RWDD1 and DRG2

Number of citations of the paper that reports this interaction (PubMedID 33961781)
97

Data Source:
BioGRID (proximity labelling technology, affinity chromatography technology, cross-linking study)
HPRD (two hybrid)

		RWDD1	DRG2
Description		RWD domain containing 1	developmentally regulated GTP binding protein 2
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol	Nucleus Nucleoplasm Cytoplasm Cytosol Membrane
	Molecular Function	Protein Binding	Nucleotide Binding RNA Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Cytoplasmic Translation Androgen Receptor Signaling Pathway Cellular Response To Oxidative Stress Cellular Response To Testosterone Stimulus	Cytoplasmic Translation Signal Transduction
Pathways		Protein hydroxylation	Protein hydroxylation
Drugs
Diseases
GWAS			A body shape index ( 34021172) Hip index ( 34021172) Schizophrenia ( 25056061 28991256) Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		4 interacting genes: DRG1 DRG2 NFIX NUDT18	6 interacting genes: EIF4A3 JMJD7 NAB2 RWDD1 TRIM54 TSSK3
Entrez ID		51389	1819
HPRD ID		15286	04286
Ensembl ID		ENSG00000111832	ENSG00000108591
Uniprot IDs		Q9H446	A8MZF9 P55039
PDB IDs		2EBM
Enriched GO Terms of Interacting Partners?		8-hydroxy-dADP Phosphatase Activity 8-oxo-GDP Phosphatase Activity DGDP Catabolic Process DADP Catabolic Process Cytoplasmic Translation GDP Catabolic Process 8-oxo-dGDP Phosphatase Activity GTPase Activity Translation Macromolecule Biosynthetic Process GTP Binding GDP Metabolic Process Nucleoside Diphosphate Phosphatase Activity Hydrolase Activity Potassium Ion Binding Regulation Of Mitotic Spindle Assembly Deoxyribose Phosphate Catabolic Process Deoxyribonucleotide Catabolic Process Regulation Of Spindle Assembly Positive Regulation Of Microtubule Polymerization	Negative Regulation Of Selenocysteine Incorporation Cellular Response To Selenite Ion Peptidyl-lysine 3-dioxygenase Activity Negative Regulation Of Transcription By RNA Polymerase III Selenocysteine Insertion Sequence Binding Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Regulation Of Translation At Postsynapse
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