HPCAL4 and TTC12

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		HPCAL4	TTC12
Description		hippocalcin like 4	tetratricopeptide repeat domain 12
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Cytoplasm Centrosome Cytosol Plasma Membrane Nuclear Membrane
	Molecular Function	Calcium Channel Regulator Activity Calcium Ion Binding Protein Binding Protein Domain Specific Binding Metal Ion Binding	Protein Binding
	Biological Process	Central Nervous System Development Response To Heat Regulation Of Signal Transduction	Sperm Axoneme Assembly Cell Projection Organization Axonemal Dynein Complex Assembly
Pathways
Drugs
Diseases
GWAS		Bone mineral density (Ward's triangle area) ( 27397699)	Adult body size ( 32376654) Alcoholic chronic pancreatitis ( 28754779) Body mass index ( 26426971) Feeling guilty ( 29500382) Feeling miserable ( 29500382) General factor of neuroticism ( 30867560) Metabolite levels ( 23823483) Neurociticism ( 29500382) Rosacea symptom severity ( 29771307) Schizophrenia ( 30285260)
Interacting Genes		17 interacting genes: ANKRD33 AQP4 CDSN CEACAM6 CNTROB DTX2 F3 FAM131C LITAF MSRA SCMH1 SPRED1 TEX13B TRPM5 TSC22D3 TTC12 UBE3A	4 interacting genes: AIRIM CDC42 HPCAL4 MIPOL1
Entrez ID		51440	54970
HPRD ID		17113	15577
Ensembl ID		ENSG00000116983	ENSG00000149292
Uniprot IDs		B4DGW9 Q9UM19	A8K8G6 J3KR69 Q53G14 Q9H892
PDB IDs
Enriched GO Terms of Interacting Partners?			Leading Edge Membrane Thioesterase Binding Positive Regulation Of Pinocytosis Apolipoprotein A-I Receptor Binding Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis G Protein-coupled Receptor Signaling Pathway Involved In Heart Process Endothelin Receptor Signaling Pathway Involved In Heart Process Neuron Fate Determination Cardiac Neural Crest Cell Migration Involved In Outflow Tract Morphogenesis Establishment Of Golgi Localization Neuropilin Signaling Pathway GBD Domain Binding Golgi Transport Complex Storage Vacuole Positive Regulation Of Epithelial Cell Proliferation Involved In Lung Morphogenesis Positive Regulation Of Pseudopodium Assembly Endothelin Receptor Signaling Pathway Golgi Localization Regulation Of Attachment Of Spindle Microtubules To Kinetochore Establishment Of Apical/basal Cell Polarity Dendritic Cell Migration Establishment Of Monopolar Cell Polarity GTP-dependent Protein Binding Heart Contraction Cardiac Conduction System Development Embryonic Heart Tube Development Dendritic Spine Morphogenesis Establishment Of Epithelial Cell Apical/basal Polarity Filopodium Assembly Establishment Or Maintenance Of Monopolar Cell Polarity Cell Migration Involved In Heart Development Polarized Epithelial Cell Differentiation
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