine Receptor Binding CCR Chemokine Receptor Binding
	Biological Process	Chemotaxis Immune Response Signal Transduction G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Vesicle-mediated Transport Calcium-mediated Signaling Cell Chemotaxis Chemokine-mediated Signaling Pathway	Positive Regulation Of Cell-matrix Adhesion Immune System Process Chemotaxis Inflammatory Response Immune Response Cell Surface Receptor Signaling Pathway G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Migration Killing Of Cells Of Another Organism Eosinophil Chemotaxis Cell Chemotaxis Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Negative Regulation Of Leukocyte Tethering Or Rolling
Pathways		Chemokine receptors bind chemokines	Chemokine receptors bind chemokines G alpha (i) signalling events
Drugs
Diseases
GWAS		Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Subcortical volume (MOSTest) ( 32665545)	Blood protein levels ( 30072576) Metabolite levels ( 23823483) Neurocognitive impairment in HIV-1 infection (continuous) ( 28447399)
Interacting Genes		11 interacting genes: CCL11 CCL13 CCL19 CCL2 CCL21 CCL25 CCL5 CCL7 CCL8 CDK2 CXCL13	12 interacting genes: ACKR2 ACKR4 CCL17 CCL5 CCR10 CCR9 CXCL11 CXCL12 CXCL17 PF4 PF4V1 SMARCA4
Entrez ID		51554	6370
HPRD ID		07298	03976
Ensembl ID		ENSG00000129048	ENSG00000131142
Uniprot IDs		Q9NPB9	O15444
PDB IDs
Enriched GO Terms of Interacting Partners?		Eosinophil Migration Eosinophil Chemotaxis Chemokine Activity CCR Chemokine Receptor Binding Granulocyte Chemotaxis Chemokine-mediated Signaling Pathway Granulocyte Migration Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Myeloid Leukocyte Migration Leukocyte Chemotaxis Antimicrobial Humoral Response Cell Chemotaxis Cytokine Activity Leukocyte Migration Humoral Immune Response Chemotaxis Locomotion Cytokine-mediated Signaling Pathway Inflammatory Response Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Regulation Of Leukocyte Migration Defense Response To Symbiont Defense Response To Other Organism Killing Of Cells Of Another Organism G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Leukocyte Migration Cell Migration Regulation Of Lymphocyte Chemotaxis Regulation Of Cell Migration Cell Killing Regulation Of Cell Motility Cell Motility Regulation Of Locomotion Positive Regulation Of Leukocyte Chemotaxis Response To Other Organism Chemokine Receptor Binding Mononuclear Cell Migration Immune Response Response To External Biotic Stimulus Defense Response Positive Regulation Of Chemotaxis CCR10 Chemokine Receptor Binding Extracellular Space Positive Regulation Of Lymphocyte Chemotaxis Regulation Of Lymphocyte Migration Intracellular Calcium Ion Homeostasis Regulation Of Chemotaxis Calcium Ion Homeostasis	Cell Chemotaxis Chemotaxis Locomotion Chemokine-mediated Signaling Pathway Cell Migration Chemokine Activity Cell Motility Cytokine-mediated Signaling Pathway Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Immune Response Leukocyte Chemotaxis Immune System Process Antimicrobial Humoral Response Chemokine Receptor Activity C-C Chemokine Binding C-C Chemokine Receptor Activity Cytokine Activity Leukocyte Migration Mononuclear Cell Migration G Protein-coupled Receptor Signaling Pathway Humoral Immune Response CXCR Chemokine Receptor Binding Positive Regulation Of Monocyte Chemotaxis Defense Response Inflammatory Response Extracellular Space Killing Of Cells Of Another Organism Regulation Of Monocyte Chemotaxis Myeloid Leukocyte Migration External Side Of Plasma Membrane Positive Regulation Of Cytosolic Calcium Ion Concentration Calcium-mediated Signaling CXCR3 Chemokine Receptor Binding Defense Response To Symbiont Defense Response To Other Organism Cell Killing Cell Surface Receptor Signaling Pathway Granulocyte Chemotaxis Chemokine Receptor Binding Granulocyte Migration Signal Transduction Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Calcium Ion Transport Response To Other Organism T Cell Chemotaxis Macrophage Chemotaxis Positive Regulation Of Macrophage Chemotaxis G Protein-coupled Receptor Activity Macrophage Migration
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?