ATP5PB and MOV10

		ATP5PB	MOV10
Description		ATP synthase peripheral stalk-membrane subunit b	Mov10 RNA helicase
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Mitochondrion Mitochondrial Inner Membrane Mitochondrial Matrix Membrane Proton-transporting ATP Synthase Complex	P-body Extracellular Space Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Cytoplasmic Ribonucleoprotein Granule P Granule
	Molecular Function	Protein Binding Proton Transmembrane Transporter Activity Proton-transporting ATP Synthase Activity, Rotational Mechanism	Nucleotide Binding RNA Binding RNA Helicase Activity Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity 5'-3' RNA Helicase Activity
	Biological Process	Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Substantia Nigra Development Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Transposable Element Silencing Regulatory NcRNA-mediated Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Post-transcriptional Gene Silencing MiRNA-mediated Gene Silencing By MRNA Destabilization Defense Response To Virus Positive Regulation Of MRNA Catabolic Process 3'-UTR-mediated MRNA Destabilization Transposable Element Silencing By MRNA Destabilization Regulation Of Neuron Projection Arborization
Pathways		Formation of ATP by chemiosmotic coupling Cristae formation	Pre-NOTCH Transcription and Translation Oxidative Stress Induced Senescence Oncogene Induced Senescence Ca2+ pathway TP53 Regulates Metabolic Genes MAPK6/MAPK4 signaling Transcriptional Regulation by VENTX Regulation of RUNX1 Expression and Activity RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function Regulation of PTEN mRNA translation Competing endogenous RNAs (ceRNAs) regulate PTEN translation Transcriptional Regulation by MECP2 Transcriptional Regulation by MECP2 Estrogen-dependent gene expression Regulation of MECP2 expression and activity NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux Nuclear events stimulated by ALK signaling in cancer Regulation of CDH11 mRNA translation by microRNAs Regulation of CDH11 mRNA translation by microRNAs Regulation of CDH1 mRNA translation by microRNAs Regulation of NPAS4 mRNA translation Regulation of MITF-M-dependent genes involved in apoptosis TGFBR3 expression Regulation of PD-L1(CD274) translation
Drugs
Diseases
GWAS			Blood pressure ( 21909110) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Body size at age 10 ( 32376654) Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area ( 32963231) Cortical surface area (min-P) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Cortical surface area (visual PC2) ( 32198502) Cortical thickness (min-P) ( 32665545) Cortical thickness (MOSTest) ( 32665545) Diastolic blood pressure ( 27841878 30487518 28739976 27618452 25249183 21909115) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Glaucoma (primary open-angle) ( 33627673) Height ( 31562340) Hip circumference adjusted for BMI ( 25673412) Hypertension ( 21909115 30487518 25249183) Mean arterial pressure ( 30487518) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Medication use (diuretics) ( 31015401) Platelet count ( 32888494) Plateletcrit ( 32888494) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Systolic blood pressure ( 28739976 27841878 27618452 25249183 21909115 30487518) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962)
Interacting Genes		4 interacting genes: CLIC1 MOV10 SPP1 TRIM14	5 interacting genes: ADORA3 ATP5PB RNF10 TSPAN2 YTHDF1
Entrez ID		515	4343
HPRD ID		04467	14732
Ensembl ID		ENSG00000116459	ENSG00000155363
Uniprot IDs		P24539	Q5JR04 Q9HCE1
PDB IDs		8H9F 8H9G 8H9J 8H9K 8H9M 8H9N 8H9Q 8H9R 8H9S 8H9T 8H9U 8H9V 8KHF 8KI3
Enriched GO Terms of Interacting Partners?		Vesicle 5'-3' RNA Helicase Activity Negative Regulation Of Collateral Sprouting Of Intact Axon In Response To Injury Positive Regulation Of Estradiol Secretion Regulation Of Estradiol Secretion Transposable Element Silencing By MRNA Destabilization Androgen Catabolic Process
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