CINP and CLUAP1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CINP	CLUAP1
Description		cyclin dependent kinase 2 interacting protein	clusterin associated protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Centrosome Microtubule Organizing Center Cilium Actin Cytoskeleton Intraciliary Transport Particle A Intraciliary Transport Particle B Cell Projection Ciliary Tip Ciliary Base
	Molecular Function	Protein Binding Preribosome Binding	Protein Binding
	Biological Process	DNA Replication DNA Repair DNA Damage Response Ribosome Biogenesis Ribosomal Large Subunit Biogenesis Cell Division	Neural Tube Closure Heart Looping Smoothened Signaling Pathway Floor Plate Formation Cell Projection Organization Axoneme Assembly Intraciliary Anterograde Transport Cilium Assembly Left/right Pattern Formation
Pathways			Intraflagellar transport Intraflagellar transport
Drugs
Diseases
GWAS		Body mass index ( 26426971) Refractive error ( 32231278)	Cerebrospinal fluid α-synuclein levels ( 29959729) FEV1 ( 30804560) Lung function (FVC) ( 30804560) Type 2 diabetes ( 30297969)
Interacting Genes		43 interacting genes: AIRIM AMOTL2 APP ATRIP BAALC BLZF1 BTBD2 CCDC112 CCDC33 CDK2 CFAP161 CLUAP1 COG3 DRC4 FAM161B FBF1 FNDC11 GOLGA2 HNRNPD INCA1 KANK2 MAGEA3 MEOX2 MINAR1 MMADHC MZT1 NDUFB7 PATJ PAX6 POU6F2 PRC1 PRRX1 PSMA1 REL SERTAD1 SNRPD2 SP2 SYCE1 TEPSIN TXNRD3 ZBTB42 ZNF19 ZNF620	7 interacting genes: APP CINP CLU MAGEA11 MYOG UBXN10 VCP
Entrez ID		51550	23059
HPRD ID		16715	10013
Ensembl ID		ENSG00000100865	ENSG00000103351
Uniprot IDs		Q9BW66	J3KNW5 Q96AJ1
PDB IDs		8CIH 8RHN
Enriched GO Terms of Interacting Partners?		Protein Binding	Positive Regulation Of Amyloid Fibril Formation Response To Misfolded Protein Regulation Of Amyloid Fibril Formation Regulation Of Amyloid-beta Clearance Positive Regulation Of Proteolysis Low-density Lipoprotein Particle Receptor Binding Positive Regulation Of Protein Catabolic Process Microglial Cell Activation Positive Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of ATP Metabolic Process Leukocyte Activation Involved In Inflammatory Response Positive Regulation Of Nitric Oxide Metabolic Process Regulation Of Amyloid Precursor Protein Catabolic Process Positive Regulation Of Receptor-mediated Endocytosis Amyloid-beta Complex Regulation Of ATP Metabolic Process Growth Cone Lamellipodium Regulation Of Nitric Oxide Biosynthetic Process Regulation Of Response To Calcium Ion Platelet Alpha Granule Lumen Macrophage Activation Amylin Binding Regulation Of Proteolysis Positive Regulation Of Toll Signaling Pathway Regulation Of Protein Catabolic Process Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Regulation Of Nitric Oxide Metabolic Process Perinuclear Endoplasmic Reticulum Lumen Regulation Of Neuronal Signal Transduction Flavin Adenine Dinucleotide Catabolic Process Regulation Of Purine Nucleotide Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Positive Regulation Of Catabolic Process Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Tumor Necrosis Factor Production Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Regulation Of Receptor-mediated Endocytosis Regulation Of Response To Endoplasmic Reticulum Stress Receptor Ligand Activity Lipoprotein Particle Myeloid Leukocyte Activation Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
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