DCDC2 and ZNF432

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		DCDC2	ZNF432
Description		doublecortin domain containing 2	zinc finger protein 432
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Microtubule Organizing Center Cytoskeleton Microtubule Cilium Axoneme Cell Projection Kinocilium	Nucleus Nucleoplasm Nucleolus
	Molecular Function	Protein Binding Kinesin Binding	DNA Binding Damaged DNA Binding Protein Binding Zinc Ion Binding Protein-macromolecule Adaptor Activity Metal Ion Binding
	Biological Process	Neuron Migration Cellular Defense Response Nervous System Development Sensory Perception Of Sound Cell Projection Organization Regulation Of Wnt Signaling Pathway Intracellular Signal Transduction Positive Regulation Of Smoothened Signaling Pathway Dendrite Morphogenesis Cilium Assembly Regulation Of Cilium Assembly	Regulation Of DNA-templated Transcription DNA Damage Response
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS		Airflow obstruction ( 22837378) Estimated glomerular filtration rate ( 31015462 31152163) General cognitive ability ( 29844566) Information processing speed ( 21130836) Uric acid levels ( 21294900)	Bronchodilator response in asthma (inhaled corticosteroid treatment interaction) ( 24280104) Tourette syndrome ( 30818990)
Interacting Genes		19 interacting genes: APP B3GNT5 CENPO CKS1B COMMD9 DYNC2LI1 FAM118A KRTAP5-9 KRTAP9-3 LMO3 MICALL2 MRFAP1 NIF3L1 NMU POP5 PTPRCAP SLC38A2 TOLLIP ZNF432	2 interacting genes: DCDC2 NUP62
Entrez ID		51473	9668
HPRD ID		09308	11716
Ensembl ID		ENSG00000146038	ENSG00000256087
Uniprot IDs		Q9UHG0	O94892
PDB IDs		2DNF
Enriched GO Terms of Interacting Partners?			PTB Domain Binding Nuclear Pore Central Transport Channel Positive Regulation Of Mitotic Cytokinetic Process Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Centrosome Mitotic Centrosome Separation Kinocilium Positive Regulation Of Mitotic Cytokinesis Positive Regulation Of Centriole Replication Centrosome Separation Regulation Of Mitotic Cytokinesis Organelle Assembly Regulation Of Protein Localization To Centrosome Signaling Receptor Complex Adaptor Activity Flemming Body Positive Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Mitotic Spindle Organization Regulation Of Centrosome Duplication Centrosome Cycle SH2 Domain Binding Negative Regulation Of ERBB Signaling Pathway Centriole Assembly Regulation Of Ras Protein Signal Transduction Positive Regulation Of Cytokinesis Regulation Of Centriole Replication Positive Regulation Of ERBB Signaling Pathway Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Organelle Organization Positive Regulation Of Mitotic Nuclear Division Hsp90 Protein Binding Structural Constituent Of Nuclear Pore Hsp70 Protein Binding Negative Regulation Of Ras Protein Signal Transduction Mitotic Metaphase Chromosome Alignment Dendrite Morphogenesis Positive Regulation Of Smoothened Signaling Pathway Cellular Defense Response Kinesin Binding Negative Regulation Of Small GTPase Mediated Signal Transduction Metaphase Chromosome Alignment Regulation Of Centrosome Cycle Cytoskeleton Cellular Senescence Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Signal Transduction Regulation Of ERBB Signaling Pathway RNA Export From Nucleus Chromosome Localization Regulation Of Cytokinesis Microtubule Organizing Center Organization
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